PT725795E - Formas de cadeia simples do quarteto de hormonas glicoproteicas - Google Patents

Formas de cadeia simples do quarteto de hormonas glicoproteicas

Info

Publication number
PT725795E
PT725795E PT95928220T PT95928220T PT725795E PT 725795 E PT725795 E PT 725795E PT 95928220 T PT95928220 T PT 95928220T PT 95928220 T PT95928220 T PT 95928220T PT 725795 E PT725795 E PT 725795E
Authority
PT
Portugal
Prior art keywords
hormones
quartet
forms
glycoprotetic
glycoprotein hormone
Prior art date
Application number
PT95928220T
Other languages
English (en)
Inventor
Irving Boime
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of PT725795E publication Critical patent/PT725795E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT95928220T 1994-08-12 1995-08-01 Formas de cadeia simples do quarteto de hormonas glicoproteicas PT725795E (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28939694A 1994-08-12 1994-08-12
US31059094A 1994-09-22 1994-09-22
US33462994A 1994-11-04 1994-11-04
US35159194A 1994-12-07 1994-12-07

Publications (1)

Publication Number Publication Date
PT725795E true PT725795E (pt) 2004-05-31

Family

ID=27501506

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95928220T PT725795E (pt) 1994-08-12 1995-08-01 Formas de cadeia simples do quarteto de hormonas glicoproteicas

Country Status (14)

Country Link
EP (1) EP0725795B1 (pt)
KR (1) KR960704932A (pt)
CN (1) CN1157408C (pt)
AT (1) ATE257843T1 (pt)
AU (1) AU703718B2 (pt)
CA (1) CA2173750C (pt)
DE (1) DE69532436T2 (pt)
DK (1) DK0725795T3 (pt)
ES (1) ES2210307T3 (pt)
FI (1) FI120150B (pt)
HU (1) HU227311B1 (pt)
NO (1) NO317394B1 (pt)
PT (1) PT725795E (pt)
WO (1) WO1996005224A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2183564C (en) * 1994-02-18 2010-07-13 William R. Moyle Methods for altering fertility
WO1998021238A1 (fr) * 1996-11-12 1998-05-22 Teikoku Hormone Mfg. Co., Ltd. Gonadotrophine chorionique equine, monocatenaire et recombinee
US5883073A (en) * 1997-04-03 1999-03-16 Washington University Single-chain double-alpha peptide
US6693074B1 (en) * 1997-09-19 2004-02-17 Washington University Cystine depleted glycoprotein hormones
KR100642599B1 (ko) * 1997-09-22 2006-11-10 유니버시티 어브 메릴랜드, 발티모어 갑상선 자극 호르몬의 변이체 및 이에 근거한 방법
US6103501A (en) * 1997-11-17 2000-08-15 Washington University Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof
US6635256B1 (en) * 1998-10-19 2003-10-21 Washington University Glycoprotein hormone compositions comprising two β subunits and methods of use thereof
CA2344277A1 (en) * 1998-09-22 2000-03-30 University Of Maryland, Baltimore Cystine knot growth factor mutants
JP2001333772A (ja) 2000-04-25 2001-12-04 Washington Univ 可変性の活性を有する単鎖稔性ホルモン
IL154297A0 (en) * 2000-08-11 2003-09-17 Applied Res Glycoproteins, their preparation and use
WO2002036626A1 (en) * 2000-11-02 2002-05-10 Maxygen Aps Single-chain multimeric polypeptides
US6987172B2 (en) 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
JP4809352B2 (ja) * 2004-09-02 2011-11-09 イーライ リリー アンド カンパニー 線維芽細胞成長因子２１の突然変異タンパク質
WO2013010840A2 (en) 2011-07-18 2013-01-24 Arts Biologics A/S Long acting biologically active luteinizing hormone (lh) compound
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CN103539860B (zh) * 2013-11-01 2014-12-03 广州优联康医药科技有限公司 一种长效重组人促卵泡激素融合蛋白
CN103539861B (zh) * 2013-11-01 2015-02-18 广州联康生物科技有限公司 长效重组人促卵泡激素融合蛋白
CN103554269B (zh) * 2013-11-01 2015-02-11 广州联康生物科技有限公司 重组猪促卵泡激素融合蛋白
CN103539862B (zh) 2013-11-01 2015-04-01 广州联康生物科技有限公司 一种长效重组促卵泡激素及其应用
BR102016006222A2 (pt) * 2016-03-22 2017-09-26 Universidade De São Paulo - Usp Process of production and purification of recombinant hydrogen hydrogen hybrid or non-hybrid, recombinant hydrogen hydrogen hybrids or non-hybrid, vectors of expression, and uses of recombinant glicoprotetic hormones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0578328B1 (en) * 1983-11-02 1999-12-29 Applied Research Systems ARS Holding N.V. Material and methods for the production of a heterodimeric human LH with a Met42 Val55 alpha subunit
JP3045539B2 (ja) * 1989-02-21 2000-05-29 ワシントン ユニバーシティ 改変型生殖ホルモン
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
CA2082424C (en) * 1990-05-08 2003-09-23 Robert K. Campbell Analogs of glycoprotein hormones having altered immunological characteristics, efficacy and/or receptor specificity

Also Published As

Publication number Publication date
EP0725795A4 (en) 1998-05-06
CN1131952A (zh) 1996-09-25
EP0725795A1 (en) 1996-08-14
DE69532436T2 (de) 2004-11-25
ES2210307T3 (es) 2004-07-01
HU227311B1 (en) 2011-03-28
AU3206695A (en) 1996-03-07
EP0725795B1 (en) 2004-01-14
KR960704932A (ko) 1996-10-09
NO961433L (no) 1996-06-11
HUT75900A (en) 1997-05-28
NO317394B1 (no) 2004-10-25
CA2173750C (en) 2011-03-22
WO1996005224A1 (en) 1996-02-22
ATE257843T1 (de) 2004-01-15
NO961433D0 (no) 1996-04-11
AU703718B2 (en) 1999-04-01
FI961600A (fi) 1996-04-11
DE69532436D1 (de) 2004-02-19
CA2173750A1 (en) 1996-02-22
DK0725795T3 (da) 2004-05-17
FI120150B (fi) 2009-07-15
CN1157408C (zh) 2004-07-14
FI961600A0 (fi) 1996-04-11

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