PT3234187T - Método para colocação de moleculas de alvo unico num substrato - Google Patents
Método para colocação de moleculas de alvo unico num substratoInfo
- Publication number
- PT3234187T PT3234187T PT158207340T PT15820734T PT3234187T PT 3234187 T PT3234187 T PT 3234187T PT 158207340 T PT158207340 T PT 158207340T PT 15820734 T PT15820734 T PT 15820734T PT 3234187 T PT3234187 T PT 3234187T
- Authority
- PT
- Portugal
- Prior art keywords
- compositions
- substrate
- methods
- single molecular
- molecular placement
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462092171P | 2014-12-15 | 2014-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3234187T true PT3234187T (pt) | 2021-05-26 |
Family
ID=55071188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT158207340T PT3234187T (pt) | 2014-12-15 | 2015-12-14 | Método para colocação de moleculas de alvo unico num substrato |
Country Status (8)
Country | Link |
---|---|
US (2) | US10350570B2 (pt) |
EP (2) | EP3234187B1 (pt) |
CN (2) | CN107223161B (pt) |
DK (1) | DK3234187T3 (pt) |
ES (1) | ES2870097T3 (pt) |
PL (1) | PL3234187T3 (pt) |
PT (1) | PT3234187T (pt) |
WO (1) | WO2016100196A1 (pt) |
Families Citing this family (18)
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ES2625288T3 (es) | 2011-04-15 | 2017-07-19 | The Johns Hopkins University | Sistema de secuenciación segura |
ES2701742T3 (es) | 2012-10-29 | 2019-02-25 | Univ Johns Hopkins | Prueba de Papanicolaou para cánceres de ovario y de endometrio |
EP3234187B1 (en) * | 2014-12-15 | 2021-02-17 | Illumina, Inc. | Method for single molecular placement on a substrate |
US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
US11118206B2 (en) * | 2016-01-13 | 2021-09-14 | The Trustees Of The University Of Pennsylvania | Multiple stage isothermal enzymatic amplification |
US11513076B2 (en) | 2016-06-15 | 2022-11-29 | Ludwig-Maximilians-Universität München | Single molecule detection or quantification using DNA nanotechnology |
WO2018071522A1 (en) * | 2016-10-11 | 2018-04-19 | Life Technologies Corporation | Rapid amplification of nucleic acids |
GB201704754D0 (en) | 2017-01-05 | 2017-05-10 | Illumina Inc | Kinetic exclusion amplification of nucleic acid libraries |
SG11202001010UA (en) | 2017-08-07 | 2020-03-30 | Univ Johns Hopkins | Methods and materials for assessing and treating cancer |
TWI695846B (zh) * | 2018-03-02 | 2020-06-11 | 孫金生物科技實業有限公司 | 固化式組織澄清方法與組合物 |
CN109837277A (zh) * | 2019-03-01 | 2019-06-04 | 深圳生生凡非基因技术有限公司 | 一种cpgk嵌合型启动子、腺相关病毒载体及其应用 |
US11905532B2 (en) * | 2019-06-25 | 2024-02-20 | Massachusetts Institute Of Technology | Compositions and methods for molecular memory storage and retrieval |
TW202138060A (zh) * | 2019-12-18 | 2021-10-16 | 美商伊路米納有限公司 | 晶片上定位顯微鏡 |
BR112022019541A2 (pt) | 2020-03-30 | 2022-11-16 | Illumina Inc | Métodos e composições para preparação de bibliotecas de ácido nucleico |
WO2023004357A1 (en) * | 2021-07-23 | 2023-01-26 | Illumina, Inc. | Methods for preparing substrate surface for dna sequencing |
CN116179668A (zh) * | 2021-11-26 | 2023-05-30 | 复旦大学 | 靶向反应复合物及其在靶向多重检测中的用途 |
CN114807196B (zh) * | 2022-03-30 | 2023-08-15 | 南京农业大学 | 一种追踪土传植物致病菌传播耐药基因的荧光标记方法 |
CN116297415B (zh) * | 2023-05-11 | 2023-08-18 | 细胞生态海河实验室 | 一种protac药物的筛选方法及载体 |
Family Cites Families (45)
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WO1991006678A1 (en) | 1989-10-26 | 1991-05-16 | Sri International | Dna sequencing |
US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
EP0968223B1 (en) | 1997-01-08 | 2016-12-21 | Sigma-Aldrich Co. LLC | Bioconjugation of macromolecules |
US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
US7427678B2 (en) | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
AU4476900A (en) | 1999-04-20 | 2000-11-02 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US6355431B1 (en) | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
EP1368460B1 (en) | 2000-07-07 | 2007-10-31 | Visigen Biotechnologies, Inc. | Real-time sequence determination |
US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
EP2465943A3 (en) * | 2001-03-16 | 2012-10-03 | Kalim Mir | Linear polymer display |
US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
US7375234B2 (en) | 2002-05-30 | 2008-05-20 | The Scripps Research Institute | Copper-catalysed ligation of azides and acetylenes |
EP3002289B1 (en) | 2002-08-23 | 2018-02-28 | Illumina Cambridge Limited | Modified nucleotides for polynucleotide sequencing |
WO2004027025A2 (en) | 2002-09-20 | 2004-04-01 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
US7259258B2 (en) | 2003-12-17 | 2007-08-21 | Illumina, Inc. | Methods of attaching biological compounds to solid supports using triazine |
EP1701785A1 (en) | 2004-01-07 | 2006-09-20 | Solexa Ltd. | Modified molecular arrays |
US7476503B2 (en) | 2004-09-17 | 2009-01-13 | Pacific Biosciences Of California, Inc. | Apparatus and method for performing nucleic acid analysis |
GB0427236D0 (en) | 2004-12-13 | 2005-01-12 | Solexa Ltd | Improved method of nucleotide detection |
CA2611671C (en) | 2005-06-15 | 2013-10-08 | Callida Genomics, Inc. | Single molecule arrays for genetic and chemical analysis |
GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
CN101460953B (zh) | 2006-03-31 | 2012-05-30 | 索雷克萨公司 | 用于合成分析的序列的系统和装置 |
WO2008051530A2 (en) | 2006-10-23 | 2008-05-02 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
EP2677309B9 (en) | 2006-12-14 | 2014-11-19 | Life Technologies Corporation | Methods for sequencing a nucleic acid using large scale FET arrays, configured to measure a limited pH range |
US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
EP2426214A1 (en) * | 2010-09-01 | 2012-03-07 | Koninklijke Philips Electronics N.V. | Method for amplifying nucleic acids |
EP2614156B1 (en) * | 2010-09-07 | 2018-08-01 | The Regents of The University of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
WO2012170936A2 (en) | 2011-06-09 | 2012-12-13 | Illumina, Inc. | Patterned flow-cells useful for nucleic acid analysis |
WO2013012440A2 (en) * | 2011-07-21 | 2013-01-24 | Cornell University | Methods and devices for dna sequencing and molecular diagnostics |
CA3003082C (en) | 2011-10-28 | 2020-12-15 | Illumina, Inc. | Microarray fabrication system and method |
US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
US8895249B2 (en) * | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
US9512422B2 (en) | 2013-02-26 | 2016-12-06 | Illumina, Inc. | Gel patterned surfaces |
WO2014189768A1 (en) * | 2013-05-19 | 2014-11-27 | The Board Of Trustees Of The Leland | Devices and methods for display of encoded peptides, polypeptides, and proteins on dna |
EP3234187B1 (en) * | 2014-12-15 | 2021-02-17 | Illumina, Inc. | Method for single molecular placement on a substrate |
-
2015
- 2015-12-14 EP EP15820734.0A patent/EP3234187B1/en active Active
- 2015-12-14 ES ES15820734T patent/ES2870097T3/es active Active
- 2015-12-14 WO PCT/US2015/065526 patent/WO2016100196A1/en active Application Filing
- 2015-12-14 PT PT158207340T patent/PT3234187T/pt unknown
- 2015-12-14 CN CN201580068109.1A patent/CN107223161B/zh active Active
- 2015-12-14 PL PL15820734T patent/PL3234187T3/pl unknown
- 2015-12-14 US US15/535,695 patent/US10350570B2/en active Active
- 2015-12-14 DK DK15820734.0T patent/DK3234187T3/da active
- 2015-12-14 EP EP21157018.9A patent/EP3882356A1/en active Pending
- 2015-12-14 CN CN202210176285.9A patent/CN114438172A/zh active Pending
-
2019
- 2019-06-06 US US16/433,346 patent/US10960377B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20180141020A1 (en) | 2018-05-24 |
CN107223161B (zh) | 2022-03-22 |
ES2870097T3 (es) | 2021-10-26 |
PL3234187T3 (pl) | 2021-10-25 |
EP3234187B1 (en) | 2021-02-17 |
CN114438172A (zh) | 2022-05-06 |
US10960377B2 (en) | 2021-03-30 |
US20190374923A1 (en) | 2019-12-12 |
US10350570B2 (en) | 2019-07-16 |
EP3882356A1 (en) | 2021-09-22 |
WO2016100196A1 (en) | 2016-06-23 |
EP3234187A1 (en) | 2017-10-25 |
DK3234187T3 (da) | 2021-05-25 |
CN107223161A (zh) | 2017-09-29 |
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