PT681573E - Derivados de taxano em c2 e composicoes farmaceuticas que os contem - Google Patents

Derivados de taxano em c2 e composicoes farmaceuticas que os contem

Info

Publication number
PT681573E
PT681573E PT94907959T PT94907959T PT681573E PT 681573 E PT681573 E PT 681573E PT 94907959 T PT94907959 T PT 94907959T PT 94907959 T PT94907959 T PT 94907959T PT 681573 E PT681573 E PT 681573E
Authority
PT
Portugal
Prior art keywords
contain
pharmaceutical compositions
taxan derivatives
derivatives
taxan
Prior art date
Application number
PT94907959T
Other languages
English (en)
Inventor
Robert A Holton
Chunlin Tao
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/010,798 external-priority patent/US5399726A/en
Application filed by Univ Florida State filed Critical Univ Florida State
Publication of PT681573E publication Critical patent/PT681573E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT94907959T 1993-01-29 1994-01-28 Derivados de taxano em c2 e composicoes farmaceuticas que os contem PT681573E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/010,798 US5399726A (en) 1993-01-29 1993-01-29 Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US3485293A 1993-03-22 1993-03-22
US9471593A 1993-07-20 1993-07-20

Publications (1)

Publication Number Publication Date
PT681573E true PT681573E (pt) 2002-11-29

Family

ID=27359309

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94907959T PT681573E (pt) 1993-01-29 1994-01-28 Derivados de taxano em c2 e composicoes farmaceuticas que os contem

Country Status (13)

Country Link
EP (2) EP0681573B1 (pt)
JP (2) JP3452928B2 (pt)
CN (1) CN1125061C (pt)
AT (2) ATE220064T1 (pt)
AU (2) AU685778B2 (pt)
CA (2) CA2155013C (pt)
DE (2) DE69430902T2 (pt)
DK (1) DK0681573T3 (pt)
ES (1) ES2176237T3 (pt)
IL (1) IL108444A0 (pt)
PT (1) PT681573E (pt)
TW (2) TW360646B (pt)
WO (2) WO1994017052A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
IL108443A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C7 taxane derivatives and pharmaceutical compositions containing them
FR2702212B1 (fr) * 1993-03-02 1995-04-07 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
FR2723094A1 (fr) * 1994-07-26 1996-02-02 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2162759A1 (en) * 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
WO1998013359A1 (de) * 1996-09-24 1998-04-02 Marigen S.A. Ultramikroemulsionen aus spontan dispergierbaren konzentraten mit antitumoral und antiviral wirksamen estern von baccatin-iii-verbindungen
EP1067923A4 (en) * 1997-12-31 2002-11-13 Bristol Myers Squibb Co 2-AROYL-4-ACYL PACLITAXEL (TAXEL) ANALOGS
ITMI20021921A1 (it) * 2002-09-10 2004-03-11 Indena Spa Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
AU2005245396A1 (en) * 2004-05-14 2005-12-01 Immunogen, Inc. A facile method for synthesizing baccatin III compounds
US20130090484A1 (en) * 2011-10-11 2013-04-11 Scinopharm Taiwan Ltd. Process for making an intermediate of cabazitaxel
CN104250235B (zh) * 2014-09-24 2016-10-05 江苏红豆杉药业有限公司 一种紫杉醇的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol

Also Published As

Publication number Publication date
ES2176237T3 (es) 2002-12-01
AU6132794A (en) 1994-08-15
JPH10502327A (ja) 1998-03-03
WO1994017052A1 (en) 1994-08-04
DE69430661T2 (de) 2002-10-24
DE69430902T2 (de) 2002-10-24
EP0681573A1 (en) 1995-11-15
EP0681575B1 (en) 2002-05-22
DE69430661D1 (de) 2002-06-27
DE69430902D1 (de) 2002-08-08
ATE217870T1 (de) 2002-06-15
JP3452928B2 (ja) 2003-10-06
CN1125061C (zh) 2003-10-22
EP0681575A4 (pt) 1995-12-13
AU684268B2 (en) 1997-12-11
CA2155013C (en) 2006-04-11
EP0681573A4 (pt) 1995-12-06
CA2155014C (en) 2007-06-26
AU6234094A (en) 1994-08-15
EP0681575A1 (en) 1995-11-15
DK0681573T3 (da) 2002-10-28
TW402598B (en) 2000-08-21
TW360646B (en) 1999-06-11
CA2155013A1 (en) 1994-08-04
EP0681573B1 (en) 2002-07-03
WO1994017051A1 (en) 1994-08-04
JPH08506326A (ja) 1996-07-09
JP3741715B2 (ja) 2006-02-01
CN1101346A (zh) 1995-04-12
IL108444A0 (en) 1994-04-12
ATE220064T1 (de) 2002-07-15
CA2155014A1 (en) 1994-08-04
AU685778B2 (en) 1998-01-29

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