ATE102214T1 - Homocyclostatin und cyclostatin enthaltende polypeptide als antihypertensiva. - Google Patents
Homocyclostatin und cyclostatin enthaltende polypeptide als antihypertensiva.Info
- Publication number
- ATE102214T1 ATE102214T1 AT88305847T AT88305847T ATE102214T1 AT E102214 T1 ATE102214 T1 AT E102214T1 AT 88305847 T AT88305847 T AT 88305847T AT 88305847 T AT88305847 T AT 88305847T AT E102214 T1 ATE102214 T1 AT E102214T1
- Authority
- AT
- Austria
- Prior art keywords
- homocyclostatin
- cyclostatin
- antihypertensives
- containing polypeptides
- polypeptides
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 108090000783 Renin Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6899287A | 1987-07-01 | 1987-07-01 | |
| EP88305847A EP0297816B1 (de) | 1987-07-01 | 1988-06-24 | Homocyclostatin und Cyclostatin enthaltende Polypeptide als Antihypertensiva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE102214T1 true ATE102214T1 (de) | 1994-03-15 |
Family
ID=22086011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88305847T ATE102214T1 (de) | 1987-07-01 | 1988-06-24 | Homocyclostatin und cyclostatin enthaltende polypeptide als antihypertensiva. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0297816B1 (de) |
| JP (1) | JPH0631313B2 (de) |
| AT (1) | ATE102214T1 (de) |
| CA (1) | CA1321676C (de) |
| DE (1) | DE3888031T2 (de) |
| DK (1) | DK362288A (de) |
| ES (1) | ES2061652T3 (de) |
| FI (1) | FI883135A7 (de) |
| IE (1) | IE61842B1 (de) |
| PT (1) | PT87868B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3902615A1 (de) * | 1988-08-27 | 1990-03-08 | Bayer Ag | Aminomethyl-peptide, verfahren zur herstellung und ihre verwendung in arzneimitteln |
| KR900012945A (ko) * | 1989-02-16 | 1990-09-03 | 가와무라 요시부미 | 렌닌 억제활성을 갖는 펩타이트, 그 제조방법 및 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0184855A3 (de) * | 1984-12-14 | 1989-05-03 | Abbott Laboratories | Reninhemmende Verbindungen |
| US4729985A (en) * | 1985-08-09 | 1988-03-08 | Pfizer Inc. | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues |
| DE3538749A1 (de) * | 1985-10-31 | 1987-05-07 | Merck Patent Gmbh | Peptide |
| EP0314239A3 (de) * | 1987-10-28 | 1990-12-27 | Merck & Co. Inc. | Tripeptid-Renin-Inhibitoren mit N-terminalen Ureid- oder Sulfamid-Gruppen |
-
1988
- 1988-06-24 DE DE3888031T patent/DE3888031T2/de not_active Expired - Fee Related
- 1988-06-24 AT AT88305847T patent/ATE102214T1/de not_active IP Right Cessation
- 1988-06-24 EP EP88305847A patent/EP0297816B1/de not_active Expired - Lifetime
- 1988-06-24 ES ES88305847T patent/ES2061652T3/es not_active Expired - Lifetime
- 1988-06-29 PT PT87868A patent/PT87868B/pt not_active IP Right Cessation
- 1988-06-29 CA CA000570669A patent/CA1321676C/en not_active Expired - Fee Related
- 1988-06-30 IE IE199188A patent/IE61842B1/en not_active IP Right Cessation
- 1988-06-30 DK DK362288A patent/DK362288A/da not_active Application Discontinuation
- 1988-06-30 FI FI883135A patent/FI883135A7/fi not_active Application Discontinuation
- 1988-07-01 JP JP63164852A patent/JPH0631313B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6426596A (en) | 1989-01-27 |
| PT87868A (pt) | 1989-06-30 |
| EP0297816B1 (de) | 1994-03-02 |
| DK362288D0 (da) | 1988-06-30 |
| DE3888031T2 (de) | 1994-06-09 |
| IE61842B1 (en) | 1994-11-30 |
| PT87868B (pt) | 1995-03-01 |
| EP0297816A2 (de) | 1989-01-04 |
| CA1321676C (en) | 1993-08-24 |
| FI883135A0 (fi) | 1988-06-30 |
| EP0297816A3 (en) | 1990-09-05 |
| ES2061652T3 (es) | 1994-12-16 |
| DK362288A (da) | 1989-02-24 |
| DE3888031D1 (de) | 1994-04-07 |
| JPH0631313B2 (ja) | 1994-04-27 |
| IE881991L (en) | 1989-01-01 |
| FI883135A7 (fi) | 1989-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |