PT632129E - Vectores recombinantes de virus sincicial para utilizacoes medicinais e de diagnostico e processos para a preparacao de vectores recombinantes de virus sincicial - Google Patents

Vectores recombinantes de virus sincicial para utilizacoes medicinais e de diagnostico e processos para a preparacao de vectores recombinantes de virus sincicial

Info

Publication number
PT632129E
PT632129E PT94107918T PT94107918T PT632129E PT 632129 E PT632129 E PT 632129E PT 94107918 T PT94107918 T PT 94107918T PT 94107918 T PT94107918 T PT 94107918T PT 632129 E PT632129 E PT 632129E
Authority
PT
Portugal
Prior art keywords
sincicial
viruses
recombinant
preparation
utilizations
Prior art date
Application number
PT94107918T
Other languages
English (en)
Inventor
Ter Meulen Prof Dr Volker
Rethwilm Dr Axel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT632129E publication Critical patent/PT632129E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/17011—Spumavirus, e.g. chimpanzee foamy virus
    • C12N2740/17022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/17011—Spumavirus, e.g. chimpanzee foamy virus
    • C12N2740/17041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/17043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/80—Vectors comprising a special translation-regulating system from vertebrates
    • C12N2840/85—Vectors comprising a special translation-regulating system from vertebrates mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
PT94107918T 1993-06-03 1994-05-24 Vectores recombinantes de virus sincicial para utilizacoes medicinais e de diagnostico e processos para a preparacao de vectores recombinantes de virus sincicial PT632129E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4318387A DE4318387A1 (de) 1993-06-03 1993-06-03 Rekombinante Foamy Virus Vektoren für medizinische und diagnostische Anwendungen sowie Verfahren zur Herstellung von rekombinanten Foamy Virus Vektoren

Publications (1)

Publication Number Publication Date
PT632129E true PT632129E (pt) 2003-08-29

Family

ID=6489499

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94107918T PT632129E (pt) 1993-06-03 1994-05-24 Vectores recombinantes de virus sincicial para utilizacoes medicinais e de diagnostico e processos para a preparacao de vectores recombinantes de virus sincicial

Country Status (10)

Country Link
US (1) US5646032A (pt)
EP (1) EP0632129B1 (pt)
JP (2) JPH06343477A (pt)
AT (1) ATE237693T1 (pt)
CA (1) CA2124769C (pt)
DE (2) DE4318387A1 (pt)
DK (1) DK0632129T3 (pt)
ES (1) ES2196014T3 (pt)
PT (1) PT632129E (pt)
SI (1) SI0632129T1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707091B1 (fr) 1993-06-30 1997-04-04 Cohen Haguenauer Odile Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes.
FR2727429B1 (fr) 1994-11-30 1997-11-28 Haguenauer Odile Cohen Lignees d'encapsidation et vecteurs d'expression pour la transcomplementation de vecteurs retroviraux defectifs
DE19503082A1 (de) * 1995-02-01 1996-08-08 Univ Ludwigs Albert Gegenstand und Verfahren zur bevorzugt transienten Expression und möglichen Translation spezifischer RNA im cytoplasmatischen Bereich höherer eukaryontischer Zellen
US5888767A (en) * 1996-11-27 1999-03-30 The Johns Hopkins University School Of Medicine Method of using a conditionally replicating viral vector to express a gene
CA2279675A1 (en) 1995-12-15 1997-06-16 Enzo Therapeutics, Inc. Property effecting and/or property exhibiting constructs for localizing a nucleic acid construct within a cell for therapeutic and diagnostic uses
US6492165B1 (en) 1997-02-12 2002-12-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Retrovirus isolated from humans
US5882912A (en) * 1997-02-12 1999-03-16 Center For Disease Control And Prevention Retrovirus isolated from humans
JP3954151B2 (ja) * 1997-03-14 2007-08-08 トランスジエヌ・エス・アー フォーミーウイルスエンベロープタンパク質の発現
AU1325300A (en) 1998-10-27 2000-05-15 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The New retrovirus isolated from humans
DE19858441C2 (de) * 1998-12-17 2001-02-15 Deutsches Krebsforsch FV-Vektoren zur Expression von Fremdgenen in Säugern und deren Verwendung
WO2000041732A1 (en) * 1999-01-19 2000-07-20 The Children's Hospital Of Philadelphia Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
US6800475B1 (en) 1999-06-14 2004-10-05 The United States Of America As Represented By The Department Of Health And Human Services Isolation of a human retrovirus
WO2004003153A2 (en) * 2002-06-27 2004-01-08 The Government Of The United States Of America, Asrepresented By The Secretary Department Of Health And Human Services Centers For Disease Control And Prevention Live replicating spumavirus vector
US20050272650A1 (en) * 2004-02-17 2005-12-08 Mohapatra Shyam S Materials and methods for treatment of inflammatory and cell proliferation disorders
US8071560B2 (en) * 2004-02-17 2011-12-06 University Of South Florida Materials and methods for reducing inflammation by inhibition of the atrial natriuretic peptide receptor
US20080214437A1 (en) * 2002-09-06 2008-09-04 Mohapatra Shyam S Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases
US7655772B2 (en) 2002-09-06 2010-02-02 University Of South Florida Materials and methods for treatment of allergic diseases
WO2005117947A1 (en) * 2004-06-04 2005-12-15 Deutsches Krebsforschungszentrum - Stiftung Des Öffentlichen Rechts - Use of the foamy virus bet protein for inactivating apobec
US10184942B2 (en) 2011-03-17 2019-01-22 University Of South Florida Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
EP3684421A4 (en) * 2017-09-18 2021-08-04 Children's Hospital Medical Center STRONG INSULATOR AND ITS USES IN GENE ADMINISTRATION

Also Published As

Publication number Publication date
DE69432500T2 (de) 2003-11-20
EP0632129B1 (en) 2003-04-16
ATE237693T1 (de) 2003-05-15
CA2124769C (en) 2007-07-10
SI0632129T1 (en) 2003-08-31
CA2124769A1 (en) 1994-12-04
EP0632129A1 (en) 1995-01-04
DE69432500D1 (de) 2003-05-22
US5646032A (en) 1997-07-08
JP2007082562A (ja) 2007-04-05
DK0632129T3 (da) 2003-08-04
ES2196014T3 (es) 2003-12-16
DE4318387A1 (de) 1994-12-08
JPH06343477A (ja) 1994-12-20

Similar Documents

Publication Publication Date Title
PT632129E (pt) Vectores recombinantes de virus sincicial para utilizacoes medicinais e de diagnostico e processos para a preparacao de vectores recombinantes de virus sincicial
ATE79649T1 (de) Herpes simplex-virus als vektor.
WO1995006743A3 (en) Methods and compositions for the large scale production of recombinant adeno-associated virus
GB2255777B (en) Indicator cells and recombinant retroviruses for use in the detection of gene sequences
DK0784693T3 (da) Virusvektorer til genterapi
CA2225278A1 (en) Recombinant mva virus, and the use thereof
CA2066053A1 (en) Recombinant retroviruses delivering vector constructs to target cells
CA2161962A1 (en) Adenovirus vectors for gene therapy
CA2104396A1 (en) Viral particles having altered host range
DE69125925D1 (de) Rekombinante herpes simplex virus impfstoffe und methoden
DE69638196D1 (de) Rekombinantes sendai-virus
ATE366314T1 (de) Infektioese rna virus-klone, vakzine und davon abgeleitete diagnostische assays
DE69114997D1 (de) Von Adeno-assoziierte Viren rekombinante Vektoren.
AU8067698A (en) Chimeric vectors comprising a phage packaging site and a portion derived from a genome of a eukaryotic virus
WO1998055639A3 (fr) Vecteurs adenoviraux recombinants comprenant une sequence d'epissage
EP0261940A3 (en) Pseudorabies vaccines and dna vectors for recombination with pox viruses
WO1994013812A3 (en) Novel entomopoxvirus genes, proteins and methods of use thereof
DE60033180D1 (de) Auf dem rinderimmunschwächevirus (biv) basierte vektoren
DK498387A (da) Virus-dna-sekvens
ATE227775T1 (de) Impfstoff-vektoren von rekombinantem katzen- herpesvirus
Misko et al. Cytotoxic T lymphocyte discrimination between type A Epstein—Barr virus transformants is mapped to an immunodominant epitope in EBNA 3
AU8188187A (en) Viral vector and recombinant DNA coding, in particular, for the p25 protein of the virus that is a causal agent of aids, infected cell culture, protein obtained, vaccine and antibodies obtained
WO1992014818A3 (en) Entomopoxvirus expression system comprising spheroidin or thymidine-kinase sequences
AU5104096A (en) Novel recombinant dna vectors for gene therapy
Leung et al. A direct cloning-expression system for neutralization antigens of herpes simplex viruses.