PT3019477T - Compostos heterocíclicos e métodos para a sua utilização - Google Patents
Compostos heterocíclicos e métodos para a sua utilizaçãoInfo
- Publication number
- PT3019477T PT3019477T PT148236888T PT14823688T PT3019477T PT 3019477 T PT3019477 T PT 3019477T PT 148236888 T PT148236888 T PT 148236888T PT 14823688 T PT14823688 T PT 14823688T PT 3019477 T PT3019477 T PT 3019477T
- Authority
- PT
- Portugal
- Prior art keywords
- methods
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013902513A AU2013902513A0 (en) | 2013-07-08 | Method of treatment or prophylaxis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3019477T true PT3019477T (pt) | 2021-08-20 |
Family
ID=52279233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148236888T PT3019477T (pt) | 2013-07-08 | 2014-07-08 | Compostos heterocíclicos e métodos para a sua utilização |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9714224B2 (enExample) |
| EP (1) | EP3019477B1 (enExample) |
| JP (1) | JP6505682B2 (enExample) |
| CN (1) | CN105358532B (enExample) |
| ES (1) | ES2883155T3 (enExample) |
| NZ (1) | NZ630908A (enExample) |
| PL (1) | PL3019477T3 (enExample) |
| PT (1) | PT3019477T (enExample) |
| WO (1) | WO2015003223A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6232384B2 (ja) | 2012-01-06 | 2017-11-15 | ノバルティス アーゲー | 複素環式化合物およびその使用方法 |
| ES2898635T3 (es) * | 2015-03-12 | 2022-03-08 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| CN106478502B (zh) * | 2015-08-29 | 2021-04-27 | 上海翰森生物医药科技有限公司 | 1,2,3,4-四氢异喹啉衍生物、其制备方法和应用 |
| KR102132761B1 (ko) * | 2017-06-09 | 2020-07-17 | 산동 단홍 파머수티컬 컴퍼니., 리미티드. | At2r 수용체 길항제로서의 카르복시산 유도체 |
| US11485725B2 (en) | 2017-12-15 | 2022-11-01 | Auransa Inc. | Derivatives of piperlongumine and uses thereof |
| US11384097B2 (en) | 2018-06-19 | 2022-07-12 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Tetrahydroisoquinoline derivative, preparation method therefor and use thereof |
| WO2020012266A1 (en) * | 2018-07-12 | 2020-01-16 | Novartis Ag | Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase |
| WO2020228436A1 (zh) | 2019-05-10 | 2020-11-19 | 浙江海正药业股份有限公司 | 芳环或杂芳环类衍生物及其制备方法和用途 |
| CN111620816B (zh) * | 2020-05-27 | 2023-06-02 | 上海赛默罗生物科技有限公司 | 螺桨烷类衍生物、其制备方法、药物组合物和用途 |
| CN113880825B (zh) * | 2020-07-01 | 2025-03-14 | 浙江海正药业股份有限公司 | 四氢异喹啉类衍生物的盐、其制备方法及其医药应用 |
| CN111777555B (zh) * | 2020-09-04 | 2020-12-01 | 上海赛默罗生物科技有限公司 | 脂肪环烷衍生物、其制备方法、药物组合物和其应用 |
| AU2022318349B2 (en) | 2021-07-30 | 2025-12-18 | Confo Therapeutics N.V. | Compounds for the treatment of pain, in particular neuropathic pain, and/or other diseases or disorders that are associated with at2r and/or at2r mediated signaling |
| CN117603088A (zh) * | 2023-10-28 | 2024-02-27 | 广东工业大学 | 一种基于氨基酸乙酯的芳香醛席夫碱及其在不对称烷基化中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55127373A (en) * | 1979-03-26 | 1980-10-02 | Takeda Chem Ind Ltd | Tetrahydroisoquinoline compound and its preparation |
| US5246943A (en) * | 1992-05-19 | 1993-09-21 | Warner-Lambert Company | Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties |
| US5236934A (en) * | 1992-08-26 | 1993-08-17 | E. I. Du Pont De Nemours And Company | 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders |
| US6649606B1 (en) * | 2001-11-09 | 2003-11-18 | Bristol-Myers Squibb Co. | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
| WO2006055951A2 (en) * | 2004-11-19 | 2006-05-26 | Portola Pharmaceuticals, Inc. | Tetrahydroisoquinolines as factor xa inhibitors |
| NZ555334A (en) | 2004-12-24 | 2010-05-28 | Spinifex Pharm Pty Ltd | Method of treatment or prophylaxis of a neuropathic condition using AT2 receptor antagonist |
| JP5230595B2 (ja) | 2006-03-20 | 2013-07-10 | スピニフェクス ファーマシューティカルズ ピーティーワイ リミテッド | 炎症性疼痛の治療または予防の方法 |
| ES2560327T3 (es) * | 2010-01-19 | 2016-02-18 | Novartis Ag | Métodos y composiciones para una velocidad de conducción nerviosa mejorada |
| NZ605444A (en) | 2010-07-21 | 2015-06-26 | Spinifex Pharm Pty Ltd | Salt and solvates of a tetrahydroisoquinoline derivative |
| JP6232384B2 (ja) | 2012-01-06 | 2017-11-15 | ノバルティス アーゲー | 複素環式化合物およびその使用方法 |
| JP6258867B2 (ja) | 2012-01-25 | 2018-01-10 | ノバルティス アーゲー | 複素環式化合物およびその使用方法 |
| EP2807171B1 (en) | 2012-01-25 | 2020-08-12 | Novartis AG | Heterocyclic compounds and methods for their use |
-
2014
- 2014-07-08 NZ NZ630908A patent/NZ630908A/en unknown
- 2014-07-08 CN CN201480038866.XA patent/CN105358532B/zh not_active Expired - Fee Related
- 2014-07-08 EP EP14823688.8A patent/EP3019477B1/en active Active
- 2014-07-08 PL PL14823688T patent/PL3019477T3/pl unknown
- 2014-07-08 ES ES14823688T patent/ES2883155T3/es active Active
- 2014-07-08 WO PCT/AU2014/050116 patent/WO2015003223A1/en not_active Ceased
- 2014-07-08 PT PT148236888T patent/PT3019477T/pt unknown
- 2014-07-08 US US14/903,166 patent/US9714224B2/en active Active
- 2014-07-08 JP JP2016524633A patent/JP6505682B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US9714224B2 (en) | 2017-07-25 |
| EP3019477B1 (en) | 2021-05-26 |
| ES2883155T3 (es) | 2021-12-07 |
| JP2016525093A (ja) | 2016-08-22 |
| CN105358532B (zh) | 2019-07-23 |
| EP3019477A1 (en) | 2016-05-18 |
| CN105358532A (zh) | 2016-02-24 |
| WO2015003223A1 (en) | 2015-01-15 |
| PL3019477T3 (pl) | 2021-11-22 |
| EP3019477A4 (en) | 2017-01-11 |
| US20160145213A1 (en) | 2016-05-26 |
| JP6505682B2 (ja) | 2019-04-24 |
| NZ630908A (en) | 2017-08-25 |
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