PT2760882T - Aumento do rendimento de partícula semelhante a vírus em plantas - Google Patents

Aumento do rendimento de partícula semelhante a vírus em plantas

Info

Publication number
PT2760882T
PT2760882T PT128365459T PT12836545T PT2760882T PT 2760882 T PT2760882 T PT 2760882T PT 128365459 T PT128365459 T PT 128365459T PT 12836545 T PT12836545 T PT 12836545T PT 2760882 T PT2760882 T PT 2760882T
Authority
PT
Portugal
Prior art keywords
plants
particle yield
increased virus
virus
increased
Prior art date
Application number
PT128365459T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Medicago Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicago Inc filed Critical Medicago Inc
Publication of PT2760882T publication Critical patent/PT2760882T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16223—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16251—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PT128365459T 2011-09-30 2012-09-28 Aumento do rendimento de partícula semelhante a vírus em plantas PT2760882T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161541780P 2011-09-30 2011-09-30

Publications (1)

Publication Number Publication Date
PT2760882T true PT2760882T (pt) 2023-08-07

Family

ID=47994080

Family Applications (1)

Application Number Title Priority Date Filing Date
PT128365459T PT2760882T (pt) 2011-09-30 2012-09-28 Aumento do rendimento de partícula semelhante a vírus em plantas

Country Status (27)

Country Link
US (1) US11155581B2 (cs)
EP (2) EP2760882B1 (cs)
JP (1) JP6248040B2 (cs)
KR (1) KR101974017B1 (cs)
CN (2) CN116218900A (cs)
AU (1) AU2012315421C1 (cs)
BR (1) BR112014007474A2 (cs)
CA (1) CA2850407C (cs)
DK (1) DK2760882T5 (cs)
ES (1) ES2951259T3 (cs)
FI (1) FI2760882T3 (cs)
HR (1) HRP20230695T1 (cs)
HU (1) HUE062759T2 (cs)
IL (1) IL231587B (cs)
IN (1) IN2014CN03077A (cs)
MX (2) MX358883B (cs)
MY (1) MY184072A (cs)
NZ (1) NZ622731A (cs)
PH (1) PH12014500640A1 (cs)
PL (1) PL2760882T3 (cs)
PT (1) PT2760882T (cs)
RU (1) RU2682752C2 (cs)
SG (2) SG10201708052XA (cs)
SI (1) SI2760882T1 (cs)
TW (1) TWI700368B (cs)
WO (1) WO2013044390A1 (cs)
ZA (1) ZA201403059B (cs)

Families Citing this family (10)

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US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
MX358883B (es) 2011-09-30 2018-08-31 Medicago Inc Aumentar el rendimiento de particulas similares a virus en plantas.
ES2803508T3 (es) * 2013-03-28 2021-01-27 Medicago Inc Producción de partículas similares al virus de la gripe en plantas
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
AU2015205805B2 (en) * 2014-01-10 2020-11-12 Aramis Biotechnologies Inc. CPMV enhancer elements
AU2015234595B2 (en) * 2014-03-27 2021-03-25 Medicago Inc. Modified CPMV enhancer elements
EP3765618A4 (en) * 2018-03-14 2022-01-05 Medicago Inc. PLANT EXPRESSION ACTIVATOR
TW202016308A (zh) * 2018-06-27 2020-05-01 加拿大商苜蓿股份有限公司 流感病毒血球凝集素突變體
BR112021017899A2 (pt) * 2019-03-14 2021-12-21 Medicago Inc Intensificador de expressão vegetal endógeno
WO2021236908A2 (en) * 2020-05-20 2021-11-25 Biomarin Pharmaceutical Inc. Use of regulatory proteins for the production of adeno-associated virus

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MX358883B (es) 2011-09-30 2018-08-31 Medicago Inc Aumentar el rendimiento de particulas similares a virus en plantas.
JP6205359B2 (ja) 2012-07-23 2017-09-27 有限会社生物資源研究所 ワクチン
ES2803508T3 (es) 2013-03-28 2021-01-27 Medicago Inc Producción de partículas similares al virus de la gripe en plantas

Also Published As

Publication number Publication date
MX358883B (es) 2018-08-31
SG11201400712VA (en) 2014-04-28
SI2760882T1 (sl) 2023-10-30
SG10201708052XA (en) 2017-11-29
FI2760882T3 (fi) 2023-07-17
AU2012315421C1 (en) 2019-12-05
HK1200179A1 (en) 2015-07-31
DK2760882T3 (da) 2023-07-03
IL231587A0 (en) 2014-05-28
ZA201403059B (en) 2019-07-31
EP2760882A1 (en) 2014-08-06
PL2760882T3 (pl) 2023-09-11
IL231587B (en) 2020-06-30
BR112014007474A2 (pt) 2017-04-04
KR101974017B1 (ko) 2019-04-30
CA2850407A1 (en) 2013-04-04
MX2014003776A (es) 2014-08-21
CN116218900A (zh) 2023-06-06
AU2012315421A1 (en) 2014-04-10
HUE062759T2 (hu) 2023-12-28
US20150104480A1 (en) 2015-04-16
CA2850407C (en) 2021-11-23
TW201329235A (zh) 2013-07-16
JP2014530006A (ja) 2014-11-17
EP3626733B1 (en) 2024-01-24
RU2682752C2 (ru) 2019-03-21
JP6248040B2 (ja) 2017-12-13
HRP20230695T1 (hr) 2023-12-22
EP2760882B1 (en) 2023-05-24
EP3626733A1 (en) 2020-03-25
US11155581B2 (en) 2021-10-26
TWI700368B (zh) 2020-08-01
RU2014116371A (ru) 2015-11-10
IN2014CN03077A (cs) 2015-07-03
PH12014500640A1 (en) 2014-05-05
NZ622731A (en) 2016-04-29
WO2013044390A1 (en) 2013-04-04
CN103930435A (zh) 2014-07-16
DK2760882T5 (da) 2024-06-24
MX2018006627A (es) 2020-11-12
MY184072A (en) 2021-03-17
AU2012315421B2 (en) 2017-10-19
ES2951259T3 (es) 2023-10-19
EP2760882A4 (en) 2015-06-10
KR20140068260A (ko) 2014-06-05

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