PT830137E - Conjugados ionicos moleculares de derivados n-acilados de poli(2-amino-2-desoxi-d-glucose) e polipeptidos - Google Patents

Conjugados ionicos moleculares de derivados n-acilados de poli(2-amino-2-desoxi-d-glucose) e polipeptidos

Info

Publication number
PT830137E
PT830137E PT96920510T PT96920510T PT830137E PT 830137 E PT830137 E PT 830137E PT 96920510 T PT96920510 T PT 96920510T PT 96920510 T PT96920510 T PT 96920510T PT 830137 E PT830137 E PT 830137E
Authority
PT
Portugal
Prior art keywords
acillated
deoxy
polypeptides
glucose
poly
Prior art date
Application number
PT96920510T
Other languages
English (en)
Inventor
Shalaby W Shalaby
Steven A Jackson
Francis Ignatious
Jeaques-Pierre Moreau
Original Assignee
Kinerton Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinerton Ltd filed Critical Kinerton Ltd
Publication of PT830137E publication Critical patent/PT830137E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PT96920510T 1995-06-06 1996-05-24 Conjugados ionicos moleculares de derivados n-acilados de poli(2-amino-2-desoxi-d-glucose) e polipeptidos PT830137E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/468,947 US5665702A (en) 1995-06-06 1995-06-06 Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides

Publications (1)

Publication Number Publication Date
PT830137E true PT830137E (pt) 2003-10-31

Family

ID=23861854

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96920510T PT830137E (pt) 1995-06-06 1996-05-24 Conjugados ionicos moleculares de derivados n-acilados de poli(2-amino-2-desoxi-d-glucose) e polipeptidos

Country Status (21)

Country Link
US (2) US5665702A (pt)
EP (1) EP0830137B1 (pt)
JP (1) JPH11508289A (pt)
KR (1) KR19990022399A (pt)
CN (1) CN1192152A (pt)
AT (1) ATE245031T1 (pt)
AU (1) AU717188B2 (pt)
BR (1) BR9609031A (pt)
CA (1) CA2222995C (pt)
CZ (1) CZ391697A3 (pt)
DE (1) DE69629114T2 (pt)
DK (1) DK0830137T3 (pt)
ES (1) ES2201188T3 (pt)
HU (1) HUP9901627A3 (pt)
NZ (1) NZ308909A (pt)
PL (1) PL323735A1 (pt)
PT (1) PT830137E (pt)
RU (1) RU2172323C2 (pt)
SI (1) SI9620090A (pt)
SK (1) SK168397A3 (pt)
WO (1) WO1996039160A1 (pt)

Families Citing this family (34)

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US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6479457B2 (en) * 1995-06-06 2002-11-12 Kinerton Limited Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
US5968895A (en) 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
DE69907870T2 (de) 1998-01-29 2004-03-04 Kinerton Ltd., Blanchardstown Verfahren zur herstellung von absorbierbaren mikropartikeln
AU2329199A (en) * 1998-01-29 1999-08-16 Poly-Med, Inc. Absorbable microparticles
IL143481A0 (en) 1998-12-07 2002-04-21 Sod Conseils Rech Applic Glp-1 analogues
JP4532618B2 (ja) * 1999-02-25 2010-08-25 株式会社グライコメディクス 新規糖鎖プライマー
DK1320387T3 (da) 2000-09-13 2012-07-16 Glaxosmithkline Llc Farmaceutiske sammensætninger til vedvarende afgivelse af peptider
US7122622B2 (en) * 2002-04-16 2006-10-17 Biosynthema Inc. Peptide compounds having improved binding affinity to somatostatin receptors
US7244445B2 (en) 2002-07-29 2007-07-17 Poly Med, Inc Conformable, absorbable, solid composite preforms and their use for bone tissue engineering
JP2006506396A (ja) * 2002-10-31 2006-02-23 ファイザー・プロダクツ・インク 固体医薬の液体複合体
WO2004060403A2 (en) 2003-01-06 2004-07-22 Angiochem Inc. Aprotinin and anglos as carriers across the blood-brain barrier
EP2210900A3 (en) 2003-12-16 2010-08-11 Ipsen Pharma Analogues of GLP-1
KR101232201B1 (ko) 2005-07-08 2013-02-12 입센 파마 에스.에이.에스 멜라노코르틴 수용체 리간드
CA2614687C (en) 2005-07-15 2016-03-22 Angiochem Inc. Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
EP2650006A1 (en) 2007-09-07 2013-10-16 Ipsen Pharma S.A.S. Analogues of exendin-4 and exendin-3
AU2008325194B2 (en) 2007-11-05 2012-04-19 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Use melanocortins to treat insulin sensitivity
EP2260060A4 (en) * 2008-04-01 2013-01-16 Univ Cornell ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM
CA2729857A1 (en) 2008-07-04 2010-01-07 Traslational Cancer Drugs Pharma, S.L. Methods for the treatment and diagnosis of cancer
PL2320923T3 (pl) 2008-08-07 2015-06-30 Ipsen Pharma Sas Skrócone analogi peptydu insulinotropowego zależnego od glukozy
EP2987805A3 (en) 2008-08-07 2016-04-13 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide
MX339137B (es) 2008-08-07 2016-05-13 Ipsen Pharma Sas Analogos de polipeptidos insulinotropicos dependientes de glucosa (gip) modificados en n terminal.
JP2012505637A (ja) 2008-10-15 2012-03-08 アンジオケム，インコーポレーテッド Ｇｌｐ−１アゴニストのコンジュゲート及びその使用
MX2011004019A (es) 2008-10-15 2011-06-24 Angiochem Inc Conjugados de etoposido y doxorubicina para entrega de farmacos.
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
BRPI0922611A2 (pt) 2008-12-17 2018-11-06 Angiochem Inc inibidores de metaloproteína de matriz de membrana tipo 1 e usos dos mesmos
US20110293562A1 (en) 2009-02-12 2011-12-01 Proyecto De Biomedicina Cima, S.L. Use of cardiotrophin-1 for the treatment of metabolic diseases
MX2012000016A (es) 2009-07-02 2012-03-26 Angiochem Inc Conjugados de peptidos multimericos y sus usos.
JP5571186B2 (ja) 2009-07-22 2014-08-13 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ ５９位にアミノ酸置換を有するインスリン様増殖因子−１（ｉｇｆ−１）の類似体
US9415012B2 (en) * 2011-06-14 2016-08-16 Ipsen Pharma S.A.S. Sustained-release composition containing peptides as active ingredient
US9962401B2 (en) * 2011-09-27 2018-05-08 Purdue Research Foundation Chitosan derivatives for inactivation of endotoxins and surface protection of nanoparticles
ES2826827T3 (es) 2015-06-15 2021-05-19 Angiochem Inc Métodos para el tratamiento de carcinomatosis leptomeníngea

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS63258579A (ja) * 1987-04-15 1988-10-26 Fuji Boseki Kk 生理活性物質固定化用担体の製造法
US5271945A (en) * 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
DK0544000T3 (da) * 1990-08-17 1997-11-03 Drug Delivery System Inst Ltd N-acetylcarboxymethylchitosanderivater og fremgangsmåde til fremstilling deraf.
US5298488A (en) * 1990-10-26 1994-03-29 Fuji Photo Film Co., Ltd. CM-chitin derivatives and use thereof
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
US5344644A (en) * 1991-08-01 1994-09-06 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release

Also Published As

Publication number Publication date
KR19990022399A (ko) 1999-03-25
EP0830137B1 (en) 2003-07-16
DK0830137T3 (da) 2003-11-03
US5821221A (en) 1998-10-13
US5665702A (en) 1997-09-09
NZ308909A (en) 1999-06-29
HUP9901627A3 (en) 1999-11-29
EP0830137A1 (en) 1998-03-25
CA2222995A1 (en) 1996-12-12
HUP9901627A1 (hu) 1999-09-28
PL323735A1 (en) 1998-04-14
WO1996039160A1 (en) 1996-12-12
ATE245031T1 (de) 2003-08-15
BR9609031A (pt) 1999-12-14
CA2222995C (en) 2005-05-10
RU2172323C2 (ru) 2001-08-20
ES2201188T3 (es) 2004-03-16
AU5878996A (en) 1996-12-24
DE69629114T2 (de) 2004-04-22
EP0830137A4 (en) 2002-06-26
DE69629114D1 (de) 2003-08-21
SI9620090A (sl) 1998-08-31
CN1192152A (zh) 1998-09-02
JPH11508289A (ja) 1999-07-21
AU717188B2 (en) 2000-03-23
CZ391697A3 (cs) 1998-05-13
SK168397A3 (en) 1998-04-08

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