PT3215158T - Apilimod para utilização no tratamento de cancro renal - Google Patents

Apilimod para utilização no tratamento de cancro renal

Info

Publication number
PT3215158T
PT3215158T PT15795318T PT15795318T PT3215158T PT 3215158 T PT3215158 T PT 3215158T PT 15795318 T PT15795318 T PT 15795318T PT 15795318 T PT15795318 T PT 15795318T PT 3215158 T PT3215158 T PT 3215158T
Authority
PT
Portugal
Prior art keywords
apilimod
treatment
renal cancer
renal
cancer
Prior art date
Application number
PT15795318T
Other languages
English (en)
Portuguese (pt)
Inventor
BEEHARRY Neil
Gayle Sophia
LANDRETTE Sean
Beckett Paul
Conrad Chris
Xu Tian
M Rothberg Jonathan
Lichenstein Henri
Original Assignee
Ai Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ai Therapeutics Inc filed Critical Ai Therapeutics Inc
Publication of PT3215158T publication Critical patent/PT3215158T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PT15795318T 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal PT3215158T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462077127P 2014-11-07 2014-11-07

Publications (1)

Publication Number Publication Date
PT3215158T true PT3215158T (pt) 2019-08-23

Family

ID=54548302

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15795318T PT3215158T (pt) 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal

Country Status (16)

Country Link
US (3) US10206910B2 (https=)
EP (2) EP3581184B1 (https=)
JP (1) JP6705828B2 (https=)
KR (1) KR20170098812A (https=)
CN (1) CN107249638B (https=)
AU (1) AU2015342869A1 (https=)
BR (1) BR112017008799A2 (https=)
CA (1) CA2966359A1 (https=)
ES (1) ES2741399T3 (https=)
HU (1) HUE044557T2 (https=)
IL (1) IL251905B (https=)
MX (1) MX377593B (https=)
PL (1) PL3215158T3 (https=)
PT (1) PT3215158T (https=)
RU (1) RU2727802C2 (https=)
WO (1) WO2016073877A1 (https=)

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US10206910B2 (en) 2014-11-07 2019-02-19 Lam Therapeutics, Inc. Apilimod for use in the treatment of renal cancer
US20190015421A1 (en) * 2016-01-21 2019-01-17 Lam Therapeutics, Inc. Biomarkers for Treating Cancer with Apilimod
JP2019528305A (ja) * 2016-08-25 2019-10-10 エイアイ・セラピューティクス・インコーポレーテッド PIKfyve阻害薬を含む組成物およびRANKシグナル伝達の阻害に関連する方法
KR20190067824A (ko) * 2016-10-12 2019-06-17 에이아이 테라퓨틱스, 인코포레이티드 아필리모드 조성물 및 이를 알츠하이머병 치료에 사용하기 위한 방법
US11066410B2 (en) 2017-03-24 2021-07-20 3100 Central Expressway Llc Fused triazolo-pyrimidine compounds having useful pharmaceutical application
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AU2019223014B2 (en) 2018-02-21 2024-10-17 Orphai Therapeutics Inc. Combination therapy with apilimod and glutamatergic agents
US12589097B2 (en) 2018-02-21 2026-03-31 OrphAl Therapeutics Inc. Apilimod compositions and methods of use
WO2021108255A1 (en) 2019-11-25 2021-06-03 The Regents Of The University Of California Long-acting vegf inhibitors for intraocular neovascularization
KR20220140515A (ko) 2020-01-13 2022-10-18 버지 애널리틱스, 인크. 치환된 피라졸로-피리미딘 및 그의 용도
CN114306370A (zh) * 2021-12-31 2022-04-12 北京悦康科创医药科技股份有限公司 反义寡核苷酸在制备治疗肾癌药物中的应用

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Also Published As

Publication number Publication date
MX377593B (es) 2025-03-10
KR20170098812A (ko) 2017-08-30
RU2727802C2 (ru) 2020-07-24
CN107249638B (zh) 2021-05-14
US20190201385A1 (en) 2019-07-04
ES2741399T3 (es) 2020-02-10
BR112017008799A2 (pt) 2017-12-19
RU2017119065A (ru) 2018-12-07
JP2017535601A (ja) 2017-11-30
IL251905B (en) 2021-03-25
MX2017006015A (es) 2017-11-17
EP3215158B1 (en) 2019-05-08
PL3215158T3 (pl) 2019-11-29
HUE044557T2 (hu) 2019-11-28
EP3581184B1 (en) 2021-02-24
AU2015342869A1 (en) 2017-06-15
US20200297706A1 (en) 2020-09-24
CA2966359A1 (en) 2016-05-12
CN107249638A (zh) 2017-10-13
IL251905A0 (en) 2017-06-29
JP6705828B2 (ja) 2020-06-03
WO2016073877A1 (en) 2016-05-12
RU2017119065A3 (https=) 2019-06-05
EP3215158A1 (en) 2017-09-13
US10206910B2 (en) 2019-02-19
EP3581184A1 (en) 2019-12-18
US20170333408A1 (en) 2017-11-23
US11166944B2 (en) 2021-11-09

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