PT82934B - Processo de preparacao de derivados n-metilados da ergolina - Google Patents

Processo de preparacao de derivados n-metilados da ergolina

Info

Publication number
PT82934B
PT82934B PT82934A PT8293486A PT82934B PT 82934 B PT82934 B PT 82934B PT 82934 A PT82934 A PT 82934A PT 8293486 A PT8293486 A PT 8293486A PT 82934 B PT82934 B PT 82934B
Authority
PT
Portugal
Prior art keywords
denotes
ergoline
hydrogen atom
preparation process
formula
Prior art date
Application number
PT82934A
Other languages
English (en)
Other versions
PT82934A (fr
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of PT82934A publication Critical patent/PT82934A/pt
Publication of PT82934B publication Critical patent/PT82934B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT82934A 1985-07-11 1986-07-07 Processo de preparacao de derivados n-metilados da ergolina PT82934B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8510620A FR2584720B1 (fr) 1985-07-11 1985-07-11 Procede de preparation de derives n-methyles de l'ergoline

Publications (2)

Publication Number Publication Date
PT82934A PT82934A (fr) 1986-08-01
PT82934B true PT82934B (pt) 1989-01-30

Family

ID=9321195

Family Applications (1)

Application Number Title Priority Date Filing Date
PT82934A PT82934B (pt) 1985-07-11 1986-07-07 Processo de preparacao de derivados n-metilados da ergolina

Country Status (11)

Country Link
US (1) US4754037A (pt)
EP (1) EP0208622B1 (pt)
JP (1) JPH0667936B2 (pt)
KR (1) KR930010497B1 (pt)
AT (1) ATE44742T1 (pt)
CA (1) CA1261319A (pt)
DE (1) DE3664471D1 (pt)
ES (1) ES2000330A6 (pt)
FR (1) FR2584720B1 (pt)
GR (1) GR861782B (pt)
PT (1) PT82934B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584719B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation des derives n-methyles du lysergol et du methoxy-10a lumilysergol
US6063908A (en) * 1996-07-02 2000-05-16 Roche Diagnostics Corporation Reagents for lysergic acid diethylamide immunoassay
US6326501B1 (en) * 2000-04-19 2001-12-04 Hoffmann-La Roche Inc. Methylation of indole compounds using dimethyl carbonate
CN113480532B (zh) * 2021-07-06 2022-08-16 福安药业集团重庆博圣制药有限公司 一种尼麦角林合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA631701A (en) * 1961-11-28 Sandoz A.G. Compounds of the lysergic acid series alkylated at the indol nitrogen atom
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
AT251200B (de) * 1962-07-13 1966-12-27 Farmaceutici Italia Verfahren zur Herstellung neuer Derivate von Dihydro-D-lysergsäureamid und 1-Methyl-dihydro-D-lysergsäureamid
US3879554A (en) * 1970-03-20 1975-04-22 Farmaceutici Italia Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders
DE2618033A1 (de) * 1976-04-24 1977-11-10 Basf Ag Verfahren zur herstellung von aralkylarylaminen und alkylarylaminen
YU40004B (en) * 1977-07-21 1985-06-30 Lek Tovarna Farmacevtskih Praocess for preparing n-substituted esters of 9,10-dihydrlysergic acid
IT1094965B (it) * 1978-04-05 1985-08-10 Corvi Mora E Procedimento di preparazione di derivati del lisergolo
IT1114212B (it) * 1979-03-07 1986-01-27 Anic Spa Procedimento per la preparazione di alchil ammine aromatiche
CS231214B1 (en) * 1982-03-12 1984-10-15 Antonin Cerny Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Also Published As

Publication number Publication date
CA1261319A (fr) 1989-09-26
JPH0667936B2 (ja) 1994-08-31
FR2584720B1 (fr) 1987-10-02
ATE44742T1 (de) 1989-08-15
DE3664471D1 (en) 1989-08-24
EP0208622B1 (fr) 1989-07-19
PT82934A (fr) 1986-08-01
US4754037A (en) 1988-06-28
KR870001208A (ko) 1987-03-12
JPS6216482A (ja) 1987-01-24
ES2000330A6 (es) 1988-02-16
GR861782B (en) 1986-11-10
FR2584720A1 (fr) 1987-01-16
EP0208622A1 (fr) 1987-01-14
KR930010497B1 (ko) 1993-10-25

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