ATE202784T1 - Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE202784T1
ATE202784T1 AT95926996T AT95926996T ATE202784T1 AT E202784 T1 ATE202784 T1 AT E202784T1 AT 95926996 T AT95926996 T AT 95926996T AT 95926996 T AT95926996 T AT 95926996T AT E202784 T1 ATE202784 T1 AT E202784T1
Authority
AT
Austria
Prior art keywords
alkyl
dialkylamino
alkylamino
halogen
ether
Prior art date
Application number
AT95926996T
Other languages
English (en)
Inventor
Pascal Anger
Jean-Claude Barriere
Bertrand Bonnavaud
Patrick Lefevre
Jean-Marc Paris
Denis Thibaut
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE202784(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE202784T1 publication Critical patent/ATE202784T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95926996T 1994-08-02 1995-07-31 Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen ATE202784T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409564A FR2723373B1 (fr) 1994-08-02 1994-08-02 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
PCT/FR1995/001026 WO1996004298A1 (fr) 1994-08-02 1995-07-31 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent

Publications (1)

Publication Number Publication Date
ATE202784T1 true ATE202784T1 (de) 2001-07-15

Family

ID=9465984

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95926996T ATE202784T1 (de) 1994-08-02 1995-07-31 Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (13)

Country Link
US (1) US6384014B1 (de)
EP (1) EP0773956B1 (de)
JP (1) JPH10503511A (de)
AT (1) ATE202784T1 (de)
AU (1) AU3117495A (de)
CA (1) CA2196450A1 (de)
DE (1) DE69521615T2 (de)
DK (1) DK0773956T3 (de)
ES (1) ES2160171T3 (de)
FR (1) FR2723373B1 (de)
GR (1) GR3036173T3 (de)
PT (1) PT773956E (de)
WO (1) WO1996004298A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999033480A1 (en) * 1997-12-24 1999-07-08 Ingram Teresa J Compositions comprising equisetum and symphytum and methods for the treatment of symptoms associated with mycoplasma infection
FR2775288B1 (fr) * 1998-02-26 2000-03-31 Rhone Poulenc Rorer Sa Derives de streptogramines, leur preparation et les compositons qui les contiennent
ATE252598T1 (de) * 1999-07-27 2003-11-15 Aventis Pharma Sa Streptograminderivate, ihre herstellung und sie enthaltende zubereitungen
FR2796950B1 (fr) * 1999-07-27 2001-09-21 Aventis Pharma Sa Derives de streptogramines, leur preparation et les compositions qui les contiennent
BR0309398A (pt) 2002-04-19 2005-02-01 Cellular Genomics Inc Composto ou um seu sal, hidrato, solvato, forma cristalina, diastereÈmero, prodroga farmaceuticamente aceitável, ou misturas deles, composição farmacêutica, e, métodos para tratar uma condição envolvida com a cinase em um mamìfero, para tratar câncer, e para identificar uma cinase
WO2004022562A1 (en) 2002-09-09 2004-03-18 Cellular Genomics, Inc. 6-ARYL-IMIDAZO[1,2-a]PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF
US7189723B2 (en) 2003-02-10 2007-03-13 Cgi Pharmaceuticals, Inc. Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
WO2005005429A1 (en) 2003-06-30 2005-01-20 Cellular Genomics, Inc. Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
WO2007092475A2 (en) 2006-02-06 2007-08-16 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
AU2009215191A1 (en) 2008-02-13 2009-08-20 Gilead Connecticut, Inc. 6-aryl-imidaz0[l, 2-a] pyrazine derivatives, method of making, and method of use thereof
ES2744541T3 (es) 2008-12-08 2020-02-25 Gilead Connecticut Inc Inhibidores de imidazopirazina Syk
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
HUE030427T2 (en) 2008-12-08 2017-05-29 Gilead Connecticut Inc Imidazopyrazine Syk inhibitors
EP2545052B1 (de) 2010-03-11 2014-11-12 Gilead Connecticut, Inc. Imidazopyridine als syk-inhibitoren
MD4659B1 (ro) 2013-07-30 2019-11-30 Gilead Connecticut Inc Polimorf al inhibitorilor SYK
UA115815C2 (uk) 2013-07-30 2017-12-26 Гіліад Коннектікут, Інк. Склад на основі інгібіторів syk
PT3076976T (pt) 2013-12-04 2020-12-07 Kronos Bio Inc Métodos para tratar cancros
TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
AU2015290000B2 (en) 2014-07-14 2018-05-17 Gilead Sciences, Inc. Combinations for treating cancers
KR102399996B1 (ko) 2017-08-25 2022-05-20 길리애드 사이언시즈, 인코포레이티드 Syk 억제제의 다형체
KR20210131372A (ko) 2019-02-22 2021-11-02 크로노스 바이오, 인코포레이티드 Syk 억제제로서의 축합된 피라진의 고체 형태

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549063B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549062B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2619008B1 (fr) 1987-08-03 1990-06-29 Cird Utilisation de synergistines dans des compositions pharmaceutiques ou cosmetiques anti-acneiques
FR2674539B1 (fr) * 1991-03-28 1993-05-21 Rhone Poulenc Rorer Sa Procede de preparation enzymatique de macrolactone.
FR2696189B1 (fr) 1992-09-25 1994-11-10 Rhone Poulenc Rorer Sa Polypeptides impliqués dans la biosynthèse des streptogramines, séquences nucléotidiques codant pour ces polypeptides et leur utilisation.
FR2701709B1 (fr) 1993-02-17 1995-04-07 Rhone Poulenc Rorer Sa Forme purifiée de streptograminés, sa préparation et les compositions pharmaceutiques qui la contiennent.
IL121821A (en) 1993-02-17 2000-02-17 Rhone Poulenc Rorer Sa Process for purifying a group A minority component of streptogramin some such purified components and their uses

Also Published As

Publication number Publication date
DK0773956T3 (da) 2001-09-24
ES2160171T3 (es) 2001-11-01
JPH10503511A (ja) 1998-03-31
FR2723373A1 (fr) 1996-02-09
GR3036173T3 (en) 2001-10-31
FR2723373B1 (fr) 1996-09-13
PT773956E (pt) 2001-11-30
DE69521615D1 (de) 2001-08-09
WO1996004298A1 (fr) 1996-02-15
US6384014B1 (en) 2002-05-07
AU3117495A (en) 1996-03-04
DE69521615T2 (de) 2002-05-08
EP0773956B1 (de) 2001-07-04
CA2196450A1 (fr) 1996-02-15
EP0773956A1 (de) 1997-05-21

Similar Documents

Publication Publication Date Title
ATE202784T1 (de) Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen
ES2074846T3 (es) Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
ES2128519T3 (es) Nuevas pirido-tiadiazinas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2123039T3 (es) Nuevas 3-(hidroxi-bencilidenil)-indolin-2-onas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2081187T3 (es) Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
DE69213546D1 (de) Neue Peptid-Verbindungen und Verfahren zur Herstellung davon
ES2098023T3 (es) Compuestos de estructura guanidinica y composiciones farmaceuticas que los contienen.
ES2091310T3 (es) Nuevos derivados de la n-benzoil-prolina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ES2103440T3 (es) Nuevas amidas y sulfonamidas naftalenicas, procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2111871T3 (es) Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
TW252979B (de)
IL97148A0 (en) Oxetanones,their manufacture and pharmaceutical compositions containing them
ES2091570T3 (es) Nuevos derivados peptidicos antagonistas de la bradiquidina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DE69412980D1 (de) Eburnan-Derivate, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
ZA942964B (en) Pyrrolopyrazine compounds processes for their preparation and the pharmaceutical compositions which contain them
ES2076054T3 (es) Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ATE97130T1 (de) 13-brom und 13, 14-dibrom-ergoline, ihre herstellung und verwendung in arzneimitteln.
FI903701A0 (fi) Reninhaemmande amino-oligohydroxiderivat.
SE9203824D0 (sv) Benzofuranylimidazole derivatives a process for the preparation and therapeutical compositions containing the same
DK398189A (da) 2-amino-4-morpholino-6-propyl-1,3,5-triaziner og farmaceutiske praeparater med indhold af saadanne forbindelser
DK0552631T3 (da) Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
ES2103553T3 (es) Nuevos cicloalquil-(b)-indoles, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
IL105599A0 (en) Enantiomers derived from(s)-2-amino-2(3,4-dichlorobenzyl)-1-propanol and pharmaceutical compositions containing same

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee