PT831877E - Efeitos metabolicos de certos analogos da glutationa - Google Patents

Efeitos metabolicos de certos analogos da glutationa

Info

Publication number
PT831877E
PT831877E PT96918156T PT96918156T PT831877E PT 831877 E PT831877 E PT 831877E PT 96918156 T PT96918156 T PT 96918156T PT 96918156 T PT96918156 T PT 96918156T PT 831877 E PT831877 E PT 831877E
Authority
PT
Portugal
Prior art keywords
glutational
analogs
certain
metabolic effects
esters
Prior art date
Application number
PT96918156T
Other languages
English (en)
Inventor
Matthew Lyttle
Lawrence M Kauvar
Amy S Morgan
Borch Richard F University Ctr
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/482,645 external-priority patent/US5767086A/en
Application filed by Telik Inc filed Critical Telik Inc
Publication of PT831877E publication Critical patent/PT831877E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
PT96918156T 1995-06-07 1996-06-05 Efeitos metabolicos de certos analogos da glutationa PT831877E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/482,645 US5767086A (en) 1992-04-03 1995-06-07 Bone marrow stimulation by certain glutathione analogs
US63651696A 1996-04-19 1996-04-19

Publications (1)

Publication Number Publication Date
PT831877E true PT831877E (pt) 2005-03-31

Family

ID=27047352

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96918156T PT831877E (pt) 1995-06-07 1996-06-05 Efeitos metabolicos de certos analogos da glutationa

Country Status (10)

Country Link
EP (1) EP0831877B1 (pt)
JP (2) JPH11507056A (pt)
AT (1) ATE280582T1 (pt)
AU (1) AU715524B2 (pt)
CA (1) CA2221568C (pt)
DE (1) DE69633722T2 (pt)
DK (1) DK0831877T3 (pt)
ES (1) ES2231814T3 (pt)
PT (1) PT831877E (pt)
WO (1) WO1996040205A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251857B1 (en) 1995-12-14 2001-06-26 Novelos Therapeutics, Inc. Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof
RU2089179C1 (ru) * 1995-12-14 1997-09-10 Закрытое акционерное общество "ВАМ" Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования
EP1072608B1 (en) * 1998-04-16 2005-06-15 Teijin Limited Glutathione derivatives and dosage forms thereof
RU2144374C1 (ru) 1998-11-23 2000-01-20 Закрытое акционерное общество "ВАМ" Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток
US20070142267A1 (en) 1998-11-23 2007-06-21 Novelos Therapeutics, Inc. Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
JP2002535359A (ja) * 1999-01-27 2002-10-22 テリック，インコーポレイテッド グルタチオン類縁体を含有する治療用組成物
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
TW200538149A (en) 2004-05-20 2005-12-01 Telik Inc Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
PT1833978E (pt) * 2005-01-06 2008-12-02 Telik Inc Tioéteres de tripeptídeo e tetrapeptídeo
US20120251496A1 (en) * 2011-03-31 2012-10-04 Telik, Inc. Ezatiostat for treating multiple myeloma
BR112013033072B1 (pt) * 2011-06-21 2021-04-13 Nitto Denko Corporation Uso de um agente
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
US10093931B2 (en) 2014-06-17 2018-10-09 Nitto Denko Corporation Apoptosis inducer
US10264976B2 (en) 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
JP2022512077A (ja) 2018-11-16 2022-02-02 日東電工株式会社 Ｒｎａ干渉送達製剤及び悪性腫瘍のための方法
JPWO2020230701A1 (pt) 2019-05-14 2020-11-19

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE469132B (sv) * 1989-06-16 1993-05-17 Kabigen Ab Polypeptider och farmaceutisk komposition innehaallande denna
AU651097B2 (en) * 1990-03-02 1994-07-14 Autoimmune, Inc. Enhancement of the down-regulation of autoimmune diseases by oral administration of autoantigens
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
JP3253127B2 (ja) * 1991-06-07 2002-02-04 帝國製薬株式会社 生理活性ポリペプチド含有製剤

Also Published As

Publication number Publication date
JP4520443B2 (ja) 2010-08-04
CA2221568C (en) 2010-05-04
EP0831877B1 (en) 2004-10-27
ES2231814T3 (es) 2005-05-16
WO1996040205A1 (en) 1996-12-19
JP2006348048A (ja) 2006-12-28
ATE280582T1 (de) 2004-11-15
DE69633722D1 (de) 2004-12-02
JPH11507056A (ja) 1999-06-22
DE69633722T2 (de) 2005-11-03
AU715524B2 (en) 2000-02-03
AU6048196A (en) 1996-12-30
EP0831877A1 (en) 1998-04-01
DK0831877T3 (da) 2005-02-14
CA2221568A1 (en) 1996-12-19

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