PL3019477T3 - Związki heterocykliczne i sposoby ich stosowania - Google Patents

Związki heterocykliczne i sposoby ich stosowania

Info

Publication number
PL3019477T3
PL3019477T3 PL14823688T PL14823688T PL3019477T3 PL 3019477 T3 PL3019477 T3 PL 3019477T3 PL 14823688 T PL14823688 T PL 14823688T PL 14823688 T PL14823688 T PL 14823688T PL 3019477 T3 PL3019477 T3 PL 3019477T3
Authority
PL
Poland
Prior art keywords
methods
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
PL14823688T
Other languages
English (en)
Polish (pl)
Inventor
Thomas David Mccarthy
Alan Naylor
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013902513A external-priority patent/AU2013902513A0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL3019477T3 publication Critical patent/PL3019477T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL14823688T 2013-07-08 2014-07-08 Związki heterocykliczne i sposoby ich stosowania PL3019477T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2013902513A AU2013902513A0 (en) 2013-07-08 Method of treatment or prophylaxis
PCT/AU2014/050116 WO2015003223A1 (en) 2013-07-08 2014-07-08 Heterocyclic compounds and methods of their use
EP14823688.8A EP3019477B1 (en) 2013-07-08 2014-07-08 Heterocyclic compounds and methods of their use

Publications (1)

Publication Number Publication Date
PL3019477T3 true PL3019477T3 (pl) 2021-11-22

Family

ID=52279233

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14823688T PL3019477T3 (pl) 2013-07-08 2014-07-08 Związki heterocykliczne i sposoby ich stosowania

Country Status (9)

Country Link
US (1) US9714224B2 (enExample)
EP (1) EP3019477B1 (enExample)
JP (1) JP6505682B2 (enExample)
CN (1) CN105358532B (enExample)
ES (1) ES2883155T3 (enExample)
NZ (1) NZ630908A (enExample)
PL (1) PL3019477T3 (enExample)
PT (1) PT3019477T (enExample)
WO (1) WO2015003223A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2800738T (pt) 2012-01-06 2020-06-23 Novartis Ag Compostos heterocíclicos e métodos para a utilização dos mesmos
US10308628B2 (en) * 2015-03-12 2019-06-04 Novartis Ag Heterocyclic compounds and methods for their use
CN106478502B (zh) * 2015-08-29 2021-04-27 上海翰森生物医药科技有限公司 1,2,3,4-四氢异喹啉衍生物、其制备方法和应用
PT3620454T (pt) 2017-06-09 2021-09-10 Shandong Danhong Pharmaceutical Co Ltd Derivado de ácido carboxílico como antagonista do recetor at2r
US11485725B2 (en) 2017-12-15 2022-11-01 Auransa Inc. Derivatives of piperlongumine and uses thereof
US11384097B2 (en) 2018-06-19 2022-07-12 Zhejiang Hisun Pharmaceutical Co., Ltd. Tetrahydroisoquinoline derivative, preparation method therefor and use thereof
WO2020012266A1 (en) * 2018-07-12 2020-01-16 Novartis Ag Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase
CN111620816B (zh) * 2020-05-27 2023-06-02 上海赛默罗生物科技有限公司 螺桨烷类衍生物、其制备方法、药物组合物和用途
CN113880825B (zh) * 2020-07-01 2025-03-14 浙江海正药业股份有限公司 四氢异喹啉类衍生物的盐、其制备方法及其医药应用
CN111777555B (zh) * 2020-09-04 2020-12-01 上海赛默罗生物科技有限公司 脂肪环烷衍生物、其制备方法、药物组合物和其应用
MX2024001155A (es) 2021-07-30 2024-07-01 Confo Therapeutics N V Compuestos para el tratamiento del dolor, en particular el dolor neuropatico, y/u otras enfermedades o trastornos que se asocian con at2r y/o se?alizacion mediada por at2r.
CN117603088A (zh) * 2023-10-28 2024-02-27 广东工业大学 一种基于氨基酸乙酯的芳香醛席夫碱及其在不对称烷基化中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55127373A (en) * 1979-03-26 1980-10-02 Takeda Chem Ind Ltd Tetrahydroisoquinoline compound and its preparation
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
US5236934A (en) * 1992-08-26 1993-08-17 E. I. Du Pont De Nemours And Company 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
WO2003041641A2 (en) * 2001-11-09 2003-05-22 Bristol-Myers Squibb Company Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity
WO2006055951A2 (en) 2004-11-19 2006-05-26 Portola Pharmaceuticals, Inc. Tetrahydroisoquinolines as factor xa inhibitors
NZ555334A (en) 2004-12-24 2010-05-28 Spinifex Pharm Pty Ltd Method of treatment or prophylaxis of a neuropathic condition using AT2 receptor antagonist
AU2007229322B2 (en) * 2006-03-20 2012-04-05 Novartis Ag Method of treatment or prophylaxis inflammatory pain
CA2787173C (en) * 2010-01-19 2018-05-01 Spinifex Pharmaceuticals Pty Ltd Methods and compositions for improved nerve conduction velocity
CN103003244B (zh) * 2010-07-21 2016-04-20 诺华股份有限公司 四氢异喹啉衍生物的盐和溶剂合物
PT2800738T (pt) 2012-01-06 2020-06-23 Novartis Ag Compostos heterocíclicos e métodos para a utilização dos mesmos
US20150011565A1 (en) 2012-01-25 2015-01-08 Spinifex Pharmaceuticals Pty Ltd Heterocyclic Compounds and Methods For Their Use
CN104470930B (zh) 2012-01-25 2017-02-22 诺华股份有限公司 杂环化合物和它们的使用方法

Also Published As

Publication number Publication date
JP2016525093A (ja) 2016-08-22
EP3019477A1 (en) 2016-05-18
JP6505682B2 (ja) 2019-04-24
CN105358532B (zh) 2019-07-23
US20160145213A1 (en) 2016-05-26
EP3019477A4 (en) 2017-01-11
PT3019477T (pt) 2021-08-20
CN105358532A (zh) 2016-02-24
WO2015003223A1 (en) 2015-01-15
ES2883155T3 (es) 2021-12-07
NZ630908A (en) 2017-08-25
EP3019477B1 (en) 2021-05-26
US9714224B2 (en) 2017-07-25

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