ATE202784T1 - Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE202784T1
ATE202784T1 AT95926996T AT95926996T ATE202784T1 AT E202784 T1 ATE202784 T1 AT E202784T1 AT 95926996 T AT95926996 T AT 95926996T AT 95926996 T AT95926996 T AT 95926996T AT E202784 T1 ATE202784 T1 AT E202784T1
Authority
AT
Austria
Prior art keywords
alkyl
dialkylamino
alkylamino
halogen
ether
Prior art date
Application number
AT95926996T
Other languages
English (en)
Inventor
Pascal Anger
Jean-Claude Barriere
Bertrand Bonnavaud
Patrick Lefevre
Jean-Marc Paris
Denis Thibaut
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE202784(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE202784T1 publication Critical patent/ATE202784T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT95926996T 1994-08-02 1995-07-31 Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen ATE202784T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409564A FR2723373B1 (fr) 1994-08-02 1994-08-02 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
PCT/FR1995/001026 WO1996004298A1 (fr) 1994-08-02 1995-07-31 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent

Publications (1)

Publication Number Publication Date
ATE202784T1 true ATE202784T1 (de) 2001-07-15

Family

ID=9465984

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95926996T ATE202784T1 (de) 1994-08-02 1995-07-31 Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (13)

Country Link
US (1) US6384014B1 (de)
EP (1) EP0773956B1 (de)
JP (1) JPH10503511A (de)
AT (1) ATE202784T1 (de)
AU (1) AU3117495A (de)
CA (1) CA2196450A1 (de)
DE (1) DE69521615T2 (de)
DK (1) DK0773956T3 (de)
ES (1) ES2160171T3 (de)
FR (1) FR2723373B1 (de)
GR (1) GR3036173T3 (de)
PT (1) PT773956E (de)
WO (1) WO1996004298A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1624999A (en) * 1997-12-24 1999-07-19 Teresa J. Ingram Compositions comprising equisetum and symphytum and methods for the treatment of symptoms associated with mycoplasma infection
FR2775288B1 (fr) * 1998-02-26 2000-03-31 Rhone Poulenc Rorer Sa Derives de streptogramines, leur preparation et les compositons qui les contiennent
ATE252598T1 (de) * 1999-07-27 2003-11-15 Aventis Pharma Sa Streptograminderivate, ihre herstellung und sie enthaltende zubereitungen
FR2796950B1 (fr) * 1999-07-27 2001-09-21 Aventis Pharma Sa Derives de streptogramines, leur preparation et les compositions qui les contiennent
JP2005530739A (ja) 2002-04-19 2005-10-13 セルラー ジェノミクス，インコーポレーテッド イミダゾ［１，２−ａ］ピラジン−８−イルアミン、生成方法、および使用方法
WO2004022562A1 (en) 2002-09-09 2004-03-18 Cellular Genomics, Inc. 6-ARYL-IMIDAZO[1,2-a]PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF
US7160885B2 (en) 2003-02-10 2007-01-09 Cgi Pharmaceuticals, Inc. Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
WO2005005429A1 (en) 2003-06-30 2005-01-20 Cellular Genomics, Inc. Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
WO2005019220A2 (en) 2003-08-11 2005-03-03 Cellular Genomics Inc. Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
US7776535B2 (en) 2006-02-06 2010-08-17 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
EP2252617A1 (de) 2008-02-13 2010-11-24 CGI Pharmaceuticals, Inc. 6-arylimidazo[1,2-a]pyrazinderivate, herstellungsverfahren und verfahren zu deren anwendung
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
EA021293B1 (ru) 2008-12-08 2015-05-29 Джилид Коннектикут, Инк. ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
SG171991A1 (en) 2008-12-08 2011-07-28 Gilead Connecticut Inc Imidazopyrazine syk inhibitors
PT2545052E (pt) 2010-03-11 2015-02-18 Gilead Connecticut Inc Inibidores da syk à base de imidazopiridinas
ES2822285T3 (es) 2013-07-30 2021-04-30 Kronos Bio Inc Polimorfo de inhibidores de SYK
MD4684B1 (ro) 2013-07-30 2020-03-31 Gilead Connecticut INc. Formulări pe bază de imidazopirazine în calitate de inhibitori SYK
EP3076976B1 (de) 2013-12-04 2020-09-02 Gilead Sciences, Inc. Methode zur behandlung von krebs
TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
AU2015290000B2 (en) 2014-07-14 2018-05-17 Gilead Sciences, Inc. Combinations for treating cancers
US11384082B2 (en) 2017-08-25 2022-07-12 Kronos Bio, Inc. Hydrates of polymorphs of 6-(1H-indazol-6-YL)-N-(4-morpholinophenyl)-2,3-dihydroimidazo[1,2-A]pyrazin-8-amine bisemsylate as Syk inhibitors
US11339168B2 (en) 2019-02-22 2022-05-24 Kronos Bio, Inc. Crystalline forms of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine as Syk inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549063B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549062B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2619008B1 (fr) 1987-08-03 1990-06-29 Cird Utilisation de synergistines dans des compositions pharmaceutiques ou cosmetiques anti-acneiques
FR2674539B1 (fr) * 1991-03-28 1993-05-21 Rhone Poulenc Rorer Sa Procede de preparation enzymatique de macrolactone.
FR2696189B1 (fr) 1992-09-25 1994-11-10 Rhone Poulenc Rorer Sa Polypeptides impliqués dans la biosynthèse des streptogramines, séquences nucléotidiques codant pour ces polypeptides et leur utilisation.
IL121821A (en) 1993-02-17 2000-02-17 Rhone Poulenc Rorer Sa Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2701709B1 (fr) 1993-02-17 1995-04-07 Rhone Poulenc Rorer Sa Forme purifiée de streptograminés, sa préparation et les compositions pharmaceutiques qui la contiennent.

Also Published As

Publication number Publication date
PT773956E (pt) 2001-11-30
JPH10503511A (ja) 1998-03-31
EP0773956B1 (de) 2001-07-04
CA2196450A1 (fr) 1996-02-15
GR3036173T3 (en) 2001-10-31
US6384014B1 (en) 2002-05-07
WO1996004298A1 (fr) 1996-02-15
ES2160171T3 (es) 2001-11-01
FR2723373A1 (fr) 1996-02-09
DE69521615T2 (de) 2002-05-08
DE69521615D1 (de) 2001-08-09
EP0773956A1 (de) 1997-05-21
AU3117495A (en) 1996-03-04
DK0773956T3 (da) 2001-09-24
FR2723373B1 (fr) 1996-09-13

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