PT87974B - Processo para a preparacao de 1h-pirazole-1-alcanamidas uteis como agentes anti-arritmicos - Google Patents
Processo para a preparacao de 1h-pirazole-1-alcanamidas uteis como agentes anti-arritmicos Download PDFInfo
- Publication number
- PT87974B PT87974B PT87974A PT8797488A PT87974B PT 87974 B PT87974 B PT 87974B PT 87974 A PT87974 A PT 87974A PT 8797488 A PT8797488 A PT 8797488A PT 87974 B PT87974 B PT 87974B
- Authority
- PT
- Portugal
- Prior art keywords
- pyrazole
- diphenyl
- mole
- formula
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7249087A | 1987-07-13 | 1987-07-13 | |
| US20624688A | 1988-06-13 | 1988-06-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87974A PT87974A (pt) | 1989-06-30 |
| PT87974B true PT87974B (pt) | 1995-03-01 |
Family
ID=26753416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87974A PT87974B (pt) | 1987-07-13 | 1988-07-13 | Processo para a preparacao de 1h-pirazole-1-alcanamidas uteis como agentes anti-arritmicos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0299407B1 (el) |
| JP (1) | JPS6463573A (el) |
| AU (1) | AU599251B2 (el) |
| DE (1) | DE3860878D1 (el) |
| DK (1) | DK388188A (el) |
| ES (1) | ES2039514T3 (el) |
| FI (1) | FI883315A (el) |
| GR (1) | GR3001361T3 (el) |
| IL (1) | IL86926A (el) |
| NO (1) | NO883114L (el) |
| NZ (1) | NZ225272A (el) |
| PH (1) | PH24914A (el) |
| PT (1) | PT87974B (el) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4962120A (en) * | 1989-03-22 | 1990-10-09 | Sterling Drug Inc. | 1H-imidazole-1-acetamides |
| US4888352A (en) * | 1989-03-22 | 1989-12-19 | Sterling Drug Inc. | 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use |
| US4925857A (en) * | 1989-03-22 | 1990-05-15 | Sterling Drug Inc. | Pyridinyl-1H-pyrazole-1-alkanamides as antiarrhythmic agents |
| US4898880A (en) * | 1989-03-22 | 1990-02-06 | Sterling Drug Inc. | N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use |
| US4916150A (en) * | 1989-03-22 | 1990-04-10 | Sterling Drug Inc. | 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use |
| US4994482A (en) * | 1989-07-31 | 1991-02-19 | Bristol-Myers Squibb Company | Arylpyrazol derivatives as anti-platelet agents, compositions and use |
| FR2773153A1 (fr) * | 1997-12-29 | 1999-07-02 | Rhone Poulenc Agrochimie | Nouveaux composes fongicides |
| EP1542680B1 (en) * | 2002-09-09 | 2007-03-07 | Amgen Inc. | 1, 4, 5-substituted 1, 2-dihydro-pyrazol-3-one and 3-alkoxy-1h-pyrazole derivatives as tnf-alpha and interleukin lowering agents for the treatment of inflammations |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4182895A (en) * | 1976-12-20 | 1980-01-08 | Sterling Drug Inc. | 1-Amino-lower-alkyl-3,4-diphenyl-1H-pyrazoles |
| CH633677A5 (en) * | 1977-03-28 | 1982-12-31 | Ciba Geigy Ag | Microbicidal composition, process for the preparation of the active compound and its use for the control of phytopathogenic fungi |
| DE3126083A1 (de) * | 1981-07-02 | 1983-01-20 | Basf Ag, 6700 Ludwigshafen | N-substituierte 2-methylnaphthylamide, verfahren zu ihrer herstellung und diese enthaltende fungizide |
| DE3424586A1 (de) * | 1984-07-04 | 1986-01-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 3-aminocarbonylmethoxy-5-phenyl-pyrazol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1988
- 1988-06-30 IL IL86926A patent/IL86926A/xx unknown
- 1988-07-01 PH PH37144A patent/PH24914A/en unknown
- 1988-07-04 NZ NZ225272A patent/NZ225272A/xx unknown
- 1988-07-11 DE DE8888111051T patent/DE3860878D1/de not_active Expired - Fee Related
- 1988-07-11 EP EP88111051A patent/EP0299407B1/en not_active Expired - Lifetime
- 1988-07-11 ES ES198888111051T patent/ES2039514T3/es not_active Expired - Lifetime
- 1988-07-11 AU AU18930/88A patent/AU599251B2/en not_active Ceased
- 1988-07-12 FI FI883315A patent/FI883315A/fi not_active IP Right Cessation
- 1988-07-12 DK DK388188A patent/DK388188A/da not_active Application Discontinuation
- 1988-07-12 NO NO88883114A patent/NO883114L/no unknown
- 1988-07-13 PT PT87974A patent/PT87974B/pt not_active IP Right Cessation
- 1988-07-13 JP JP63174823A patent/JPS6463573A/ja active Pending
-
1991
- 1991-01-24 GR GR90400363T patent/GR3001361T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH24914A (en) | 1990-12-26 |
| NO883114D0 (no) | 1988-07-12 |
| EP0299407A1 (en) | 1989-01-18 |
| AU1893088A (en) | 1989-01-19 |
| IL86926A0 (en) | 1988-11-30 |
| ES2039514T3 (es) | 1993-10-01 |
| GR3001361T3 (en) | 1992-09-11 |
| NZ225272A (en) | 1991-09-25 |
| FI883315A0 (fi) | 1988-07-12 |
| EP0299407B1 (en) | 1990-10-24 |
| NO883114L (no) | 1989-01-16 |
| JPS6463573A (en) | 1989-03-09 |
| DK388188A (da) | 1989-01-16 |
| DK388188D0 (da) | 1988-07-12 |
| FI883315A (fi) | 1989-01-14 |
| DE3860878D1 (de) | 1990-11-29 |
| AU599251B2 (en) | 1990-07-12 |
| IL86926A (en) | 1992-07-15 |
| PT87974A (pt) | 1989-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940818 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960229 |