DE69105618D1 - Derivate des 1,2,5,6-Tetrahydropyridin-3-caboxaldehydoxims, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel. - Google Patents

Derivate des 1,2,5,6-Tetrahydropyridin-3-caboxaldehydoxims, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.

Info

Publication number
DE69105618D1
DE69105618D1 DE69105618T DE69105618T DE69105618D1 DE 69105618 D1 DE69105618 D1 DE 69105618D1 DE 69105618 T DE69105618 T DE 69105618T DE 69105618 T DE69105618 T DE 69105618T DE 69105618 D1 DE69105618 D1 DE 69105618D1
Authority
DE
Germany
Prior art keywords
caboxaldehyde
tetrahydropyridine
oxime
medicaments
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69105618T
Other languages
English (en)
Other versions
DE69105618T2 (de
Inventor
Emilio Toja
Carla Bonetti
Fernando Barzaghi
Giulio Galliani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of DE69105618D1 publication Critical patent/DE69105618D1/de
Application granted granted Critical
Publication of DE69105618T2 publication Critical patent/DE69105618T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE69105618T 1990-05-15 1991-05-15 Derivate des 1,2,5,6-Tetrahydropyridin-3-caboxaldehydoxims, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel. Expired - Fee Related DE69105618T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20311A IT1241138B (it) 1990-05-15 1990-05-15 Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali

Publications (2)

Publication Number Publication Date
DE69105618D1 true DE69105618D1 (de) 1995-01-19
DE69105618T2 DE69105618T2 (de) 1995-05-04

Family

ID=11165637

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69105618T Expired - Fee Related DE69105618T2 (de) 1990-05-15 1991-05-15 Derivate des 1,2,5,6-Tetrahydropyridin-3-caboxaldehydoxims, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.

Country Status (9)

Country Link
US (1) US5204479A (de)
EP (1) EP0457680B1 (de)
JP (1) JP2901783B2 (de)
AT (1) ATE115132T1 (de)
CA (1) CA2042558A1 (de)
DE (1) DE69105618T2 (de)
DK (1) DK0457680T3 (de)
ES (1) ES2064937T3 (de)
IT (1) IT1241138B (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
CA725633A (en) * 1966-01-11 Dr. F. Raschig, G.M.B.H., Chemical Works Ethers of pyridine-aldoxime n-oxides
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4408054A (en) * 1981-11-12 1983-10-04 Hoechst-Roussel Pharmaceuticals Inc. Oximes of 4-benzoyl-piperidines
US4533675A (en) * 1984-04-17 1985-08-06 The United States Of America As Represented By The Department Of Health And Human Services Carbamates of colchicine for treatment of gout
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1222529B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali

Also Published As

Publication number Publication date
IT9020311A1 (it) 1991-11-15
CA2042558A1 (fr) 1991-11-16
EP0457680A1 (de) 1991-11-21
EP0457680B1 (de) 1994-12-07
IT1241138B (it) 1993-12-29
ES2064937T3 (es) 1995-02-01
JPH04226958A (ja) 1992-08-17
ATE115132T1 (de) 1994-12-15
JP2901783B2 (ja) 1999-06-07
DK0457680T3 (da) 1995-05-08
IT9020311A0 (it) 1990-05-15
DE69105618T2 (de) 1995-05-04
US5204479A (en) 1993-04-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HOECHST MARION ROUSSEL, PUTEAUX, FR

8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY CEDEX, FR

8339 Ceased/non-payment of the annual fee