PT3515924T - Formas cristalinas - Google Patents

Formas cristalinas

Info

Publication number
PT3515924T
PT3515924T PT177714367T PT17771436T PT3515924T PT 3515924 T PT3515924 T PT 3515924T PT 177714367 T PT177714367 T PT 177714367T PT 17771436 T PT17771436 T PT 17771436T PT 3515924 T PT3515924 T PT 3515924T
Authority
PT
Portugal
Prior art keywords
crystalline forms
crystalline
forms
Prior art date
Application number
PT177714367T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of PT3515924T publication Critical patent/PT3515924T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT177714367T 2016-09-22 2017-09-21 Formas cristalinas PT3515924T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2016072562 2016-09-22

Publications (1)

Publication Number Publication Date
PT3515924T true PT3515924T (pt) 2022-03-11

Family

ID=59923448

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177714367T PT3515924T (pt) 2016-09-22 2017-09-21 Formas cristalinas

Country Status (27)

Country Link
US (4) US10730896B2 (enExample)
EP (2) EP3515924B1 (enExample)
JP (1) JP7097369B2 (enExample)
KR (1) KR102552795B1 (enExample)
CN (1) CN109715639B (enExample)
AU (1) AU2017331930B2 (enExample)
CA (1) CA3037794A1 (enExample)
CL (1) CL2019000728A1 (enExample)
CY (1) CY1125052T1 (enExample)
DK (1) DK3515924T3 (enExample)
EA (1) EA201990723A1 (enExample)
ES (1) ES2908572T3 (enExample)
HR (1) HRP20220234T1 (enExample)
HU (1) HUE057772T2 (enExample)
IL (1) IL265445B2 (enExample)
LT (1) LT3515924T (enExample)
MA (1) MA46266B1 (enExample)
MX (1) MX381590B (enExample)
MY (1) MY193080A (enExample)
PH (1) PH12019500567B1 (enExample)
PL (1) PL3515924T3 (enExample)
PT (1) PT3515924T (enExample)
RS (1) RS62946B1 (enExample)
SI (1) SI3515924T1 (enExample)
TW (1) TWI752086B (enExample)
UA (1) UA124073C2 (enExample)
WO (1) WO2018055016A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3515924T3 (pl) 2016-09-22 2022-04-11 Idorsia Pharmaceuticals Ltd Krystaliczne postacie
BR112019014567A2 (pt) 2017-03-15 2020-02-18 Idorsia Pharmaceuticals Ltd Antagonista do receptor p2y12 ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de éster butílico do ácido
MX2023000601A (es) 2020-07-15 2023-02-13 Idorsia Pharmaceuticals Ltd Composicion farmaceutica acuosa que comprende un antagonista del receptor p2y12.
EP4370525A2 (en) 2021-07-13 2024-05-22 Idorsia Pharmaceuticals Ltd A process for the synthesis of 4-((r)-2-{[6-((s)-3-methoxy-pyrrolidin-1-yl)-2-phenyl- pyrimidine-4-carbonyl]-amino}-3-phosphono-propionyl)-piperazine-1 -carboxylic acid butyl ester

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373586A (en) 1976-12-09 1978-06-30 Mitsubishi Chem Ind Ltd New penicillin derivatives
CA2020437A1 (en) 1989-07-05 1991-01-06 Yoshihide Fuse Cinnamamide derivative
JP2003502314A (ja) 1999-06-14 2003-01-21 イーライ・リリー・アンド・カンパニー 化合物
US6861424B2 (en) 2001-06-06 2005-03-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
EP1578423B1 (en) 2002-12-11 2010-08-18 Bayer Schering Pharma Aktiengesellschaft 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists
EP1611144B1 (en) 2003-04-09 2010-09-15 Wyeth LLC Derivatives of 2-(8,9-dioxo-2,6-diazabicyclo(5.2.0)non-1(7)-en-2-yl)alkyl phosphonic acid and their use as n-methyl-d-aspartate (nmda) recetor antagonists
TW200640877A (en) 2005-04-28 2006-12-01 Actelion Pharmaceuticals Ltd Pyrimidine derivatives
NZ568335A (en) 2005-10-21 2011-07-29 Actelion Pharmaceuticals Ltd Piperazine derivatives as antimalarial agents
CL2007002920A1 (es) 2006-10-13 2008-06-06 Actelion Pharmaceuticals Ltd Compuestos derivados de 2-aminocarbonilpiridina; composicion farmaceutica; y uso para el tratamiento de trastornos vasculares oclusivos.
AR063518A1 (es) 2006-10-25 2009-01-28 Actelion Pharmaceuticals Ltd Derivados 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y su uso para tratar y/o prevenir enfermedades vasculares perifericas viscerales, hepaticas y renales, enfermedades cardiovasculares y enfermedades cerebrovasculares asociados con la agregacion de plaquetas, incluyendo trombosis
JP4785881B2 (ja) 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
MX2009011089A (es) 2007-04-23 2009-10-30 Sanofi Aventis Derivados de quinolina-carboxamida en calidad de antagonistas de p2y12.
HRP20120735T1 (hr) * 2007-11-29 2012-10-31 Actelion Pharmaceuticals Ltd. Derivati fosfonske kiseline i njihova uporaba kao antagonista p2y12 receptora
EP2238127B1 (en) 2007-12-26 2012-08-15 Sanofi Pyrazole-carboxamide derivatives as p2y12 antagonists
WO2009080226A2 (en) 2007-12-26 2009-07-02 Sanofis-Aventis Heterocyclic pyrazole-carboxamides as p2y12 antagonists
AR071653A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2-fenil-4-ciclopropil-pirimidina
AR071652A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2- fenil-piridina substituidos
ES2567311T3 (es) 2009-04-08 2016-04-21 Actelion Pharmaceuticals Ltd. 6-(3-Aza-biciclo[3.1.0]hex-3-il)-2-fenil-pirimidinas como antagonistas del receptor de ADP
JP5536876B2 (ja) 2009-04-22 2014-07-02 アクテリオン ファーマシューティカルズ リミテッド チアゾール誘導体及びp2y12受容体拮抗剤としてのそれらの使用
PL3515924T3 (pl) 2016-09-22 2022-04-11 Idorsia Pharmaceuticals Ltd Krystaliczne postacie
BR112019014567A2 (pt) 2017-03-15 2020-02-18 Idorsia Pharmaceuticals Ltd Antagonista do receptor p2y12 ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de éster butílico do ácido
MX2023000601A (es) 2020-07-15 2023-02-13 Idorsia Pharmaceuticals Ltd Composicion farmaceutica acuosa que comprende un antagonista del receptor p2y12.

Also Published As

Publication number Publication date
JP7097369B2 (ja) 2022-07-07
KR102552795B1 (ko) 2023-07-06
LT3515924T (lt) 2022-03-10
EP3515924A1 (en) 2019-07-31
PH12019500567B1 (en) 2024-01-31
MX2019003093A (es) 2019-07-18
DK3515924T3 (da) 2022-03-21
HRP20220234T1 (hr) 2022-05-13
KR20190052704A (ko) 2019-05-16
US20250163086A1 (en) 2025-05-22
RS62946B1 (sr) 2022-03-31
IL265445A (en) 2019-05-30
SI3515924T1 (sl) 2022-04-29
CY1125052T1 (el) 2024-02-16
MX381590B (es) 2025-03-12
AU2017331930B2 (en) 2021-07-15
US20200017534A1 (en) 2020-01-16
BR112019004845A2 (pt) 2019-06-04
NZ750772A (en) 2023-10-27
CA3037794A1 (en) 2018-03-29
ES2908572T3 (es) 2022-05-03
JP2019529553A (ja) 2019-10-17
MA46266B1 (fr) 2022-02-28
PL3515924T3 (pl) 2022-04-11
US11365209B2 (en) 2022-06-21
EP3981774A1 (en) 2022-04-13
HUE057772T2 (hu) 2022-06-28
MY193080A (en) 2022-09-26
IL265445B1 (en) 2024-01-01
MA46266A (fr) 2019-07-31
CN109715639A (zh) 2019-05-03
WO2018055016A1 (en) 2018-03-29
IL265445B2 (en) 2024-05-01
CL2019000728A1 (es) 2019-07-05
EA201990723A1 (ru) 2019-10-31
US20220275011A1 (en) 2022-09-01
CN109715639B (zh) 2022-04-19
TW201813965A (zh) 2018-04-16
EP3515924B1 (en) 2021-12-15
PH12019500567A1 (en) 2019-11-18
US12227532B2 (en) 2025-02-18
UA124073C2 (uk) 2021-07-14
TWI752086B (zh) 2022-01-11
AU2017331930A1 (en) 2019-03-07
US20210009614A1 (en) 2021-01-14
US10730896B2 (en) 2020-08-04

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