PT3294762T - Constructos de expressão e métodos de modificar geneticamente levedura metilotrófica - Google Patents
Constructos de expressão e métodos de modificar geneticamente levedura metilotróficaInfo
- Publication number
- PT3294762T PT3294762T PT167934207T PT16793420T PT3294762T PT 3294762 T PT3294762 T PT 3294762T PT 167934207 T PT167934207 T PT 167934207T PT 16793420 T PT16793420 T PT 16793420T PT 3294762 T PT3294762 T PT 3294762T
- Authority
- PT
- Portugal
- Prior art keywords
- methods
- expression constructs
- methylotrophic yeast
- genetically engineering
- engineering methylotrophic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562159899P | 2015-05-11 | 2015-05-11 | |
| US201562183074P | 2015-06-22 | 2015-06-22 | |
| US201562185921P | 2015-06-29 | 2015-06-29 | |
| US201562203052P | 2015-08-10 | 2015-08-10 | |
| US201562220366P | 2015-09-18 | 2015-09-18 | |
| US201562222388P | 2015-09-23 | 2015-09-23 | |
| US201562236506P | 2015-10-02 | 2015-10-02 | |
| US201662313491P | 2016-03-25 | 2016-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3294762T true PT3294762T (pt) | 2022-03-21 |
Family
ID=57249545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167934207T PT3294762T (pt) | 2015-05-11 | 2016-05-11 | Constructos de expressão e métodos de modificar geneticamente levedura metilotrófica |
Country Status (21)
| Country | Link |
|---|---|
| US (5) | US10689656B2 (pt) |
| EP (2) | EP4039695A1 (pt) |
| JP (4) | JP6831797B2 (pt) |
| KR (3) | KR102504198B1 (pt) |
| CN (1) | CN107614516A (pt) |
| AU (3) | AU2016262494B2 (pt) |
| BR (1) | BR112017024123A2 (pt) |
| CA (1) | CA2985641A1 (pt) |
| DK (1) | DK3294762T3 (pt) |
| ES (1) | ES2908463T3 (pt) |
| HK (1) | HK1252605A1 (pt) |
| HR (1) | HRP20220299T1 (pt) |
| HU (1) | HUE058104T2 (pt) |
| LT (1) | LT3294762T (pt) |
| MX (3) | MX2017014469A (pt) |
| NZ (1) | NZ737094A (pt) |
| PL (1) | PL3294762T3 (pt) |
| PT (1) | PT3294762T (pt) |
| RS (1) | RS63099B1 (pt) |
| SI (1) | SI3294762T1 (pt) |
| WO (1) | WO2016183163A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2985641A1 (en) | 2015-05-11 | 2016-11-17 | Impossible Foods Inc. | Expression constructs and methods of genetically engineering methylotrophic yeast |
| EP3568408A4 (en) * | 2017-01-13 | 2020-12-16 | Bolt Threads, Inc. | ELASTOMER PROTEINS |
| WO2018140654A1 (en) * | 2017-01-25 | 2018-08-02 | Altius Institute For Biomedical Sciences | Methods and platform of designing genetic editing tools |
| EP3684389A4 (en) | 2017-09-21 | 2021-06-16 | Dana Farber Cancer Institute, Inc. | INSULATION, PRESERVATION, COMPOSITIONS AND USES OF EXTRACTS FROM JUSTICIA PLANTS |
| US11051532B2 (en) | 2017-09-22 | 2021-07-06 | Impossible Foods Inc. | Methods for purifying protein |
| US10221403B1 (en) * | 2018-04-25 | 2019-03-05 | Life Rainbow Biotech Co., Ltd. | Method of preparing zearalenone hydrolase |
| CN108913732B (zh) * | 2018-07-31 | 2022-02-08 | 华东理工大学 | 一种莫纳可林j异源生产的方法及应用 |
| CN111286520B (zh) * | 2018-12-10 | 2021-05-07 | 上海凯赛生物技术股份有限公司 | 用于发酵生产l-赖氨酸的重组dna、菌株及其应用 |
| CN109929769B (zh) * | 2019-03-05 | 2021-07-23 | 天津科技大学 | 一种利用fld1启动子调控黏玉米谷氨酰胺转氨酶表达的重组毕赤酵母菌株及构建方法 |
| CN109749948A (zh) * | 2019-03-05 | 2019-05-14 | 天津科技大学 | 一种利用tef1启动子调控黏玉米谷氨酰胺转氨酶表达的重组毕赤酵母菌株及构建方法 |
| US11427932B2 (en) | 2019-04-17 | 2022-08-30 | Impossible Foods Inc. | Materials and methods for protein production |
| JP2022531140A (ja) | 2019-04-25 | 2022-07-06 | インポッシブル フーズ インコーポレイテッド | ヘム含有タンパク質の作製のための株および方法 |
| WO2021108502A1 (en) | 2019-11-27 | 2021-06-03 | Evelo Biosciences, Inc. | Methods and compositions for culturing hemoglobin-dependent bacteria |
| WO2021140487A1 (en) * | 2020-01-10 | 2021-07-15 | Intron Biotechnology, Inc. | A method for preparing soy leghemoglobin using escherichia coli |
| US10947552B1 (en) | 2020-09-30 | 2021-03-16 | Alpine Roads, Inc. | Recombinant fusion proteins for producing milk proteins in plants |
| AU2021353004A1 (en) | 2020-09-30 | 2023-04-13 | Nobell Foods, Inc. | Recombinant milk proteins and food compositions comprising the same |
| US10894812B1 (en) | 2020-09-30 | 2021-01-19 | Alpine Roads, Inc. | Recombinant milk proteins |
| WO2022072833A2 (en) | 2020-10-02 | 2022-04-07 | Impossible Foods Inc. | Expression constructs and methods of genetically engineering cells |
| WO2022072846A2 (en) | 2020-10-02 | 2022-04-07 | Impossible Foods Inc. | Transgenic plants with altered fatty acid profiles and upregulated heme biosynthesis |
| AU2021391607A1 (en) * | 2020-12-02 | 2023-06-29 | Planeat Foods Pte. Ltd. | Method of producing globin polypeptide recombinantly and meat substitute food product |
| WO2022251166A2 (en) | 2021-05-25 | 2022-12-01 | Evelo Biosciences, Inc. | Bacterial compositions comprising soy hemoglobin |
| AU2022369299A1 (en) | 2021-10-19 | 2024-03-14 | Eat Scifi Inc. | Plant base/animal cell hybrid meat substitute |
| WO2023114395A1 (en) * | 2021-12-16 | 2023-06-22 | Impossible Foods Inc. | A genetic factor to increase expression of recombinant proteins |
| US11931687B2 (en) | 2022-02-15 | 2024-03-19 | Streamline Innovations, Inc. | Gas purification apparatus and method |
| KR20230164436A (ko) | 2022-05-25 | 2023-12-04 | 한화솔루션 주식회사 | 야생형 효모 균주를 이용한 헴 고생산 방법 |
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| JP3794760B2 (ja) | 1996-07-30 | 2006-07-12 | 三井化学株式会社 | フィターゼ生産酵母 |
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| CA2525493C (en) | 2003-04-11 | 2018-10-30 | Ventria Bioscience | Human blood proteins expressed in oryza seeds |
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| EP2175714A4 (en) | 2007-07-10 | 2011-01-26 | Monsanto Technology Llc | TRANSGENIC PLANTS WITH IMPROVED AGRONOMIC CHARACTERISTICS |
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| WO2012083424A1 (en) | 2010-12-21 | 2012-06-28 | The University Of Western Ontario | Novel amino acid linker sequences for ligand immobilization |
| EP2669375B1 (en) | 2011-01-27 | 2018-10-17 | Kaneka Corporation | Yeast of the genus pichia modified to express high levels of a mpp1 homolog and process for producing protein |
| KR102283514B1 (ko) | 2011-07-12 | 2021-07-29 | 임파서블 푸즈 인크. | 소비재를 위한 방법 및 조성물 |
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| ES2763415T3 (es) | 2012-09-19 | 2020-05-28 | Univ Osaka | Vacuna neumocócica que contiene proteína A superficial neumocócica |
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| RS60259B1 (sr) | 2013-09-11 | 2020-06-30 | Impossible Foods Inc | Izlučivanje polipeptida koji obuhvataju hem |
| BR112016022673B1 (pt) | 2014-03-31 | 2021-12-28 | Impossible Foods Inc. | Composição de réplica de carne |
| CA2985641A1 (en) | 2015-05-11 | 2016-11-17 | Impossible Foods Inc. | Expression constructs and methods of genetically engineering methylotrophic yeast |
| US20190292555A1 (en) | 2016-12-02 | 2019-09-26 | Impossible Foods Inc. | Producing recombinant products in contained systems |
| WO2018102721A1 (en) | 2016-12-02 | 2018-06-07 | City Of Hope | Transgenic plants with upregulated heme biosynthesis |
| JP2022531140A (ja) | 2019-04-25 | 2022-07-06 | インポッシブル フーズ インコーポレイテッド | ヘム含有タンパク質の作製のための株および方法 |
-
2016
- 2016-05-11 CA CA2985641A patent/CA2985641A1/en active Pending
- 2016-05-11 KR KR1020207026647A patent/KR102504198B1/ko active IP Right Grant
- 2016-05-11 CN CN201680029580.4A patent/CN107614516A/zh active Pending
- 2016-05-11 MX MX2017014469A patent/MX2017014469A/es unknown
- 2016-05-11 KR KR1020177033598A patent/KR102229968B1/ko active IP Right Grant
- 2016-05-11 KR KR1020237006299A patent/KR20230031993A/ko not_active Application Discontinuation
- 2016-05-11 PT PT167934207T patent/PT3294762T/pt unknown
- 2016-05-11 NZ NZ737094A patent/NZ737094A/en unknown
- 2016-05-11 EP EP22151183.5A patent/EP4039695A1/en active Pending
- 2016-05-11 ES ES16793420T patent/ES2908463T3/es active Active
- 2016-05-11 AU AU2016262494A patent/AU2016262494B2/en active Active
- 2016-05-11 DK DK16793420.7T patent/DK3294762T3/da active
- 2016-05-11 PL PL16793420T patent/PL3294762T3/pl unknown
- 2016-05-11 EP EP16793420.7A patent/EP3294762B1/en active Active
- 2016-05-11 JP JP2017558948A patent/JP6831797B2/ja active Active
- 2016-05-11 LT LTEPPCT/US2016/031797T patent/LT3294762T/lt unknown
- 2016-05-11 SI SI201631500T patent/SI3294762T1/sl unknown
- 2016-05-11 US US15/573,300 patent/US10689656B2/en active Active
- 2016-05-11 HR HRP20220299TT patent/HRP20220299T1/hr unknown
- 2016-05-11 HU HUE16793420A patent/HUE058104T2/hu unknown
- 2016-05-11 WO PCT/US2016/031797 patent/WO2016183163A1/en active Application Filing
- 2016-05-11 RS RS20220256A patent/RS63099B1/sr unknown
- 2016-05-11 BR BR112017024123-4A patent/BR112017024123A2/pt active Search and Examination
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2017
- 2017-08-16 US US15/678,342 patent/US10273492B2/en active Active
- 2017-08-16 US US15/678,891 patent/US9938327B2/en active Active
- 2017-11-10 MX MX2022013540A patent/MX2022013540A/es unknown
- 2017-11-10 MX MX2022006513A patent/MX2022006513A/es unknown
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2018
- 2018-09-06 US US16/123,121 patent/US11319544B2/en active Active
- 2018-09-17 HK HK18111904.2A patent/HK1252605A1/zh unknown
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2019
- 2019-10-17 AU AU2019250216A patent/AU2019250216B2/en active Active
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2020
- 2020-02-03 JP JP2020016038A patent/JP7308160B2/ja active Active
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2021
- 2021-09-30 JP JP2021161491A patent/JP2022025068A/ja active Pending
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2022
- 2022-01-25 US US17/584,028 patent/US20220290166A1/en active Pending
- 2022-03-03 AU AU2022201465A patent/AU2022201465A1/en active Pending
- 2022-11-04 JP JP2022177137A patent/JP2023022042A/ja active Pending
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