MX2017006015A - Composiciones para usar en el tratamiento de cancer renal. - Google Patents
Composiciones para usar en el tratamiento de cancer renal.Info
- Publication number
- MX2017006015A MX2017006015A MX2017006015A MX2017006015A MX2017006015A MX 2017006015 A MX2017006015 A MX 2017006015A MX 2017006015 A MX2017006015 A MX 2017006015A MX 2017006015 A MX2017006015 A MX 2017006015A MX 2017006015 A MX2017006015 A MX 2017006015A
- Authority
- MX
- Mexico
- Prior art keywords
- apilimod
- renal cancer
- treatment
- methods
- present disclosure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
La presente descripción se refiere a métodos para tratar cáncer renal con apilimod y composiciones y métodos relacionados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462077127P | 2014-11-07 | 2014-11-07 | |
PCT/US2015/059512 WO2016073877A1 (en) | 2014-11-07 | 2015-11-06 | Apilimod for use in the treatment of renal cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017006015A true MX2017006015A (es) | 2017-11-17 |
Family
ID=54548302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017006015A MX2017006015A (es) | 2014-11-07 | 2015-11-06 | Composiciones para usar en el tratamiento de cancer renal. |
Country Status (16)
Country | Link |
---|---|
US (3) | US10206910B2 (es) |
EP (2) | EP3215158B1 (es) |
JP (1) | JP6705828B2 (es) |
KR (1) | KR20170098812A (es) |
CN (1) | CN107249638B (es) |
AU (1) | AU2015342869A1 (es) |
BR (1) | BR112017008799A2 (es) |
CA (1) | CA2966359A1 (es) |
ES (1) | ES2741399T3 (es) |
HU (1) | HUE044557T2 (es) |
IL (1) | IL251905B (es) |
MX (1) | MX2017006015A (es) |
PL (1) | PL3215158T3 (es) |
PT (1) | PT3215158T (es) |
RU (1) | RU2727802C2 (es) |
WO (1) | WO2016073877A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112016017112A2 (pt) | 2014-01-24 | 2017-08-08 | Ai Therapeutics Inc | Composições de apilimod e métodos de uso das mesmas |
ES2734081T3 (es) * | 2014-11-07 | 2019-12-04 | Ai Therapeutics Inc | Apilimod para el uso en el tratamiento de melanoma |
EP3215158B1 (en) | 2014-11-07 | 2019-05-08 | AI Therapeutics, Inc. | Apilimod for use in the treatment of renal cancer |
TW201726142A (zh) * | 2016-01-21 | 2017-08-01 | 藍治療公司 | 用於以阿吡莫德治療癌症的生物標記 |
CA3034453A1 (en) * | 2016-08-25 | 2018-03-01 | AI Therapeutics, Inc. | Compositions comprising pikfyve inhibitors and methods related to inhibition of rank signaling |
MX2019004179A (es) * | 2016-10-12 | 2019-09-02 | Ai Therapeutics Inc | Composiciones de apilimod y metodos para utilizar las mismas en el tratamiento de la enfermedad de alzheimer. |
JP7108680B2 (ja) | 2017-03-24 | 2022-07-28 | ピクサイ インコーポレイテッド | 有用な医薬用途を有する縮合トリアゾロ-ピリミジン化合物 |
CN116059318A (zh) | 2018-01-26 | 2023-05-05 | 加利福尼亚大学董事会 | 用于使用抗vegf剂治疗血管生成病症的方法和组合物 |
CN111801098A (zh) | 2018-02-21 | 2020-10-20 | 人工智能治疗公司 | 使用阿匹莫德和谷氨酸能剂的组合疗法 |
BR112022010113A2 (pt) | 2019-11-25 | 2022-09-06 | Univ California | Inibidores de vegf de longa ação para neovascularização intraocular |
CN114306370A (zh) * | 2021-12-31 | 2022-04-12 | 北京悦康科创医药科技股份有限公司 | 反义寡核苷酸在制备治疗肾癌药物中的应用 |
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DK1921169T3 (da) | 1993-11-12 | 2012-06-04 | Phri Properties Inc | Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kits |
US6693097B2 (en) | 2001-11-30 | 2004-02-17 | Synta Pharmaceuticals Corp. | Pyrimidine compounds |
JP4996261B2 (ja) | 2004-02-06 | 2012-08-08 | エラン ファーマシューティカルズ,インコーポレイテッド | 腫瘍および転移性疾患を処置するための方法および組成物 |
TWI380816B (zh) | 2004-04-13 | 2013-01-01 | Synta Pharmaceuticals Corp | 抑制介白素-12(il-12)生成之二鹽抑制劑 |
EP1791544A4 (en) | 2004-09-08 | 2007-09-12 | Chelsea Therapeutics Inc | DERIVATIVES OF QUINAZOLIN AS METABOLICALLY INERT ANTIFOLIC |
US7923557B2 (en) | 2004-11-10 | 2011-04-12 | Synta Pharmaceuticals Corporation | Process for preparing trisubstituted pyrimidine compounds |
US7863270B2 (en) | 2005-05-13 | 2011-01-04 | Synta Pharmaceuticals Corp. | IL-12 modulatory compounds |
WO2006128129A2 (en) * | 2005-05-26 | 2006-11-30 | Synta Pharmaceuticals Corp. | Method for treating cancer |
AU2006316605B2 (en) | 2005-11-17 | 2012-04-26 | Osi Pharmaceuticals, Inc. | Fused bicyclic mTOR inhibitors |
AR057960A1 (es) | 2005-12-02 | 2007-12-26 | Osi Pharm Inc | Inhibidores de proteina quinasa biciclicos |
EP1981890A2 (en) | 2006-01-25 | 2008-10-22 | OSI Pharmaceuticals, Inc. | UNSATURATED mTOR INHIBITORS |
WO2008008433A2 (en) | 2006-07-12 | 2008-01-17 | University Of Tennessee Research Foundation | Substituted acylanilides and methods of use thereof |
ATE551334T1 (de) | 2007-02-06 | 2012-04-15 | Novartis Ag | Pi3-kinase-hemmer und verfahren zu ihrer verwendung |
RU2438664C2 (ru) | 2007-05-15 | 2012-01-10 | Пирамал Лайф Сайнсиз Лимитед | Синергическая фармацевтическая комбинация для лечения рака |
DE102007036076A1 (de) * | 2007-08-01 | 2009-02-05 | Bayer Healthcare Aktiengesellschaft | Dipeptoid-Produgs und ihre Verwendung |
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JP5258331B2 (ja) | 2008-03-03 | 2013-08-07 | ロート製薬株式会社 | 光安定性が改善されたニューキノロン系抗菌剤含有医薬組成物 |
US20110224223A1 (en) | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
CA2999321A1 (en) | 2008-07-17 | 2010-01-21 | Critical Outcome Technologies Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
EA025443B1 (ru) | 2010-03-08 | 2016-12-30 | Слоан-Кеттеринг Институт Фор Кэнсер | ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРА КИНАЗЫ Cdc7 ГРАНАТИЦИНА B |
WO2011122620A1 (ja) * | 2010-03-29 | 2011-10-06 | 味の素株式会社 | フェニルアラニン誘導体を含有する医薬製剤 |
US8402515B2 (en) | 2010-05-06 | 2013-03-19 | Jonathan Weizman | Apparatus and method for establishing a peer-to-peer communication session with a client device |
WO2011146727A1 (en) | 2010-05-19 | 2011-11-24 | Philip Bosch | Methods of treating interstitial cystitis |
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CA2817931C (en) | 2010-11-19 | 2017-10-31 | Ecole Polytechnique Federale De Lausanne (Epfl) | 2-piperazin-1-yl-4h-1,3-benzothiazin-4-one derivatives and their use for the treatment of mammalian infections |
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SG10201700698WA (en) | 2012-05-15 | 2017-02-27 | Bristol Myers Squibb Co | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
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US9295731B2 (en) | 2013-04-01 | 2016-03-29 | Mark Quang Nguyen | Cleavable drug conjugates, compositions thereof and methods of use |
BR112016017112A2 (pt) * | 2014-01-24 | 2017-08-08 | Ai Therapeutics Inc | Composições de apilimod e métodos de uso das mesmas |
ES2734081T3 (es) | 2014-11-07 | 2019-12-04 | Ai Therapeutics Inc | Apilimod para el uso en el tratamiento de melanoma |
EP3215158B1 (en) | 2014-11-07 | 2019-05-08 | AI Therapeutics, Inc. | Apilimod for use in the treatment of renal cancer |
KR101761573B1 (ko) | 2014-12-29 | 2017-07-26 | 주식회사 인트론바이오테크놀로지 | 신규한 장출혈성 대장균 박테리오파지 Esc-CHP-1 및 이의 장출혈성 대장균 증식 억제 용도 |
WO2016126707A1 (en) | 2015-02-03 | 2016-08-11 | Lam Therapeutics, Inc. | Apilimod compositions and methods for using same |
WO2016160102A1 (en) | 2015-03-31 | 2016-10-06 | Lam Therapeutics, Inc. | Active metabolites of apilimod and uses thereof |
TWI746449B (zh) | 2015-07-20 | 2021-11-21 | 美商Ai治療公司 | 使用阿吡莫德治療癌症之方法 |
EP3817736A4 (en) | 2018-07-05 | 2021-07-28 | Mayo Foundation for Medical Education and Research | PIKFYVE INHIBITORS |
US20210077500A1 (en) | 2019-09-12 | 2021-03-18 | Al Therapeutics, Inc. | Pikfyve inhibitors for cancer therapy |
-
2015
- 2015-11-06 EP EP15795318.3A patent/EP3215158B1/en active Active
- 2015-11-06 RU RU2017119065A patent/RU2727802C2/ru active
- 2015-11-06 BR BR112017008799A patent/BR112017008799A2/pt not_active Application Discontinuation
- 2015-11-06 PT PT15795318T patent/PT3215158T/pt unknown
- 2015-11-06 CN CN201580072608.8A patent/CN107249638B/zh not_active Expired - Fee Related
- 2015-11-06 JP JP2017543329A patent/JP6705828B2/ja not_active Expired - Fee Related
- 2015-11-06 CA CA2966359A patent/CA2966359A1/en not_active Abandoned
- 2015-11-06 EP EP19171060.7A patent/EP3581184B1/en active Active
- 2015-11-06 MX MX2017006015A patent/MX2017006015A/es active IP Right Grant
- 2015-11-06 US US15/524,844 patent/US10206910B2/en active Active
- 2015-11-06 AU AU2015342869A patent/AU2015342869A1/en not_active Abandoned
- 2015-11-06 ES ES15795318T patent/ES2741399T3/es active Active
- 2015-11-06 HU HUE15795318 patent/HUE044557T2/hu unknown
- 2015-11-06 WO PCT/US2015/059512 patent/WO2016073877A1/en active Application Filing
- 2015-11-06 KR KR1020177015388A patent/KR20170098812A/ko not_active Application Discontinuation
- 2015-11-06 PL PL15795318T patent/PL3215158T3/pl unknown
-
2017
- 2017-04-24 IL IL251905A patent/IL251905B/en active IP Right Grant
-
2018
- 2018-12-19 US US16/226,175 patent/US20190201385A1/en not_active Abandoned
-
2019
- 2019-11-26 US US16/695,814 patent/US11166944B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
BR112017008799A2 (pt) | 2017-12-19 |
US20190201385A1 (en) | 2019-07-04 |
CN107249638A (zh) | 2017-10-13 |
IL251905A0 (en) | 2017-06-29 |
HUE044557T2 (hu) | 2019-11-28 |
IL251905B (en) | 2021-03-25 |
US20170333408A1 (en) | 2017-11-23 |
PT3215158T (pt) | 2019-08-23 |
US20200297706A1 (en) | 2020-09-24 |
EP3581184B1 (en) | 2021-02-24 |
CA2966359A1 (en) | 2016-05-12 |
EP3215158A1 (en) | 2017-09-13 |
PL3215158T3 (pl) | 2019-11-29 |
RU2017119065A3 (es) | 2019-06-05 |
US11166944B2 (en) | 2021-11-09 |
CN107249638B (zh) | 2021-05-14 |
US10206910B2 (en) | 2019-02-19 |
AU2015342869A1 (en) | 2017-06-15 |
JP6705828B2 (ja) | 2020-06-03 |
EP3581184A1 (en) | 2019-12-18 |
JP2017535601A (ja) | 2017-11-30 |
KR20170098812A (ko) | 2017-08-30 |
RU2017119065A (ru) | 2018-12-07 |
EP3215158B1 (en) | 2019-05-08 |
ES2741399T3 (es) | 2020-02-10 |
WO2016073877A1 (en) | 2016-05-12 |
RU2727802C2 (ru) | 2020-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC | Change of company name or juridical status |
Owner name: COVESTRO (NETHERLANDS) B.V. |
|
FG | Grant or registration |