PT81382B - Processo para a preparacao de espiro-heteroazolonas - Google Patents
Processo para a preparacao de espiro-heteroazolonasInfo
- Publication number
- PT81382B PT81382B PT81382A PT8138285A PT81382B PT 81382 B PT81382 B PT 81382B PT 81382 A PT81382 A PT 81382A PT 8138285 A PT8138285 A PT 8138285A PT 81382 B PT81382 B PT 81382B
- Authority
- PT
- Portugal
- Prior art keywords
- nitrogen
- hydrogen
- methine
- alkyl
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1984/001767 WO1986002647A1 (en) | 1984-10-30 | 1984-10-30 | Spiro-heteroazolones for treatment of diabetes complications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT81382A PT81382A (en) | 1985-11-01 |
| PT81382B true PT81382B (pt) | 1987-11-30 |
Family
ID=22182314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT81382A PT81382B (pt) | 1984-10-30 | 1985-10-28 | Processo para a preparacao de espiro-heteroazolonas |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0180421B1 (pt) |
| JP (1) | JPS61109789A (pt) |
| KR (1) | KR870000625B1 (pt) |
| AT (1) | ATE66228T1 (pt) |
| AU (1) | AU553839B2 (pt) |
| DE (1) | DE3583791D1 (pt) |
| DK (1) | DK166150C (pt) |
| ES (1) | ES8704168A1 (pt) |
| FI (1) | FI83322C (pt) |
| GR (1) | GR852606B (pt) |
| HU (1) | HU198051B (pt) |
| IE (1) | IE58287B1 (pt) |
| IL (1) | IL76855A0 (pt) |
| PH (1) | PH23491A (pt) |
| PL (2) | PL152316B1 (pt) |
| PT (1) | PT81382B (pt) |
| WO (1) | WO1986002647A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537892A (en) * | 1983-09-14 | 1985-08-27 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
| US4952694A (en) * | 1988-07-27 | 1990-08-28 | Pfizer Inc. | Novel resolution process for racemic spiro-hydantoins |
| US5006657A (en) * | 1988-07-27 | 1991-04-09 | Pfizer Inc. | Intermediates in a resolution process for racemic spiro hydantoins |
| US5037831A (en) * | 1990-05-21 | 1991-08-06 | American Home Products Corporation | Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2449030A1 (de) * | 1974-10-11 | 1976-05-20 | Schering Ag | Neue pyridin-derivate |
| CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
| US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4283409A (en) * | 1979-10-29 | 1981-08-11 | Pfizer Inc. | Imidazolone derivatives |
-
1984
- 1984-10-30 HU HU844630A patent/HU198051B/hu not_active IP Right Cessation
- 1984-10-30 WO PCT/US1984/001767 patent/WO1986002647A1/en active IP Right Grant
-
1985
- 1985-10-25 EP EP85307712A patent/EP0180421B1/en not_active Expired - Lifetime
- 1985-10-25 AT AT85307712T patent/ATE66228T1/de not_active IP Right Cessation
- 1985-10-25 DE DE8585307712T patent/DE3583791D1/de not_active Expired - Fee Related
- 1985-10-28 IL IL76855A patent/IL76855A0/xx not_active IP Right Cessation
- 1985-10-28 PH PH32977A patent/PH23491A/en unknown
- 1985-10-28 ES ES548271A patent/ES8704168A1/es not_active Expired
- 1985-10-28 PT PT81382A patent/PT81382B/pt not_active IP Right Cessation
- 1985-10-28 PL PL1985255978A patent/PL152316B1/pl unknown
- 1985-10-28 JP JP60239657A patent/JPS61109789A/ja active Pending
- 1985-10-28 PL PL1985281584A patent/PL152323B1/pl unknown
- 1985-10-29 KR KR1019850007992A patent/KR870000625B1/ko not_active IP Right Cessation
- 1985-10-29 DK DK495285A patent/DK166150C/da not_active IP Right Cessation
- 1985-10-29 AU AU49164/85A patent/AU553839B2/en not_active Ceased
- 1985-10-29 GR GR852606A patent/GR852606B/el unknown
- 1985-11-01 IE IE269585A patent/IE58287B1/en not_active IP Right Cessation
-
1986
- 1986-06-19 FI FI862634A patent/FI83322C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL255978A1 (en) | 1987-07-13 |
| FI83322C (fi) | 1991-06-25 |
| HUT40659A (en) | 1987-01-28 |
| PT81382A (en) | 1985-11-01 |
| DK495285D0 (da) | 1985-10-29 |
| PL152323B1 (en) | 1990-12-31 |
| FI862634A0 (fi) | 1986-06-19 |
| FI862634A (fi) | 1986-06-19 |
| PH23491A (en) | 1989-08-16 |
| EP0180421B1 (en) | 1991-08-14 |
| FI83322B (fi) | 1991-03-15 |
| GR852606B (pt) | 1986-03-04 |
| AU4916485A (en) | 1986-05-08 |
| JPS61109789A (ja) | 1986-05-28 |
| DK166150C (da) | 1993-08-09 |
| PL152316B1 (en) | 1990-12-31 |
| IE58287B1 (en) | 1993-08-25 |
| KR860003262A (ko) | 1986-05-21 |
| ES548271A0 (es) | 1987-03-16 |
| ES8704168A1 (es) | 1987-03-16 |
| KR870000625B1 (ko) | 1987-03-26 |
| DE3583791D1 (de) | 1991-09-19 |
| DK166150B (da) | 1993-03-15 |
| IE852695L (en) | 1986-04-30 |
| HU198051B (en) | 1989-07-28 |
| EP0180421A1 (en) | 1986-05-07 |
| WO1986002647A1 (en) | 1986-05-09 |
| IL76855A0 (en) | 1986-02-28 |
| DK495285A (da) | 1986-05-01 |
| AU553839B2 (en) | 1986-07-31 |
| ATE66228T1 (de) | 1991-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19951130 |