PT87053B - Processo para a preparacao de composicoes contraceptivas contendo meletonina e metodo para efectuar a contracepcao - Google Patents

Processo para a preparacao de composicoes contraceptivas contendo meletonina e metodo para efectuar a contracepcao Download PDF

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Publication number
PT87053B
PT87053B PT87053A PT8705388A PT87053B PT 87053 B PT87053 B PT 87053B PT 87053 A PT87053 A PT 87053A PT 8705388 A PT8705388 A PT 8705388A PT 87053 B PT87053 B PT 87053B
Authority
PT
Portugal
Prior art keywords
melatonin
progestogen
daily
administration
days
Prior art date
Application number
PT87053A
Other languages
English (en)
Portuguese (pt)
Other versions
PT87053A (pt
Inventor
Michael Cohen
Original Assignee
Applied Med Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Med Res filed Critical Applied Med Res
Publication of PT87053A publication Critical patent/PT87053A/pt
Publication of PT87053B publication Critical patent/PT87053B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT87053A 1987-03-23 1988-03-23 Processo para a preparacao de composicoes contraceptivas contendo meletonina e metodo para efectuar a contracepcao PT87053B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/029,229 US4855305A (en) 1987-03-23 1987-03-23 Compositions and methods of effecting contraception utilizing melatonin

Publications (2)

Publication Number Publication Date
PT87053A PT87053A (pt) 1989-03-30
PT87053B true PT87053B (pt) 1993-09-30

Family

ID=21847942

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87053A PT87053B (pt) 1987-03-23 1988-03-23 Processo para a preparacao de composicoes contraceptivas contendo meletonina e metodo para efectuar a contracepcao

Country Status (26)

Country Link
US (1) US4855305A (instruction)
EP (1) EP0354921B1 (instruction)
JP (2) JP2965160B2 (instruction)
KR (1) KR890700349A (instruction)
CN (1) CN1041383C (instruction)
AT (1) ATE143807T1 (instruction)
AU (3) AU628784B2 (instruction)
BG (1) BG51075A1 (instruction)
BR (1) BR8807426A (instruction)
CA (1) CA1322527C (instruction)
DD (1) DD269557A5 (instruction)
DE (1) DE3855606T2 (instruction)
EG (1) EG18583A (instruction)
ES (1) ES2009251A6 (instruction)
FI (1) FI894423L (instruction)
GR (1) GR1002146B (instruction)
HU (1) HU208487B (instruction)
IL (1) IL85814A (instruction)
IN (1) IN166946B (instruction)
NZ (1) NZ223989A (instruction)
OA (1) OA09134A (instruction)
PH (1) PH26709A (instruction)
PT (1) PT87053B (instruction)
RU (1) RU2114621C1 (instruction)
WO (1) WO1988007370A1 (instruction)
ZA (1) ZA882079B (instruction)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
EP0300630A3 (en) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin for regulating animal reproduction
IL87574A0 (en) * 1987-08-28 1989-01-31 Regulin Ltd Composition for regulating animal reproduction containing an indole derivative
IN170311B (instruction) * 1989-01-17 1992-03-14 Cohen Michael
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
GR900100024A (el) * 1989-01-17 1991-06-07 Amr Int Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου.
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
AU644367B2 (en) * 1989-05-17 1993-12-09 Applied Medical Research Ltd Use of melatonin derivatives for effecting contraception
IT1243193B (it) * 1990-08-10 1994-05-24 Medea Res Srl Composizioni farmaceutiche orali a base di melatonina
EP0483077B1 (en) * 1990-09-28 1995-12-06 I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi A method for carrying out the synthesis of a contraceptive and menstrual cycle controlling drug having oncostatic, antikinetosic, preventive and therapeutic properties for treatment of mammary tumours and melanomas.
DE122007000073I1 (de) * 1991-05-09 2008-01-31 Neurim Pharma 1991 Melatonin enthaltene Arzneimittel
WO1993007870A1 (en) * 1991-10-18 1993-04-29 Alza Corporation Device for the transdermal administration of melatonin
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
IL105240A (en) * 1992-04-07 1999-04-11 Neurim Pharma 1991 The use of melatonin in the preparation of a drug for the treatment of benign prostatic hyperplasia
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6028064A (en) * 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6620836B1 (en) * 1997-01-22 2003-09-16 Jay Patrick Antiarrhythmic and tranquilizer composition and treatment
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
CN1281363A (zh) 1997-11-14 2001-01-24 阿克佐诺贝尔公司 孕激素-抗孕激素体系
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US6660726B2 (en) 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
AU2001286995B2 (en) * 2000-08-30 2006-11-30 Besins Healthcare Luxembourg Sarl Method for treating erectile dysfunction and increasing libido in men
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
WO2003077900A1 (en) * 2002-03-14 2003-09-25 Prevention, L.L.C. A unifying mechanism and methods to prevent cancer and neurodegenerative diseases
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
MXPA05010871A (es) * 2003-04-11 2005-11-25 Barr Lab Inc Metodos para administrar estrogenos y progestinas.
MXPA06002657A (es) 2003-09-09 2006-06-05 Fumapharm Ag Uso de derivados de acido fumarico para el tratamiento de insuficiencia cardiaca y asma.
BRPI0511569A (pt) * 2004-05-26 2008-01-02 Wyeth Corp composições e métodos para o tratamento de distúrbio disfórico pré-menstrual
EP3459532A1 (en) 2004-10-08 2019-03-27 Fwp Ip Aps Controlled release pharmaceutical compositions comprising a fumaric acid ester
AU2006299833B2 (en) 2005-10-12 2012-04-12 Besins Healthcare Luxembourg Sarl Improved testosterone gel and method of use
EP2068695A2 (en) * 2006-09-13 2009-06-17 Koninklijke Philips Electronics N.V. Device for automatic adjustment of the dose of melatonin and/or delivery of melatonin
US20110112196A1 (en) 2007-02-08 2011-05-12 Matvey E Lukashev Nrf2 screening assays and related methods and compositions
DE102008036825A1 (de) * 2008-08-05 2010-02-11 Aicuris Gmbh & Co. Kg Schwangerschaftsvermeidung durch Gestagene
FR2937862B1 (fr) * 2008-11-03 2010-11-19 Mohammed Ridha Chakroun Kit contraceptif
CN114392228A (zh) * 2014-03-27 2022-04-26 安达卢西亚健康服务部 呈现长期稳定性的褪黑素注射剂的持久制剂
RU2617518C2 (ru) * 2015-07-01 2017-04-25 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
EP0004770B1 (en) * 1978-04-11 1984-06-13 Efamol Limited Pharmaceutical and dietary composition comprising gamma-linolenic acids
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
US4390531A (en) * 1981-08-10 1983-06-28 Syntex Pharmaceuticals International Ltd. Method of contraception using peak progestogen dosage
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
WO1986005093A2 (en) * 1985-03-04 1986-09-12 Cellena (Cell Engineering) A.G. Melatonin compositions and uses thereof
US4746674A (en) * 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors

Also Published As

Publication number Publication date
ES2009251A6 (es) 1989-09-16
FI894423A7 (fi) 1989-09-19
FI894423A0 (fi) 1989-09-19
EG18583A (en) 1993-06-30
JPH1171276A (ja) 1999-03-16
DD269557A5 (de) 1989-07-05
PT87053A (pt) 1989-03-30
IL85814A0 (en) 1990-02-09
ATE143807T1 (de) 1996-10-15
AU8693891A (en) 1991-12-19
DE3855606D1 (de) 1996-11-14
IN166946B (instruction) 1990-08-11
WO1988007370A1 (en) 1988-10-06
CA1322527C (en) 1993-09-28
EP0354921A1 (en) 1990-02-21
AU676523B2 (en) 1997-03-13
EP0354921B1 (en) 1996-10-09
GR880100177A (el) 1989-01-31
CN88101379A (zh) 1988-10-05
GR1002146B (en) 1996-02-19
OA09134A (en) 1991-10-31
RU2114621C1 (ru) 1998-07-10
EP0354921A4 (en) 1991-08-07
AU628784B2 (en) 1992-09-24
DE3855606T2 (de) 1997-02-13
US4855305A (en) 1989-08-08
HUT52954A (en) 1990-09-28
ZA882079B (en) 1988-09-15
JPH02502724A (ja) 1990-08-30
AU5513494A (en) 1994-04-14
AU1683088A (en) 1988-11-02
CN1041383C (zh) 1998-12-30
IL85814A (en) 1992-05-25
FI894423L (fi) 1989-09-19
NZ223989A (en) 1991-08-27
BG51075A1 (en) 1993-02-15
HU208487B (en) 1993-11-29
JP2965160B2 (ja) 1999-10-18
BR8807426A (pt) 1990-04-10
PH26709A (en) 1992-09-15
KR890700349A (ko) 1989-04-24

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930305

MM3A Annulment or lapse

Effective date: 20050905