DK495285D0 - Spiro-heteroazolon-forbindelser og farmaceutiske praeparater - Google Patents

Spiro-heteroazolon-forbindelser og farmaceutiske praeparater

Info

Publication number
DK495285D0
DK495285D0 DK495285A DK495285A DK495285D0 DK 495285 D0 DK495285 D0 DK 495285D0 DK 495285 A DK495285 A DK 495285A DK 495285 A DK495285 A DK 495285A DK 495285 D0 DK495285 D0 DK 495285D0
Authority
DK
Denmark
Prior art keywords
nitrogen
hydrogen
methine
alkyl
carbon atoms
Prior art date
Application number
DK495285A
Other languages
English (en)
Other versions
DK166150B (da
DK166150C (da
DK495285A (da
Inventor
Christopher A Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK495285D0 publication Critical patent/DK495285D0/da
Publication of DK495285A publication Critical patent/DK495285A/da
Publication of DK166150B publication Critical patent/DK166150B/da
Application granted granted Critical
Publication of DK166150C publication Critical patent/DK166150C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
DK495285A 1984-10-30 1985-10-29 Spirooeimidazolidin-4,5'(6'h)-quinolinaa-2,5-dion-forbindelser og farmaceutiske praeparater indeholdende disse DK166150C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1984/001767 WO1986002647A1 (en) 1984-10-30 1984-10-30 Spiro-heteroazolones for treatment of diabetes complications
US8401767 1984-10-30

Publications (4)

Publication Number Publication Date
DK495285D0 true DK495285D0 (da) 1985-10-29
DK495285A DK495285A (da) 1986-05-01
DK166150B DK166150B (da) 1993-03-15
DK166150C DK166150C (da) 1993-08-09

Family

ID=22182314

Family Applications (1)

Application Number Title Priority Date Filing Date
DK495285A DK166150C (da) 1984-10-30 1985-10-29 Spirooeimidazolidin-4,5'(6'h)-quinolinaa-2,5-dion-forbindelser og farmaceutiske praeparater indeholdende disse

Country Status (17)

Country Link
EP (1) EP0180421B1 (da)
JP (1) JPS61109789A (da)
KR (1) KR870000625B1 (da)
AT (1) ATE66228T1 (da)
AU (1) AU553839B2 (da)
DE (1) DE3583791D1 (da)
DK (1) DK166150C (da)
ES (1) ES8704168A1 (da)
FI (1) FI83322C (da)
GR (1) GR852606B (da)
HU (1) HU198051B (da)
IE (1) IE58287B1 (da)
IL (1) IL76855A0 (da)
PH (1) PH23491A (da)
PL (2) PL152323B1 (da)
PT (1) PT81382B (da)
WO (1) WO1986002647A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537892A (en) * 1983-09-14 1985-08-27 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
US4952694A (en) * 1988-07-27 1990-08-28 Pfizer Inc. Novel resolution process for racemic spiro-hydantoins
US5006657A (en) * 1988-07-27 1991-04-09 Pfizer Inc. Intermediates in a resolution process for racemic spiro hydantoins
US5037831A (en) * 1990-05-21 1991-08-06 American Home Products Corporation Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2449030A1 (de) * 1974-10-11 1976-05-20 Schering Ag Neue pyridin-derivate
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4147795A (en) * 1977-02-11 1979-04-03 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4283409A (en) * 1979-10-29 1981-08-11 Pfizer Inc. Imidazolone derivatives

Also Published As

Publication number Publication date
KR860003262A (ko) 1986-05-21
AU553839B2 (en) 1986-07-31
HU198051B (en) 1989-07-28
PL152323B1 (en) 1990-12-31
FI862634A (fi) 1986-06-19
PL255978A1 (en) 1987-07-13
DE3583791D1 (de) 1991-09-19
JPS61109789A (ja) 1986-05-28
EP0180421B1 (en) 1991-08-14
PL152316B1 (en) 1990-12-31
IL76855A0 (en) 1986-02-28
DK166150B (da) 1993-03-15
DK166150C (da) 1993-08-09
IE58287B1 (en) 1993-08-25
PH23491A (en) 1989-08-16
FI862634A0 (fi) 1986-06-19
IE852695L (en) 1986-04-30
ES548271A0 (es) 1987-03-16
ES8704168A1 (es) 1987-03-16
HUT40659A (en) 1987-01-28
PT81382B (pt) 1987-11-30
PT81382A (en) 1985-11-01
ATE66228T1 (de) 1991-08-15
GR852606B (da) 1986-03-04
WO1986002647A1 (en) 1986-05-09
KR870000625B1 (ko) 1987-03-26
EP0180421A1 (en) 1986-05-07
FI83322B (fi) 1991-03-15
DK495285A (da) 1986-05-01
AU4916485A (en) 1986-05-08
FI83322C (fi) 1991-06-25

Similar Documents

Publication Publication Date Title
PH25859A (en) Composition for treatment of ischemic disorder
AU2246292A (en) Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
BR9503536A (pt) Composto processo para sua preparação seu uso e composição farmacêutica
ZA894508B (en) Pharmaceutical compounds
HUT49847A (en) Fungicides comprising n-(phenylalkyl)-benzamide derivatives as active ingredient
DK495285A (da) Spiro-heteroazolon-forbindelser og farmaceutiske praeparater
AU2983792A (en) Diaminomethyleneamino substituted substituted phenyl thiazoles
ES8606295A1 (es) Un procedimiento para la preparacion de nuevas espiro-3-heteroazolidindionas.
AU5494290A (en) Antirhinoviral pyridazinamines
EG16563A (en) Aldose reductase inhibiting 5-(2-alkoxyphenyl)thiazolidinediones
ES2073871T3 (es) Tiazolidin-2,4-dionas en el tratamiento de la hipertension.
ATE109003T1 (de) Therapeutisches mittel gegen pollakiurie, harndrang oder harninkontinenz, das alpha-phenyl- alpha-pyridylalkan-carbonsäurederivate enthält.
GR3015002T3 (en) 1,4-Dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents.
DE69528984D1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
ES8505667A1 (es) Procedimiento para preparar 4-(sustituida alquil)-n-(1,3-ditiolan-2-ilideno)anilina
DE69011174D1 (de) Catecholaminester.

Legal Events

Date Code Title Description
PBP Patent lapsed