GR3036173T3 - Purified form of streptogramines, preparation of same and pharmaceutical compositions containing same - Google Patents

Purified form of streptogramines, preparation of same and pharmaceutical compositions containing same

Info

Publication number
GR3036173T3
GR3036173T3 GR20010400545T GR20010400545T GR3036173T3 GR 3036173 T3 GR3036173 T3 GR 3036173T3 GR 20010400545 T GR20010400545 T GR 20010400545T GR 20010400545 T GR20010400545 T GR 20010400545T GR 3036173 T3 GR3036173 T3 GR 3036173T3
Authority
GR
Greece
Prior art keywords
alkyl
dialkylamino
same
streptogramines
alkylamino
Prior art date
Application number
GR20010400545T
Other languages
English (en)
Inventor
Pascal Anger
Jean-Claude Barriere
Bertrand Bonnavaud
Patrick Lefevre
Jean-Marc Paris
Denis Thibaut
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3036173(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of GR3036173T3 publication Critical patent/GR3036173T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR20010400545T 1994-08-02 2001-07-05 Purified form of streptogramines, preparation of same and pharmaceutical compositions containing same GR3036173T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409564A FR2723373B1 (fr) 1994-08-02 1994-08-02 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
PCT/FR1995/001026 WO1996004298A1 (fr) 1994-08-02 1995-07-31 Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent

Publications (1)

Publication Number Publication Date
GR3036173T3 true GR3036173T3 (en) 2001-10-31

Family

ID=9465984

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400545T GR3036173T3 (en) 1994-08-02 2001-07-05 Purified form of streptogramines, preparation of same and pharmaceutical compositions containing same

Country Status (13)

Country Link
US (1) US6384014B1 (el)
EP (1) EP0773956B1 (el)
JP (1) JPH10503511A (el)
AT (1) ATE202784T1 (el)
AU (1) AU3117495A (el)
CA (1) CA2196450A1 (el)
DE (1) DE69521615T2 (el)
DK (1) DK0773956T3 (el)
ES (1) ES2160171T3 (el)
FR (1) FR2723373B1 (el)
GR (1) GR3036173T3 (el)
PT (1) PT773956E (el)
WO (1) WO1996004298A1 (el)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416792B1 (en) * 1997-12-24 2002-07-09 Teresa J. Ingram Compositions comprising equisetum and symphytum and methods for the treatment of symptoms associated with mycoplasma infection
FR2775288B1 (fr) * 1998-02-26 2000-03-31 Rhone Poulenc Rorer Sa Derives de streptogramines, leur preparation et les compositons qui les contiennent
FR2796950B1 (fr) * 1999-07-27 2001-09-21 Aventis Pharma Sa Derives de streptogramines, leur preparation et les compositions qui les contiennent
WO2001007467A1 (fr) * 1999-07-27 2001-02-01 Aventis Pharma S.A. Derives de streptogramines, leur preparation et les compositions qui les contiennent
CA2482991A1 (en) 2002-04-19 2003-10-30 Cellular Genomics, Inc. Imidazo[1,2-a]pyrazin-8-ylamines method of making and method of use thereof
US7312341B2 (en) 2002-09-09 2007-12-25 Cgi Pharmaceuticals, Inc. 6-aryl-imidazo[1,2-a] pyrazin-8-ylamines, method of making, and method of use thereof
US7160885B2 (en) 2003-02-10 2007-01-09 Cgi Pharmaceuticals, Inc. Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
WO2005005429A1 (en) 2003-06-30 2005-01-20 Cellular Genomics, Inc. Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
US7776535B2 (en) 2006-02-06 2010-08-17 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ,インコーポレーテッド 6−アリール−イミダゾ[1,2−a]ピラジン誘導体、その製造方法、及びその使用方法
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
JP5696052B2 (ja) 2008-12-08 2015-04-08 ギリアード コネチカット, インコーポレイテッド イミダゾピラジンsyk阻害剤
CN104744476B (zh) 2008-12-08 2017-04-12 吉利德康涅狄格公司 咪唑并吡嗪syk抑制剂
PT2545052E (pt) 2010-03-11 2015-02-18 Gilead Connecticut Inc Inibidores da syk à base de imidazopiridinas
AP2016009007A0 (en) 2013-07-30 2016-01-31 Gilead Connecticut Inc Formulation of syk inhibitors
ES2822285T3 (es) 2013-07-30 2021-04-30 Kronos Bio Inc Polimorfo de inhibidores de SYK
ES2835549T3 (es) 2013-12-04 2021-06-22 Kronos Bio Inc Métodos de tratamiento de cánceres
TWI662037B (zh) 2013-12-23 2019-06-11 美商基利科學股份有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
MA40075A (fr) 2014-07-14 2016-01-21 Gilead Sciences Inc Combinaisons pour traiter des cancers
KR102399996B1 (ko) 2017-08-25 2022-05-20 길리애드 사이언시즈, 인코포레이티드 Syk 억제제의 다형체
KR20210131372A (ko) 2019-02-22 2021-11-02 크로노스 바이오, 인코포레이티드 Syk 억제제로서의 축합된 피라진의 고체 형태

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549062B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549063B1 (fr) 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2619008B1 (fr) 1987-08-03 1990-06-29 Cird Utilisation de synergistines dans des compositions pharmaceutiques ou cosmetiques anti-acneiques
FR2674539B1 (fr) * 1991-03-28 1993-05-21 Rhone Poulenc Rorer Sa Procede de preparation enzymatique de macrolactone.
FR2696189B1 (fr) 1992-09-25 1994-11-10 Rhone Poulenc Rorer Sa Polypeptides impliqués dans la biosynthèse des streptogramines, séquences nucléotidiques codant pour ces polypeptides et leur utilisation.
IL121821A (en) 1993-02-17 2000-02-17 Rhone Poulenc Rorer Sa Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2701709B1 (fr) 1993-02-17 1995-04-07 Rhone Poulenc Rorer Sa Forme purifiée de streptograminés, sa préparation et les compositions pharmaceutiques qui la contiennent.

Also Published As

Publication number Publication date
JPH10503511A (ja) 1998-03-31
EP0773956B1 (fr) 2001-07-04
FR2723373B1 (fr) 1996-09-13
DK0773956T3 (da) 2001-09-24
ATE202784T1 (de) 2001-07-15
ES2160171T3 (es) 2001-11-01
DE69521615T2 (de) 2002-05-08
WO1996004298A1 (fr) 1996-02-15
AU3117495A (en) 1996-03-04
US6384014B1 (en) 2002-05-07
FR2723373A1 (fr) 1996-02-09
EP0773956A1 (fr) 1997-05-21
CA2196450A1 (fr) 1996-02-15
PT773956E (pt) 2001-11-30
DE69521615D1 (de) 2001-08-09

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