PT88580B - Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 - Google Patents

Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 Download PDF

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Publication number
PT88580B
PT88580B PT88580A PT8858088A PT88580B PT 88580 B PT88580 B PT 88580B PT 88580 A PT88580 A PT 88580A PT 8858088 A PT8858088 A PT 8858088A PT 88580 B PT88580 B PT 88580B
Authority
PT
Portugal
Prior art keywords
hydroxy
isomers
propylphenoxy
process according
prepared
Prior art date
Application number
PT88580A
Other languages
English (en)
Portuguese (pt)
Other versions
PT88580A (pt
Inventor
Richard Mathias Weier
Michael Allan Stealey
James Ronald Deason
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT88580A publication Critical patent/PT88580A/pt
Publication of PT88580B publication Critical patent/PT88580B/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT88580A 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 PT88580B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (2)

Publication Number Publication Date
PT88580A PT88580A (pt) 1988-10-01
PT88580B true PT88580B (pt) 1992-11-30

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88580A PT88580B (pt) 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4

Country Status (14)

Country Link
US (1) US4923891A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0308956B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH01132577A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR890005082A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU610246B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3878806T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK530888A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2045052T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI884377L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3007858T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL87800A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO171412C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ226318A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT88580B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
CA2224563A1 (en) 1995-06-12 1996-12-27 G.D. Searle & Co. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations
ATE296114T1 (de) * 1996-02-13 2005-06-15 Searle & Co Zubereitungen, enthaltend einen cyclooxygenase-2- inhibitor und einen leukotrien-b4-rezeptor- antagonisten
ES2207900T3 (es) * 1999-10-06 2004-06-01 Dainippon Ink And Chemicals, Inc. 4-metilen-1,3-dioxolano con grupos funcionales.
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
RU2472790C2 (ru) 2005-11-22 2013-01-20 Сегетис Инк. Кетали глицериллевулината и их применение
CN101896474B (zh) * 2007-10-09 2016-02-03 希凯迪斯股份有限公司 制备缩酮和乙缩醛的方法
WO2010036884A1 (en) 2008-09-25 2010-04-01 Segetis, Inc. Ketal ester derivatives
WO2010151558A1 (en) 2009-06-22 2010-12-29 Segetis, Inc. Ketal compounds and uses thereof
KR20130070608A (ko) 2010-05-10 2013-06-27 세게티스, 인코포레이티드. 미립자 고체에 대한 분산제 및 슬립제로서의 알킬 케탈 에스터 및 그의 제조방법, 및 용도
US20120035376A1 (en) 2010-08-03 2012-02-09 Segetis, Inc. Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
CN103052691B (zh) 2010-08-12 2014-05-28 赛格提斯有限公司 包含羧基酯缩酮聚结物的胶乳涂层组合物、其制备方法和应用
EP2603836A4 (en) 2010-08-12 2017-08-02 Segetis, Inc. Carboxy ester ketal removal compositions, methods of manufacture, and uses thereof
WO2012033813A2 (en) 2010-09-07 2012-03-15 Segetis, Inc. Compositions for dyeing keratin fibers
CN103097604A (zh) 2010-09-13 2013-05-08 赛格提斯有限公司 织物软化剂组合物及其制造方法
KR20130131323A (ko) 2010-10-18 2013-12-03 세게티스, 인코포레이티드. 카복시 에스터 케탈을 포함하는 수희석성 코팅 조성물, 그리고 그의 제조방법 및 용도
WO2014047428A1 (en) 2012-09-21 2014-03-27 Segetis, Inc. Cleaning, surfactant, and personal care compositions
JP2016506383A (ja) 2012-11-29 2016-03-03 サジティス・インコーポレイテッド カルボキシエステルケタール、その製造方法および使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR4493M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-07-09 1966-10-10
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
FI884377A7 (fi) 1989-03-25
PT88580A (pt) 1988-10-01
EP0308956A2 (en) 1989-03-29
JPH01132577A (ja) 1989-05-25
NO884223L (no) 1989-03-28
NO171412C (no) 1993-03-10
NO884223D0 (no) 1988-09-23
KR890005082A (ko) 1989-05-11
FI884377A0 (fi) 1988-09-23
GR3007858T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-08-31
AU610246B2 (en) 1991-05-16
DK530888A (da) 1989-03-25
US4923891A (en) 1990-05-08
ES2045052T3 (es) 1994-01-16
NZ226318A (en) 1991-08-27
FI884377L (fi) 1989-03-25
AU2274188A (en) 1989-04-06
EP0308956A3 (en) 1990-06-13
NO171412B (no) 1992-11-30
DE3878806T2 (de) 1993-07-01
IL87800A (en) 1992-12-01
EP0308956B1 (en) 1993-03-03
IL87800A0 (en) 1989-03-31
DK530888D0 (da) 1988-09-23
DE3878806D1 (de) 1993-04-08

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FG3A Patent granted, date of granting

Effective date: 19920521

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941130