PT71790B - Process for preparing proinsulin genes and human pre-proinsulin - Google Patents

Process for preparing proinsulin genes and human pre-proinsulin

Info

Publication number
PT71790B
PT71790B PT71790A PT7179080A PT71790B PT 71790 B PT71790 B PT 71790B PT 71790 A PT71790 A PT 71790A PT 7179080 A PT7179080 A PT 7179080A PT 71790 B PT71790 B PT 71790B
Authority
PT
Portugal
Prior art keywords
proinsulin
preparing
genes
human pre
human
Prior art date
Application number
PT71790A
Other languages
English (en)
Other versions
PT71790A (en
Inventor
Graeme Bell
Raymond Louis Pictet
Howard Michael Goodman
William J Rutter
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of PT71790A publication Critical patent/PT71790A/pt
Publication of PT71790B publication Critical patent/PT71790B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
PT71790A 1979-09-12 1980-09-10 Process for preparing proinsulin genes and human pre-proinsulin PT71790B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7519279A 1979-09-12 1979-09-12

Publications (2)

Publication Number Publication Date
PT71790A PT71790A (en) 1980-10-01
PT71790B true PT71790B (en) 1981-07-07

Family

ID=22124154

Family Applications (1)

Application Number Title Priority Date Filing Date
PT71790A PT71790B (en) 1979-09-12 1980-09-10 Process for preparing proinsulin genes and human pre-proinsulin

Country Status (28)

Country Link
EP (1) EP0026598A1 (pt)
JP (1) JP2637393B2 (pt)
KR (1) KR870000501B1 (pt)
AT (1) AT377003B (pt)
AU (1) AU538154B2 (pt)
BE (1) BE885196A (pt)
BG (2) BG41137A3 (pt)
CA (1) CA1180289A (pt)
CZ (2) CZ278883B6 (pt)
DD (3) DD155004A5 (pt)
DK (1) DK385980A (pt)
ES (3) ES8107307A1 (pt)
FI (1) FI802837A (pt)
FR (1) FR2464997B1 (pt)
GR (1) GR70279B (pt)
IE (1) IE52781B1 (pt)
IL (1) IL61041A (pt)
IT (1) IT1129250B (pt)
LU (1) LU82757A1 (pt)
NZ (1) NZ194786A (pt)
PH (1) PH26475A (pt)
PL (1) PL226725A1 (pt)
PT (1) PT71790B (pt)
RO (1) RO80005A (pt)
SK (1) SK621580A3 (pt)
SU (1) SU1491345A3 (pt)
YU (1) YU233480A (pt)
ZA (1) ZA805341B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
US4249952A (en) * 1980-03-03 1981-02-10 Pennsylvania Engineering Corporation Method for producing cement clinker from cement kiln waste dust
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
ZA824218B (en) * 1981-06-29 1983-04-27 Cetus Corp Plasmid for producing human insulin
JPS58183659A (ja) * 1982-03-31 1983-10-26 ジェネテイックス、インスチチュ−ト、インコ−ポレ−テッド 修飾プロインシュリン前駆体、これを暗号化するdna配列およびそれらの産生方法
US5023321A (en) * 1982-12-13 1991-06-11 Howard Florey Institute Of Experimental Physiology & Medicine Molecular cloning and characterization of a further gene sequence coding for human relaxin
NZ206534A (en) * 1982-12-13 1988-05-30 Florey Howard Inst Molecular cloning and characterisation of gene sequence coding for human relaxin
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
EP0247494B1 (en) * 1986-05-20 1996-07-31 The General Hospital Corporation Method for evaluating the effect of a heterologous agent on an animal
ATE386811T1 (de) 1996-04-05 2008-03-15 Novartis Vaccines & Diagnostic Alphaviren-vektors mit eine reduzierte inhibierung der synthese von zellmakromolekülen
AUPP655698A0 (en) * 1998-10-16 1998-11-05 Commonwealth Scientific And Industrial Research Organisation Delivery system for porcine somatotropin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ187300A (en) * 1977-05-27 1982-08-17 Univ California Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism
EP0001931A3 (en) * 1977-11-08 1979-06-13 Genentech, Inc. Synthetic dna, process for preparing it and recombinant microbial cloning vehicle containing such dna
FI783365A (fi) * 1977-11-08 1979-05-09 Genentech Inc Foerfarande foer mikrobipolypeptiduttryck
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
FI792481A (fi) * 1978-08-11 1980-02-12 Univ California Syntes av enkaroytiskt protein genom anvaendning av mikro-organismer

Also Published As

Publication number Publication date
GR70279B (pt) 1982-09-03
DD208989A5 (de) 1984-04-18
ES495030A0 (es) 1981-10-01
RO80005B (ro) 1983-06-30
LU82757A1 (fr) 1981-02-02
ES8300857A1 (es) 1982-11-16
ATA458580A (de) 1984-06-15
ES8305420A1 (es) 1983-04-01
IE52781B1 (en) 1988-03-02
SK278191B6 (en) 1996-03-06
ES503567A0 (es) 1983-04-01
ZA805341B (en) 1982-01-27
SK621580A3 (en) 1996-03-06
AT377003B (de) 1985-01-25
JPS5695199A (en) 1981-08-01
FR2464997A1 (fr) 1981-03-20
BE885196A (fr) 1980-12-31
AU538154B2 (en) 1984-08-02
ES503568A0 (es) 1982-11-16
IT1129250B (it) 1986-06-04
CZ621580A3 (en) 1994-03-16
IT8068405A0 (it) 1980-09-11
RO80005A (ro) 1983-07-07
DK385980A (da) 1981-03-13
IL61041A (en) 1984-02-29
KR830003576A (ko) 1983-06-21
CZ278883B6 (en) 1994-08-17
PH26475A (en) 1992-07-27
CA1180289A (en) 1985-01-02
KR870000501B1 (ko) 1987-03-12
BG41137A3 (en) 1987-04-15
EP0026598A1 (en) 1981-04-08
BG41136A3 (en) 1987-04-15
FR2464997B1 (fr) 1985-05-24
YU233480A (en) 1984-02-29
DD201693A5 (de) 1983-08-03
NZ194786A (en) 1984-02-03
FI802837A (fi) 1981-03-13
CZ548884A3 (en) 1996-08-14
JP2637393B2 (ja) 1997-08-06
IL61041A0 (en) 1980-11-30
ES8107307A1 (es) 1981-10-01
PT71790A (en) 1980-10-01
IE801912L (en) 1981-03-12
DD155004A5 (de) 1982-05-05
SU1491345A3 (ru) 1989-06-30
PL226725A1 (en) 1983-07-18
AU6232480A (en) 1981-03-19

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