PT87616A - Process for the preparation of leukotriene antagonists and of pharmaceutical compounds - Google Patents
Process for the preparation of leukotriene antagonists and of pharmaceutical compoundsInfo
- Publication number
- PT87616A PT87616A PT87616A PT8761688A PT87616A PT 87616 A PT87616 A PT 87616A PT 87616 A PT87616 A PT 87616A PT 8761688 A PT8761688 A PT 8761688A PT 87616 A PT87616 A PT 87616A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- preparation
- leukotriene antagonists
- alkoxy
- pharmaceutical compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6659287A | 1987-06-24 | 1987-06-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT87616A true PT87616A (pt) | 1988-06-01 |
PT87616B PT87616B (pt) | 1992-09-30 |
Family
ID=22070480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT87616A PT87616B (pt) | 1987-06-24 | 1988-05-30 | Processo de preparacao de antagonistas do leucotrieno e de composicoes farmaceuticas |
Country Status (11)
Country | Link |
---|---|
US (1) | US5135938A (pt) |
EP (1) | EP0296731B1 (pt) |
JP (1) | JP2677382B2 (pt) |
AT (1) | ATE79873T1 (pt) |
AU (1) | AU1759488A (pt) |
DE (1) | DE3874021T2 (pt) |
DK (1) | DK327188A (pt) |
ES (1) | ES2051850T3 (pt) |
GR (1) | GR3006224T3 (pt) |
PT (1) | PT87616B (pt) |
ZA (1) | ZA884239B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
EP0532674A4 (en) * | 1990-06-06 | 1993-04-07 | Smithkline Beecham Corporation | Leukotriene antagonists |
JP7463108B2 (ja) * | 2017-06-19 | 2024-04-08 | シーカ・テクノロジー・アーゲー | 潜在性硬化剤及び硬化性ポリウレタン組成物 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3868369A (en) | 1972-11-14 | 1975-02-25 | Smithkline Corp | 3-heterocyclicthiomethylcephalosporins |
US3989694A (en) | 1974-12-27 | 1976-11-02 | Smithkline Corporation | 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins |
US4286089A (en) | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
US4048311A (en) | 1976-01-08 | 1977-09-13 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins |
US4220644A (en) | 1976-05-03 | 1980-09-02 | Smithkline Corporation | 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins |
NZ205559A (en) * | 1982-09-23 | 1987-08-31 | Merck Frosst Canada Inc | Leukotriene antagonists, pharmaceutical compositions, and intermediates |
US4661505A (en) * | 1982-11-03 | 1987-04-28 | Eli Lilly And Company | Leukotriene antagonists |
JPS59161366A (ja) * | 1983-03-04 | 1984-09-12 | Zenichi Yoshida | チアジアゾリノン類 |
CA1242195A (en) * | 1983-07-18 | 1988-09-20 | David K. Herron | Leukotriene antagonists |
US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
GB8320943D0 (en) * | 1983-08-03 | 1983-09-07 | Lilly Industries Ltd | Organic compounds |
GB8432144D0 (en) * | 1984-12-20 | 1985-01-30 | Lilly Industries Ltd | Organic compounds |
GB8502258D0 (en) * | 1985-01-30 | 1985-02-27 | Lilly Industries Ltd | Organic compounds |
ATE72431T1 (de) * | 1985-08-31 | 1992-02-15 | Fisons Plc | 5-gliedrige heterocyclische angiotensinumwandlungsenzym-inhibitoren. |
GB8530222D0 (en) * | 1985-12-07 | 1986-01-15 | Lilly Industries Ltd | Organic compounds |
-
1988
- 1988-05-30 PT PT87616A patent/PT87616B/pt not_active IP Right Cessation
- 1988-06-07 AT AT88305185T patent/ATE79873T1/de not_active IP Right Cessation
- 1988-06-07 DE DE8888305185T patent/DE3874021T2/de not_active Expired - Fee Related
- 1988-06-07 ES ES88305185T patent/ES2051850T3/es not_active Expired - Lifetime
- 1988-06-07 EP EP88305185A patent/EP0296731B1/en not_active Expired - Lifetime
- 1988-06-10 AU AU17594/88A patent/AU1759488A/en not_active Abandoned
- 1988-06-14 ZA ZA884239A patent/ZA884239B/xx unknown
- 1988-06-15 JP JP63147940A patent/JP2677382B2/ja not_active Expired - Lifetime
- 1988-06-15 DK DK327188A patent/DK327188A/da not_active Application Discontinuation
-
1990
- 1990-03-30 US US07/502,007 patent/US5135938A/en not_active Expired - Fee Related
-
1992
- 1992-11-12 GR GR920402560T patent/GR3006224T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE3874021D1 (de) | 1992-10-01 |
EP0296731A1 (en) | 1988-12-28 |
ATE79873T1 (de) | 1992-09-15 |
EP0296731B1 (en) | 1992-08-26 |
JPS6426571A (en) | 1989-01-27 |
AU1759488A (en) | 1989-01-05 |
US5135938A (en) | 1992-08-04 |
PT87616B (pt) | 1992-09-30 |
ZA884239B (en) | 1989-06-28 |
JP2677382B2 (ja) | 1997-11-17 |
GR3006224T3 (pt) | 1993-06-21 |
DK327188D0 (da) | 1988-06-15 |
DK327188A (da) | 1988-12-25 |
ES2051850T3 (es) | 1994-07-01 |
DE3874021T2 (de) | 1993-02-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19920312 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19950930 |