PT2793865T - Composições farmacêuticas de microsferas de triptorrelina - Google Patents

Composições farmacêuticas de microsferas de triptorrelina

Info

Publication number
PT2793865T
PT2793865T PT128607017T PT12860701T PT2793865T PT 2793865 T PT2793865 T PT 2793865T PT 128607017 T PT128607017 T PT 128607017T PT 12860701 T PT12860701 T PT 12860701T PT 2793865 T PT2793865 T PT 2793865T
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
triptorelin microspheres
triptorelin
microspheres
pharmaceutical
Prior art date
Application number
PT128607017T
Other languages
English (en)
Inventor
Sun Kaoxiang
Song Tao
Wang Qilin
Han Jie
Wang Tao
Han Jiangbin
Zhang Jianzhao
Wang Shujiang
Original Assignee
Shandong luye pharmaceutical co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong luye pharmaceutical co ltd filed Critical Shandong luye pharmaceutical co ltd
Publication of PT2793865T publication Critical patent/PT2793865T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
PT128607017T 2011-12-22 2012-12-18 Composições farmacêuticas de microsferas de triptorrelina PT2793865T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201110435894 2011-12-22

Publications (1)

Publication Number Publication Date
PT2793865T true PT2793865T (pt) 2018-03-19

Family

ID=48667698

Family Applications (1)

Application Number Title Priority Date Filing Date
PT128607017T PT2793865T (pt) 2011-12-22 2012-12-18 Composições farmacêuticas de microsferas de triptorrelina

Country Status (8)

Country Link
US (1) US20140356442A1 (pt)
EP (1) EP2793865B1 (pt)
CN (1) CN104010629B (pt)
ES (1) ES2662927T3 (pt)
HU (1) HUE037678T2 (pt)
PL (1) PL2793865T3 (pt)
PT (1) PT2793865T (pt)
WO (1) WO2013091283A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523605A (zh) * 2014-12-30 2015-04-22 北京博恩特药业有限公司 一种曲普瑞林微球及其制备方法与应用
CN105169366B (zh) * 2015-08-19 2018-05-22 丽珠医药集团股份有限公司 一种醋酸曲普瑞林缓释微球的制备方法
CN110859811B (zh) * 2019-12-05 2021-12-07 北京博恩特药业有限公司 药物缓释组合物及制备方法
CN112156170B (zh) * 2020-11-03 2022-10-21 北京康欣东弘医药科技有限公司 可供皮下注射的曲普瑞林缓释微球及其制备方法和用途
CN112675132B (zh) * 2020-12-28 2022-06-21 浙江圣兆药物科技股份有限公司 一种窄粒径分布的曲普瑞林微球的制备方法
CN116327712A (zh) * 2023-03-30 2023-06-27 北京博恩特药业有限公司 一种醋酸曲普瑞林缓释微球及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270320A1 (en) * 1998-04-28 1999-10-28 Patricia Lee Brubaker Novel microsphere composition
CN1194688C (zh) * 2001-07-03 2005-03-30 山东绿叶制药股份有限公司 石杉碱甲及其衍生物或其盐的注射用缓释微球及其制备方法
KR20040066548A (ko) * 2003-01-20 2004-07-27 코오롱제약주식회사 생리활성펩타이드의 국소투여용 서방성 마이크로스피어 및그 제조방법
KR100466637B1 (ko) * 2003-06-26 2005-01-13 주식회사 펩트론 서방성 미립구의 혼합 제형을 연속한 단일 공정으로제조하는 방법
CN1876173A (zh) * 2005-06-06 2006-12-13 中国人民解放军军事医学科学院毒物药物研究所 胸腺五肽注射用缓释微球制剂及其制备方法
CN101627966A (zh) * 2008-07-17 2010-01-20 蚌埠丰原医药科技发展有限公司 丙氨瑞林缓释微球注射剂的制备方法
CN102048699B (zh) * 2009-11-03 2012-11-07 长春金赛药业有限责任公司 一种注射用醋酸曲普瑞林的缓释微球的制备方法

Also Published As

Publication number Publication date
PL2793865T3 (pl) 2018-07-31
WO2013091283A1 (en) 2013-06-27
HUE037678T2 (hu) 2018-09-28
US20140356442A1 (en) 2014-12-04
EP2793865B1 (en) 2018-01-31
CN104010629A (zh) 2014-08-27
EP2793865A4 (en) 2015-06-17
CN104010629B (zh) 2015-07-08
EP2793865A1 (en) 2014-10-29
ES2662927T3 (es) 2018-04-10

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