FI883135A - Homocyklostatin och cyklostatin innehaollande polypeptider som antihypertensiva medel. - Google Patents

Homocyklostatin och cyklostatin innehaollande polypeptider som antihypertensiva medel. Download PDF

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Publication number
FI883135A
FI883135A FI883135A FI883135A FI883135A FI 883135 A FI883135 A FI 883135A FI 883135 A FI883135 A FI 883135A FI 883135 A FI883135 A FI 883135A FI 883135 A FI883135 A FI 883135A
Authority
FI
Finland
Prior art keywords
homocyclostatin
cyclostatin
polypeptider
antihypertensiva
medel
Prior art date
Application number
FI883135A
Other languages
English (en)
Other versions
FI883135A0 (fi
Inventor
Dennis Jay Hoover
Robert Louis Rosati
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI883135A0 publication Critical patent/FI883135A0/fi
Publication of FI883135A publication Critical patent/FI883135A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI883135A 1987-07-01 1988-06-30 Homocyklostatin och cyklostatin innehaollande polypeptider som antihypertensiva medel. FI883135A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6899287A 1987-07-01 1987-07-01

Publications (2)

Publication Number Publication Date
FI883135A0 FI883135A0 (fi) 1988-06-30
FI883135A true FI883135A (fi) 1989-01-02

Family

ID=22086011

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883135A FI883135A (fi) 1987-07-01 1988-06-30 Homocyklostatin och cyklostatin innehaollande polypeptider som antihypertensiva medel.

Country Status (10)

Country Link
EP (1) EP0297816B1 (fi)
JP (1) JPH0631313B2 (fi)
AT (1) ATE102214T1 (fi)
CA (1) CA1321676C (fi)
DE (1) DE3888031T2 (fi)
DK (1) DK362288A (fi)
ES (1) ES2061652T3 (fi)
FI (1) FI883135A (fi)
IE (1) IE61842B1 (fi)
PT (1) PT87868B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3902615A1 (de) * 1988-08-27 1990-03-08 Bayer Ag Aminomethyl-peptide, verfahren zur herstellung und ihre verwendung in arzneimitteln
KR900012945A (ko) * 1989-02-16 1990-09-03 가와무라 요시부미 렌닌 억제활성을 갖는 펩타이트, 그 제조방법 및 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184855A3 (en) * 1984-12-14 1989-05-03 Abbott Laboratories Resin inhibiting compounds
US4729985A (en) * 1985-08-09 1988-03-08 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
DE3538749A1 (de) * 1985-10-31 1987-05-07 Merck Patent Gmbh Peptide
EP0314239A3 (en) * 1987-10-28 1990-12-27 Merck & Co. Inc. Tripeptide renin inhibitors with n-terminal ureido or sulfamido groups

Also Published As

Publication number Publication date
DE3888031D1 (de) 1994-04-07
ATE102214T1 (de) 1994-03-15
EP0297816B1 (en) 1994-03-02
DE3888031T2 (de) 1994-06-09
EP0297816A3 (en) 1990-09-05
CA1321676C (en) 1993-08-24
PT87868A (pt) 1989-06-30
DK362288D0 (da) 1988-06-30
ES2061652T3 (es) 1994-12-16
FI883135A0 (fi) 1988-06-30
DK362288A (da) 1989-02-24
JPS6426596A (en) 1989-01-27
JPH0631313B2 (ja) 1994-04-27
IE881991L (en) 1989-01-01
EP0297816A2 (en) 1989-01-04
PT87868B (pt) 1995-03-01
IE61842B1 (en) 1994-11-30

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FD Application lapsed

Owner name: PFIZER INC.