HUP9901627A3 - Ionic molecular conjugates of n-acylated derivatives of poly(2-amino-2-deoxy-d-glucose) and polypeptides - Google Patents

Ionic molecular conjugates of n-acylated derivatives of poly(2-amino-2-deoxy-d-glucose) and polypeptides

Info

Publication number
HUP9901627A3
HUP9901627A3 HU9901627A HUP9901627A HUP9901627A3 HU P9901627 A3 HUP9901627 A3 HU P9901627A3 HU 9901627 A HU9901627 A HU 9901627A HU P9901627 A HUP9901627 A HU P9901627A HU P9901627 A3 HUP9901627 A3 HU P9901627A3
Authority
HU
Hungary
Prior art keywords
deoxy
polypeptides
glucose
poly
amino
Prior art date
Application number
HU9901627A
Other languages
English (en)
Original Assignee
Biomeasure Inc Milford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomeasure Inc Milford filed Critical Biomeasure Inc Milford
Publication of HUP9901627A1 publication Critical patent/HUP9901627A1/hu
Publication of HUP9901627A3 publication Critical patent/HUP9901627A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyamides (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
HU9901627A 1995-06-06 1996-05-24 Ionic molecular conjugates of n-acylated derivatives of poly(2-amino-2-deoxy-d-glucose) and polypeptides HUP9901627A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/468,947 US5665702A (en) 1995-06-06 1995-06-06 Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides

Publications (2)

Publication Number Publication Date
HUP9901627A1 HUP9901627A1 (hu) 1999-09-28
HUP9901627A3 true HUP9901627A3 (en) 1999-11-29

Family

ID=23861854

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901627A HUP9901627A3 (en) 1995-06-06 1996-05-24 Ionic molecular conjugates of n-acylated derivatives of poly(2-amino-2-deoxy-d-glucose) and polypeptides

Country Status (21)

Country Link
US (2) US5665702A (hu)
EP (1) EP0830137B1 (hu)
JP (1) JPH11508289A (hu)
KR (1) KR19990022399A (hu)
CN (1) CN1192152A (hu)
AT (1) ATE245031T1 (hu)
AU (1) AU717188B2 (hu)
BR (1) BR9609031A (hu)
CA (1) CA2222995C (hu)
CZ (1) CZ391697A3 (hu)
DE (1) DE69629114T2 (hu)
DK (1) DK0830137T3 (hu)
ES (1) ES2201188T3 (hu)
HU (1) HUP9901627A3 (hu)
NZ (1) NZ308909A (hu)
PL (1) PL323735A1 (hu)
PT (1) PT830137E (hu)
RU (1) RU2172323C2 (hu)
SI (1) SI9620090A (hu)
SK (1) SK168397A3 (hu)
WO (1) WO1996039160A1 (hu)

Families Citing this family (34)

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US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6479457B2 (en) * 1995-06-06 2002-11-12 Kinerton Limited Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
WO1999038536A1 (en) * 1998-01-29 1999-08-05 Poly-Med Inc. Absorbable microparticles
ES2194437T3 (es) 1998-01-29 2003-11-16 Kinerton Ltd Procedimiento para producir microparticulas absorbibles.
RU2208015C2 (ru) 1998-12-07 2003-07-10 Сосьете Де Консей Де Решерш Э Д'Аппликасьон Сьентифик Сас Аналоги гпп-1
JP4532618B2 (ja) * 1999-02-25 2010-08-25 株式会社グライコメディクス 新規糖鎖プライマー
AU2001289079A1 (en) 2000-09-13 2002-03-26 Praecis Pharmaceuticals Incorporated Pharmaceutical compositions for sustained drug delivery
US7122622B2 (en) * 2002-04-16 2006-10-17 Biosynthema Inc. Peptide compounds having improved binding affinity to somatostatin receptors
US7244445B2 (en) 2002-07-29 2007-07-17 Poly Med, Inc Conformable, absorbable, solid composite preforms and their use for bone tissue engineering
CA2504345A1 (en) * 2002-10-31 2004-05-13 Pfizer Products Inc. Liquid conjugates of solid pharmaceuticals
US9221867B2 (en) 2003-01-06 2015-12-29 Angiochem Inc. Method for transporting a compound across the blood-brain barrier
EP2210900A3 (en) 2003-12-16 2010-08-11 Ipsen Pharma Analogues of GLP-1
CA3044795A1 (en) 2005-07-08 2007-01-18 Ipsen Pharma S.A.S. Melanocortin receptor ligands
WO2007009229A1 (en) 2005-07-15 2007-01-25 Angiochem Inc. Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
EP2650006A1 (en) 2007-09-07 2013-10-16 Ipsen Pharma S.A.S. Analogues of exendin-4 and exendin-3
US9155777B2 (en) 2007-11-05 2015-10-13 Ipsen Pharma S.A.S. Use of melanocortins to treat insulin sensitivity
US8841440B2 (en) * 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
MX2011000147A (es) 2008-07-04 2011-05-24 Traslational Cancer Drugs Pharma S L Metodos para el tratamiento y diagnostico del cancer.
DK2320923T3 (en) 2008-08-07 2015-03-02 Ipsen Pharma Sas Truncated analogues of glucose-dependent insulinotropic polypeptide
EP2769986A3 (en) 2008-08-07 2014-11-26 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
MX2011001031A (es) 2008-08-07 2011-04-26 Ipsen Pharma Sas Analogos de polipeptidos insulinotropicos dependientes de glucosa.
US8921314B2 (en) 2008-10-15 2014-12-30 Angiochem, Inc. Conjugates of GLP-1 agonists and uses thereof
US8828925B2 (en) 2008-10-15 2014-09-09 Angiochem Inc. Etoposide and doxorubicin conjugates for drug delivery
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
US8853353B2 (en) 2008-12-17 2014-10-07 Angiochem, Inc. Membrane type-1 matrix metalloprotein inhibitors and uses thereof
WO2010092218A2 (es) 2009-02-12 2010-08-19 Proyecto De Biomedicina Cima, S.L. Uso de la cardiotrofina-1 para el tratamiento de enfermedades metabólicas
CN102596993A (zh) 2009-07-02 2012-07-18 安吉奥开米公司 多聚体肽结合物以及其应用
RU2511577C2 (ru) 2009-07-22 2014-04-10 Ипсен Фарма С.А.С. Аналоги инсулиноподобного фактора роста-1 (igf-1), содержащие аминокислотную замену в положении 59
ES2718655T3 (es) 2011-06-14 2019-07-03 Ipsen Pharma Sas Composición de liberación sostenida que contiene péptidos como ingrediente activo
US9962401B2 (en) * 2011-09-27 2018-05-08 Purdue Research Foundation Chitosan derivatives for inactivation of endotoxins and surface protection of nanoparticles
US10980892B2 (en) 2015-06-15 2021-04-20 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS63258579A (ja) * 1987-04-15 1988-10-26 Fuji Boseki Kk 生理活性物質固定化用担体の製造法
US5271945A (en) * 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
ATE152455T1 (de) * 1990-08-17 1997-05-15 Drug Delivery System Inst Ltd N-acetylcarboxymethylchitosanderivat und verfahren zur herstellung
US5298488A (en) * 1990-10-26 1994-03-29 Fuji Photo Film Co., Ltd. CM-chitin derivatives and use thereof
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
US5344644A (en) * 1991-08-01 1994-09-06 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release

Also Published As

Publication number Publication date
SI9620090A (sl) 1998-08-31
HUP9901627A1 (hu) 1999-09-28
SK168397A3 (en) 1998-04-08
US5665702A (en) 1997-09-09
EP0830137A1 (en) 1998-03-25
CN1192152A (zh) 1998-09-02
PT830137E (pt) 2003-10-31
ATE245031T1 (de) 2003-08-15
CZ391697A3 (cs) 1998-05-13
RU2172323C2 (ru) 2001-08-20
AU5878996A (en) 1996-12-24
CA2222995C (en) 2005-05-10
DK0830137T3 (da) 2003-11-03
EP0830137B1 (en) 2003-07-16
BR9609031A (pt) 1999-12-14
JPH11508289A (ja) 1999-07-21
CA2222995A1 (en) 1996-12-12
DE69629114T2 (de) 2004-04-22
ES2201188T3 (es) 2004-03-16
EP0830137A4 (en) 2002-06-26
KR19990022399A (ko) 1999-03-25
DE69629114D1 (de) 2003-08-21
NZ308909A (en) 1999-06-29
US5821221A (en) 1998-10-13
PL323735A1 (en) 1998-04-14
WO1996039160A1 (en) 1996-12-12
AU717188B2 (en) 2000-03-23

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