PT78986B - Coumarin derivatives pharmaceutical compositions containing the same and use thereof in the treatment of cancer - Google Patents

Coumarin derivatives pharmaceutical compositions containing the same and use thereof in the treatment of cancer

Info

Publication number
PT78986B
PT78986B PT78986A PT7898684A PT78986B PT 78986 B PT78986 B PT 78986B PT 78986 A PT78986 A PT 78986A PT 7898684 A PT7898684 A PT 7898684A PT 78986 B PT78986 B PT 78986B
Authority
PT
Portugal
Prior art keywords
cancer
treatment
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT78986A
Other languages
English (en)
Portuguese (pt)
Other versions
PT78986A (pt
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of PT78986A publication Critical patent/PT78986A/pt
Publication of PT78986B publication Critical patent/PT78986B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT78986A 1983-07-29 1984-07-27 Coumarin derivatives pharmaceutical compositions containing the same and use thereof in the treatment of cancer PT78986B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8348791A IT1212882B (it) 1983-07-29 1983-07-29 Derivati basici della cumarina

Publications (2)

Publication Number Publication Date
PT78986A PT78986A (pt) 1985-02-20
PT78986B true PT78986B (en) 1986-06-18

Family

ID=11268572

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78986A PT78986B (en) 1983-07-29 1984-07-27 Coumarin derivatives pharmaceutical compositions containing the same and use thereof in the treatment of cancer

Country Status (25)

Country Link
US (1) US4737517A (hu)
EP (1) EP0133766B1 (hu)
JP (1) JPS6054378A (hu)
KR (1) KR870001483B1 (hu)
AR (2) AR240816A1 (hu)
AT (1) ATE60329T1 (hu)
AU (1) AU581853B2 (hu)
BE (1) BE900225A (hu)
CH (1) CH662563A5 (hu)
DE (1) DE3483989D1 (hu)
DK (1) DK354784A (hu)
ES (4) ES534581A0 (hu)
FI (1) FI85269C (hu)
FR (1) FR2549832B1 (hu)
GR (1) GR82014B (hu)
HU (2) HUT36815A (hu)
IL (1) IL72515A (hu)
IN (1) IN161176B (hu)
IT (1) IT1212882B (hu)
LU (1) LU85476A1 (hu)
MX (1) MX162759A (hu)
NO (1) NO843042L (hu)
NZ (1) NZ209003A (hu)
PT (1) PT78986B (hu)
ZA (1) ZA845670B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5516629A (en) 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US5484951A (en) * 1990-10-19 1996-01-16 Octamer, Incorporated 5-iodo-6-amino-6-nitroso-1,2-benzopyrones useful as cytostatic and antiviral agents
US5482975A (en) * 1991-10-22 1996-01-09 Octamer, Inc. Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents
US5877185A (en) * 1991-10-22 1999-03-02 Octamer, Inc. Synergistic compositions useful as anti-tumor agents
US5783599A (en) * 1993-02-24 1998-07-21 Octamer Inc Methods of treating cancer and viral infections with 5-iodo-6-amino-and 5-iodo-6-nitroso-1 2-benzopyrones
AU673916B2 (en) * 1993-04-13 1996-11-28 Morinaga Milk Industry Company Limited Coumarin derivative and use thereof
DE10352535A1 (de) * 2003-11-07 2005-06-16 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Partikel enthaltenden Flüssigkeit
US20050245489A1 (en) * 2004-05-03 2005-11-03 Pinney Kevin G Chromene-containing compounds with anti-tubulin and vascular targeting activity
US7456214B2 (en) * 2004-05-03 2008-11-25 Baylor University Chromene-containing compounds with anti-tubulin and vascular targeting activity
BRPI0404130A (pt) * 2004-09-20 2006-05-02 Univ Rio De Janeiro cumarinas substituìdas, processo de produção de tais cumarinas e composições contendo as mesmas
CN104529972B (zh) * 2014-10-10 2016-05-18 北京工业大学 蛋白激酶抑制剂香豆素及其制备方法和医药应用
KR102053748B1 (ko) 2017-12-20 2019-12-09 강원대학교산학협력단 쿠마린 유도체를 포함하는 알레르기성 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3515721A (en) * 1967-06-26 1970-06-02 Cassella Farbwerke Mainkur Ag 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners
BE761985A (fr) * 1970-10-19 1971-07-01 Recordati Chem Pharm Procede de preparation de n-alcoyl-dimethylamines
US3880885A (en) * 1971-11-23 1975-04-29 Sandoz Ag Tertiary aminoethyl isochromans and isocoumarins
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
IT1160366B (it) * 1978-12-19 1987-03-11 F I D I A Spa Applicazioni in campo farmacologico e terapeutico dell'8-cloro-3(beta-dietilamincetil)-4-metil-7-etossi-carbonilmetossi cumarina cloridrato preparato allo stato puro con procedimento selettivo con particolare riguardo alla sua attivita' anti-aggregante piastrinica
US4321270A (en) * 1981-01-29 1982-03-23 E. R. Squibb & Sons, Inc. Substituted chromans
CA1205028A (en) * 1981-07-01 1986-05-27 Jerald C. Hinshaw Fluorescent chelates and labeled specific binding reagents prepared therefrom

Also Published As

Publication number Publication date
US4737517A (en) 1988-04-12
CH662563A5 (fr) 1987-10-15
NZ209003A (en) 1988-04-29
PT78986A (pt) 1985-02-20
ES8602739A1 (es) 1985-12-16
ES8700246A1 (es) 1986-11-16
BE900225A (fr) 1985-01-28
AR240816A2 (es) 1991-02-28
HU199819B (en) 1990-03-28
FI842997A (fi) 1985-01-31
FR2549832B1 (fr) 1987-08-14
EP0133766B1 (en) 1991-01-23
ES8706139A1 (es) 1987-06-01
IL72515A (en) 1992-05-25
AR240816A1 (es) 1991-02-28
FR2549832A1 (fr) 1985-02-01
ATE60329T1 (de) 1991-02-15
NO843042L (no) 1985-01-30
KR850001189A (ko) 1985-03-16
IL72515A0 (en) 1984-11-30
IN161176B (hu) 1987-10-10
FI842997A0 (fi) 1984-07-27
JPH0475911B2 (hu) 1992-12-02
DK354784D0 (da) 1984-07-19
AR240926A1 (es) 1991-03-27
FI85269C (fi) 1992-03-25
ES545238A0 (es) 1986-11-16
ES545239A0 (es) 1986-07-16
AR240926A2 (es) 1991-03-27
ES534581A0 (es) 1985-12-16
JPS6054378A (ja) 1985-03-28
ES8608503A1 (es) 1986-07-16
FI85269B (fi) 1991-12-13
GR82014B (hu) 1984-12-12
MX162759A (es) 1991-06-25
AU581853B2 (en) 1989-03-09
IT1212882B (it) 1989-11-30
EP0133766A3 (en) 1985-12-27
EP0133766A2 (en) 1985-03-06
AU3127484A (en) 1985-01-31
HUT36815A (en) 1985-10-28
IT8348791A0 (it) 1983-07-29
ES545240A0 (es) 1987-06-01
DE3483989D1 (de) 1991-02-28
DK354784A (da) 1985-01-30
KR870001483B1 (ko) 1987-08-13
ZA845670B (en) 1985-03-27
LU85476A1 (fr) 1984-12-06

Similar Documents

Publication Publication Date Title
IL72028A0 (en) Aminomethyl-oxooxazolidinylbenzene derivatives and pharmaceutical compositions containing them
DE3372705D1 (en) Pharmaceutical composition and its use
NZ220345A (en) Imidazoquinolinylether derivatives and pharmaceutical compositions containing them
NZ220880A (en) Di-tert-butyl-phenol derivatives and pharmaceutical compositions
NZ208959A (en) Insulin derivatives and pharmaceutical compositions
IL72566A (en) Androst-5-en-17-one and 5alpha-androstan-17-one derivatives and pharmaceutical compositions containing the same
EP0138421A3 (en) Hydroxypyridinone derivatives and pharmaceutical compositions containing them
NZ221996A (en) Imidazo-pyridine derivatives and pharmaceutical compositions
NZ220171A (en) Dihydro-benzopyran derivatives and pharmaceutical compositions
EP0172721A3 (en) Use of phlorizin or its derivatives in the treatment of cancer
PT78986B (en) Coumarin derivatives pharmaceutical compositions containing the same and use thereof in the treatment of cancer
NZ209064A (en) N 6 -diarylalkyl-adenosine derivatives and pharmaceutical compositions
NZ210105A (en) Oxazolidine derivatives and pharmaceutical compositions
PH20168A (en) 7-carboxymethoxyphenylacetamino-3-cephem derivatives and their pharmaceutical compositions
IL72562A0 (en) Quinazoline derivatives and pharmaceutical compositions containing them
GB2057872B (en) Use of glycerylphosphoryl derivatives in the therapy of dislipaemia hepatitis and like pathological conditions and pharmaceutical compositions therefor
DE3473444D1 (en) Acylindole derivatives and pharmaceutical compositions containing them
NZ208694A (en) Rooperol derivatives and pharmaceutical compositions
IL91451A0 (en) Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
PH19575A (en) Cephalosporing derivatives and pharmaceutical compositions thereof
IL73224A (en) 2-dioxacycloalkylthiopenem derivatives and pharmaceutical compositions containing them
NZ223051A (en) Carbamoyloxylabdane derivatives and pharmaceutical compositions
NZ205732A (en) Thiatriazine derivatives and pharmaceutical compositions
GB2201171B (en) Compositions for use in the treatment of cellulosic materials and their preparation
NZ203649A (en) 2-beta-d-ribofuranosylselenazole-4-carboxamide derivatives and pharmaceutical compositions

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19921219