PT2910567T - Mutante da quinase iii do ácido asparagínico, células hospedeiras e sua utilização - Google Patents

Mutante da quinase iii do ácido asparagínico, células hospedeiras e sua utilização

Info

Publication number
PT2910567T
PT2910567T PT138463500T PT13846350T PT2910567T PT 2910567 T PT2910567 T PT 2910567T PT 138463500 T PT138463500 T PT 138463500T PT 13846350 T PT13846350 T PT 13846350T PT 2910567 T PT2910567 T PT 2910567T
Authority
PT
Portugal
Prior art keywords
host cells
acid kinase
asparaginic acid
iii mutant
kinase iii
Prior art date
Application number
PT138463500T
Other languages
English (en)
Original Assignee
Cofco Biochemical Anhui Co Ltd
Tianjin Inst Ind Biotechnology Cas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cofco Biochemical Anhui Co Ltd, Tianjin Inst Ind Biotechnology Cas filed Critical Cofco Biochemical Anhui Co Ltd
Publication of PT2910567T publication Critical patent/PT2910567T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004—Aspartate kinase (2.7.2.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT138463500T 2012-10-18 2013-05-16 Mutante da quinase iii do ácido asparagínico, células hospedeiras e sua utilização PT2910567T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210398902.6A CN103773745B (zh) 2012-10-18 2012-10-18 天冬氨酸激酶iii突变体及其宿主细胞和应用

Publications (1)

Publication Number Publication Date
PT2910567T true PT2910567T (pt) 2021-02-05

Family

ID=50487520

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138463500T PT2910567T (pt) 2012-10-18 2013-05-16 Mutante da quinase iii do ácido asparagínico, células hospedeiras e sua utilização

Country Status (7)

Country Link
US (1) US9896734B2 (pt)
EP (1) EP2910567B1 (pt)
JP (1) JP6091629B2 (pt)
CN (2) CN108486082A (pt)
CA (1) CA2888606C (pt)
PT (1) PT2910567T (pt)
WO (1) WO2014059789A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105505894A (zh) * 2014-09-24 2016-04-20 中国科学院天津工业生物技术研究所 天冬氨酸激酶/高丝氨酸脱氢酶突变体及其应用
CN109385417A (zh) * 2017-08-03 2019-02-26 华东理工大学 体内dna无缝组装方法
CN107475281B (zh) * 2017-09-06 2020-10-13 福建农林大学 一种生物转化甲醇代谢途径
CN109295028B (zh) * 2018-11-05 2021-12-17 吉林农业大学 高酶活天冬氨酸激酶突变体、工程菌及该突变体的制备方法
CN114457122B (zh) * 2020-05-13 2023-06-20 安徽华恒生物科技股份有限公司 生产l-缬氨酸的重组微生物及构建方法、应用
CN111944781A (zh) * 2020-09-03 2020-11-17 廊坊梅花生物技术开发有限公司 一种突变的高丝氨酸激酶及其应用
CN113201514B (zh) * 2020-10-16 2022-09-06 中国科学院天津工业生物技术研究所 具有天冬氨酸激酶活性的多肽及其在生产氨基酸中的应用
CN112695036B (zh) * 2021-03-23 2021-07-06 中国科学院天津工业生物技术研究所 一种天冬氨酸激酶基因表达调控序列及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2132414C (en) 1992-03-19 2009-01-27 Saverio Carl Falco Nucleic acid fragments and methods for increasing the lysine and threonine content of the seeds of plants
WO1994011517A1 (en) * 1992-11-10 1994-05-26 Ajinomoto Co., Inc. Process for producing l-threonine by fermentation
DE69629299T2 (de) * 1995-06-13 2004-07-01 Ajinomoto Co., Inc. Prozess für die produktion von l-lysin durch fermentation
JP4088982B2 (ja) * 1996-10-15 2008-05-21 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
EP1477564A2 (en) 1999-07-22 2004-11-17 Incyte Genomics, Inc. Human synthetases
ATE411378T1 (de) 2000-01-21 2008-10-15 Ajinomoto Kk Verfahren zur herstellung von l-lysin
JP2009089603A (ja) 2006-02-02 2009-04-30 Ajinomoto Co Inc メタノール資化性細菌を用いたｌ−リジンの製造法
CN102076856B (zh) * 2008-06-30 2014-12-31 孟山都技术公司 用于提高植物中的氨基酸含量的组合物和方法
US9238829B2 (en) * 2010-10-28 2016-01-19 Adisseo France S.A.S. Method of production of 2,4-dihydroxybutyric acid
JP2014036576A (ja) * 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法

Also Published As

Publication number Publication date
US9896734B2 (en) 2018-02-20
US20150337346A1 (en) 2015-11-26
EP2910567A4 (en) 2016-09-14
EP2910567A1 (en) 2015-08-26
JP2015532111A (ja) 2015-11-09
JP6091629B2 (ja) 2017-03-08
CN108486082A (zh) 2018-09-04
CN103773745A (zh) 2014-05-07
EP2910567B1 (en) 2020-12-16
CA2888606C (en) 2019-01-22
CN103773745B (zh) 2018-03-23
WO2014059789A1 (zh) 2014-04-24
CA2888606A1 (en) 2014-04-24

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