PT3989972T - Agonistas do recetor de péptido 1 de tipo glucagom - Google Patents
Agonistas do recetor de péptido 1 de tipo glucagomInfo
- Publication number
- PT3989972T PT3989972T PT207395237T PT20739523T PT3989972T PT 3989972 T PT3989972 T PT 3989972T PT 207395237 T PT207395237 T PT 207395237T PT 20739523 T PT20739523 T PT 20739523T PT 3989972 T PT3989972 T PT 3989972T
- Authority
- PT
- Portugal
- Prior art keywords
- glucagon
- peptide
- receptor agonists
- agonists
- receptor
- Prior art date
Links
- 239000003877 glucagon like peptide 1 receptor agonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962868117P | 2019-06-28 | 2019-06-28 | |
| US201962904906P | 2019-09-24 | 2019-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3989972T true PT3989972T (pt) | 2023-12-04 |
Family
ID=71575804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT207395237T PT3989972T (pt) | 2019-06-28 | 2020-06-19 | Agonistas do recetor de péptido 1 de tipo glucagom |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US11655242B2 (pt) |
| EP (2) | EP3989972B1 (pt) |
| JP (1) | JP7256300B2 (pt) |
| KR (1) | KR20220012924A (pt) |
| CN (1) | CN114008033A (pt) |
| AU (1) | AU2020309064B2 (pt) |
| BR (1) | BR112021023923A2 (pt) |
| CA (1) | CA3144055C (pt) |
| CL (1) | CL2021003419A1 (pt) |
| CO (1) | CO2021017433A2 (pt) |
| CR (1) | CR20210599A (pt) |
| DK (1) | DK3989972T3 (pt) |
| DO (1) | DOP2021000273A (pt) |
| EC (1) | ECSP21093576A (pt) |
| FI (1) | FI3989972T3 (pt) |
| HR (1) | HRP20231586T1 (pt) |
| HU (1) | HUE065080T2 (pt) |
| IL (1) | IL288479A (pt) |
| JO (1) | JOP20210337A1 (pt) |
| LT (1) | LT3989972T (pt) |
| MX (1) | MX2021015328A (pt) |
| PE (1) | PE20220590A1 (pt) |
| PL (1) | PL3989972T3 (pt) |
| PT (1) | PT3989972T (pt) |
| RS (1) | RS64940B1 (pt) |
| SI (1) | SI3989972T1 (pt) |
| TW (1) | TWI751585B (pt) |
| WO (1) | WO2020263695A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10954221B2 (en) | 2019-04-12 | 2021-03-23 | Qilu Regor Therapeutics Inc. | GLP-1R agonists and uses thereof |
| AU2020369568B2 (en) * | 2019-10-25 | 2024-03-21 | Gilead Sciences, Inc. | GLP-1R modulating compounds |
| US20230051318A1 (en) | 2019-12-02 | 2023-02-16 | Hyundai Pharm Co., Ltd. | Glp-1 receptor agonist |
| EP4097099A4 (en) | 2020-02-07 | 2023-09-27 | Gasherbrum Bio, Inc. | HETEROCYCLIC GLP-1 AGONISTS |
| WO2021160127A1 (en) * | 2020-02-13 | 2021-08-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| CN115279750A (zh) * | 2020-03-18 | 2022-11-01 | 株式会社Lg化学 | Glp-1受体激动剂、包含该激动剂的药物组合物及其制备方法 |
| IL296336A (en) * | 2020-03-18 | 2022-11-01 | Lg Chemical Ltd | A agonist for the glp-1 receptor, a pharmaceutical preparation containing it and a method for its preparation |
| CA3190163A1 (en) | 2020-08-06 | 2022-02-10 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2022042691A1 (en) | 2020-08-28 | 2022-03-03 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| EP4247804A1 (en) | 2020-11-20 | 2023-09-27 | Gilead Sciences, Inc. | Polyheterocyclic glp-1 r modulating compounds |
| CN115461334A (zh) * | 2020-11-27 | 2022-12-09 | 深圳信立泰药业股份有限公司 | 一种苯并咪唑类衍生物及其制备方法和医药用途 |
| WO2022184849A1 (en) | 2021-03-04 | 2022-09-09 | Les Laboratoires Servier | Glp-1r agonists, uses and pharmaceutical compositions thereof |
| WO2022202864A1 (ja) | 2021-03-24 | 2022-09-29 | 塩野義製薬株式会社 | 縮合環を有するｇｌｐ－１受容体作動薬を含有する医薬組成物 |
| JP2024514259A (ja) * | 2021-04-08 | 2024-03-29 | エルジー・ケム・リミテッド | Ｇｌｐ－１受容体作動薬、それを含む薬学的組成物、およびその製造方法 |
| CR20230495A (es) | 2021-04-21 | 2023-11-30 | Gilead Sciences Inc | Compuestos moduladores del glp-ir carboxibenzimidazólicos. |
| BR112023022836A2 (pt) * | 2021-05-03 | 2024-01-16 | Carmot Therapeutics Inc | Agonistas de receptores de glp-1 benzimidazoíla, composições farmacêuticas que compreendem os mesmos e métodos para seu uso |
| TW202310838A (zh) | 2021-05-20 | 2023-03-16 | 美商美國禮來大藥廠 | 類升糖素肽1受體促效劑 |
| WO2023038039A1 (ja) | 2021-09-08 | 2023-03-16 | 塩野義製薬株式会社 | 抗肥満作用の関与する疾患の予防及び治療用医薬 |
| AU2022358915A1 (en) | 2021-10-05 | 2024-05-09 | Astrazeneca Ab | Certain 2,5-diazabicyclo[4.2.0]octanes as glp-1 receptor modulators |
| WO2023057414A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| WO2023057429A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain 2,5-diazabicyclo[4.2.0]octanes and octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| WO2023111145A1 (en) | 2021-12-16 | 2023-06-22 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| WO2023111144A1 (en) | 2021-12-16 | 2023-06-22 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| WO2023169436A1 (zh) * | 2022-03-08 | 2023-09-14 | 广州市联瑞制药有限公司 | 苯并双环类化合物及其制备方法和应用 |
| WO2024041609A1 (zh) * | 2022-08-24 | 2024-02-29 | 广州市联瑞制药有限公司 | 苯并双环类化合物及其制备方法和应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120053180A1 (en) * | 2010-08-27 | 2012-03-01 | Chemizon, A Division Of Optomagic Co., Ltd. | Cyclohexane analogues as gpr119 agonists |
| AR087451A1 (es) * | 2011-08-17 | 2014-03-26 | Lilly Co Eli | Derivado de 1,2,3,4-tetrahidroquinolina util para tratamiento de diabetes |
| WO2018098781A1 (en) * | 2016-12-01 | 2018-06-07 | Eli Lilly And Company | Pyrrolidinone compounds |
| DK3555064T5 (da) * | 2016-12-16 | 2023-05-01 | Pfizer | GLP-1 receptoragonister og anvendelser deraf |
| TWI707683B (zh) | 2018-06-13 | 2020-10-21 | 美商輝瑞股份有限公司 | Ｇｌｐ－１受體促效劑及其用途 |
| BR112020024956A2 (pt) | 2018-06-15 | 2021-03-09 | Pfizer Inc. | Agonistas de receptor de glp-1 e usos dos mesmos |
| EP3883928A4 (en) | 2018-11-22 | 2022-06-29 | Qilu Regor Therapeutics Inc. | Glp-1r agonists and uses thereof |
| US10954221B2 (en) * | 2019-04-12 | 2021-03-23 | Qilu Regor Therapeutics Inc. | GLP-1R agonists and uses thereof |
| CR20210562A (es) * | 2019-04-12 | 2022-02-18 | Qilu Regor Therapeutics Inc | Agonistas de glp-1r y usos de los mismos |
| WO2021018023A1 (zh) | 2019-08-01 | 2021-02-04 | 济南泰达领创医药技术有限公司 | 小分子glp-1受体调节剂 |
| AU2020369568B2 (en) * | 2019-10-25 | 2024-03-21 | Gilead Sciences, Inc. | GLP-1R modulating compounds |
| CN114728939B (zh) | 2019-11-15 | 2023-12-08 | 日东制药株式会社 | Glp-1受体激动剂及其用途 |
| US20230051318A1 (en) | 2019-12-02 | 2023-02-16 | Hyundai Pharm Co., Ltd. | Glp-1 receptor agonist |
| CN115335374A (zh) | 2020-01-29 | 2022-11-11 | 吉利德科学公司 | Glp-1r调节化合物 |
| WO2021160127A1 (en) | 2020-02-13 | 2021-08-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| IL296336A (en) | 2020-03-18 | 2022-11-01 | Lg Chemical Ltd | A agonist for the glp-1 receptor, a pharmaceutical preparation containing it and a method for its preparation |
| TW202144340A (zh) | 2020-04-03 | 2021-12-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 稠合咪唑類衍生物、其製備方法及其在醫藥上的應用 |
| US20230295154A1 (en) | 2020-04-29 | 2023-09-21 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
-
2020
- 2020-06-17 TW TW109120333A patent/TWI751585B/zh active
- 2020-06-19 EP EP20739523.7A patent/EP3989972B1/en active Active
- 2020-06-19 SI SI202030314T patent/SI3989972T1/sl unknown
- 2020-06-19 MX MX2021015328A patent/MX2021015328A/es unknown
- 2020-06-19 JO JOP/2021/0337A patent/JOP20210337A1/ar unknown
- 2020-06-19 CA CA3144055A patent/CA3144055C/en active Active
- 2020-06-19 PL PL20739523.7T patent/PL3989972T3/pl unknown
- 2020-06-19 DK DK20739523.7T patent/DK3989972T3/da active
- 2020-06-19 HR HRP20231586TT patent/HRP20231586T1/hr unknown
- 2020-06-19 KR KR1020217042363A patent/KR20220012924A/ko not_active Application Discontinuation
- 2020-06-19 AU AU2020309064A patent/AU2020309064B2/en active Active
- 2020-06-19 EP EP23206307.3A patent/EP4302826A3/en active Pending
- 2020-06-19 WO PCT/US2020/038617 patent/WO2020263695A1/en active Application Filing
- 2020-06-19 LT LTEPPCT/US2020/038617T patent/LT3989972T/lt unknown
- 2020-06-19 FI FIEP20739523.7T patent/FI3989972T3/fi active
- 2020-06-19 JP JP2021577551A patent/JP7256300B2/ja active Active
- 2020-06-19 RS RS20231184A patent/RS64940B1/sr unknown
- 2020-06-19 CN CN202080046428.3A patent/CN114008033A/zh active Pending
- 2020-06-19 PT PT207395237T patent/PT3989972T/pt unknown
- 2020-06-19 US US16/906,063 patent/US11655242B2/en active Active
- 2020-06-19 PE PE2021002176A patent/PE20220590A1/es unknown
- 2020-06-19 CR CR20210599A patent/CR20210599A/es unknown
- 2020-06-19 HU HUE20739523A patent/HUE065080T2/hu unknown
- 2020-06-19 BR BR112021023923A patent/BR112021023923A2/pt unknown
-
2021
- 2021-11-28 IL IL288479A patent/IL288479A/en unknown
- 2021-12-20 CO CONC2021/0017433A patent/CO2021017433A2/es unknown
- 2021-12-20 CL CL2021003419A patent/CL2021003419A1/es unknown
- 2021-12-23 DO DO2021000273A patent/DOP2021000273A/es unknown
- 2021-12-28 EC ECSENADI202193576A patent/ECSP21093576A/es unknown
-
2023
- 2023-03-31 US US18/194,155 patent/US20230250092A1/en active Pending
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