PT2748605T - Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal - Google Patents
Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renalInfo
- Publication number
- PT2748605T PT2748605T PT12832845T PT12832845T PT2748605T PT 2748605 T PT2748605 T PT 2748605T PT 12832845 T PT12832845 T PT 12832845T PT 12832845 T PT12832845 T PT 12832845T PT 2748605 T PT2748605 T PT 2748605T
- Authority
- PT
- Portugal
- Prior art keywords
- renal
- prognosis
- diagnosis
- compositions
- methods
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161528003P | 2011-08-26 | 2011-08-26 | |
| US201161528000P | 2011-08-26 | 2011-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2748605T true PT2748605T (pt) | 2019-05-03 |
Family
ID=47914751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT12832845T PT2748605T (pt) | 2011-08-26 | 2012-08-24 | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9459261B2 (enExample) |
| EP (2) | EP2748605B1 (enExample) |
| JP (2) | JP2014529073A (enExample) |
| KR (1) | KR20140074307A (enExample) |
| CN (2) | CN103874923B (enExample) |
| AU (1) | AU2012312907A1 (enExample) |
| BR (1) | BR112014004389A2 (enExample) |
| CA (1) | CA2846602A1 (enExample) |
| EA (1) | EA201490384A1 (enExample) |
| ES (1) | ES2721907T3 (enExample) |
| IN (1) | IN2014MN00377A (enExample) |
| MX (1) | MX346096B (enExample) |
| PL (1) | PL2748605T4 (enExample) |
| PT (1) | PT2748605T (enExample) |
| TR (1) | TR201903235T4 (enExample) |
| WO (1) | WO2013043310A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ628843A (en) | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| WO2011162821A1 (en) | 2010-06-23 | 2011-12-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2721907T3 (es) * | 2011-08-26 | 2019-08-06 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA3158996C (en) | 2013-01-17 | 2024-06-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11261257B2 (en) | 2013-01-28 | 2022-03-01 | Diasorin S.P.A. | Methods for detecting 1,25-dihydroxyvitamin D and related antibodies |
| DK2759550T3 (en) | 2013-01-28 | 2018-11-26 | Diasorin S P A | Method and kit for detecting vitamin 1,25-dihydroxy-D and related antibodies |
| US10983136B2 (en) * | 2013-01-28 | 2021-04-20 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker |
| CN105917229B (zh) | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| MX388231B (es) | 2014-10-20 | 2025-03-19 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal. |
| CA2973653A1 (en) * | 2015-01-18 | 2016-07-21 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker |
| WO2016164854A1 (en) * | 2015-04-09 | 2016-10-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN105466984B (zh) * | 2016-01-14 | 2018-12-28 | 郑以山 | 用于肾脏非显性损伤的预警装置及其使用方法 |
| AU2017277305A1 (en) | 2016-06-06 | 2018-12-20 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| EP4063853A1 (en) | 2017-01-12 | 2022-09-28 | Astute Medical, Inc. | Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN110709103B (zh) | 2017-04-05 | 2024-02-02 | 机敏医药股份有限公司 | 用于生物学样品中具有改善的性能的timp2的测定法 |
| CN112384807A (zh) | 2018-05-24 | 2021-02-19 | 雷尼布斯治疗公司 | 治疗有风险患有肾损伤和肾衰竭的患者的方法 |
| CN109251956A (zh) * | 2018-09-18 | 2019-01-22 | 青岛大学 | 糖尿病大鼠胰岛内MyD88 mRNA表达及黄芪的调节作用 |
| WO2020092909A1 (en) * | 2018-11-02 | 2020-05-07 | Prevencio, Inc. | Prognostic and diagnostic methods for risk of acute kidney injury |
| CN114113575B (zh) * | 2020-08-28 | 2023-06-02 | 菲鹏生物股份有限公司 | 标记复合物及其制备方法与应用 |
| CN116434960B (zh) * | 2023-06-13 | 2023-10-13 | 中国人民解放军总医院 | 一种心源性休克临床决策支持系统、设备及可存储介质 |
| WO2025033619A1 (ko) * | 2023-08-07 | 2025-02-13 | 경상국립대학교병원 | 신 대체요법 개시 결정을 위한 정보 제공 방법 및 이의 결정을 위한 말기 신질환 진단용 조성물 |
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| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| WO1992005282A1 (en) | 1990-09-14 | 1992-04-02 | Biosite Diagnostics, Inc. | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| ATE177841T1 (de) | 1991-04-10 | 1999-04-15 | Biosite Diagnostics Inc | ''crosstalk''- oder übersprech-inhibitoren und ihre verwendung |
| EP0579767B1 (en) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Novel conjugates and assays for simultaneous detection of multiple ligands |
| US5324634A (en) * | 1992-03-31 | 1994-06-28 | The Research Foundation Of State University Of New York | Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer |
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| EP2360475B1 (en) * | 2003-03-27 | 2019-10-02 | Children's Hospital Medical Center | A method and kit for detecting the early onset of renal tubular cell injury |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| US7560244B2 (en) * | 2003-06-04 | 2009-07-14 | Joslin Diabetes Center, Inc. | Method of evaluating a subject for risk or predisposition of reduced renal function over time |
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| WO2007144781A2 (en) * | 2006-04-21 | 2007-12-21 | Diagnotech Pty. Ltd. | Diagnostic methods and kits utilizing antibodies for metalloproteases |
| EP2479568B1 (en) * | 2007-03-26 | 2015-01-07 | Novartis AG | Predictive renal safety biomarkers and biomarker signatures to monitor kidney function |
| US20100304413A1 (en) * | 2007-11-15 | 2010-12-02 | Lars Otto Uttenthal | Diagnostic use of individual molecular forms of a biomarker |
| KR20100122495A (ko) | 2008-02-29 | 2010-11-22 | 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 | 급성 신장 장해 및 예후 추정용 바이오마커 및 그 용도 |
| NZ610356A (en) * | 2008-08-28 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US9057735B2 (en) * | 2008-08-29 | 2015-06-16 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ628843A (en) * | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2913676A1 (en) * | 2008-11-10 | 2015-09-02 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US9229010B2 (en) * | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20120129265A1 (en) * | 2009-06-02 | 2012-05-24 | Biocrates Life Sciences Ag | New biomarkers for assessing kidney diseases |
| JP5827226B2 (ja) * | 2009-08-07 | 2015-12-02 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| NZ598741A (en) * | 2009-09-18 | 2013-07-26 | Astute Medical Inc | Methods and composition for diagnosis and prognosis of renal injury and renal failure by performing assays to detect metalloproteinase inhibitor 4 on a body fluid sample |
| MX2009012633A (es) | 2009-11-23 | 2011-05-24 | Univ Mexico Nacional Autonoma | Metodo de diagnostico para detectar la lesion renal aguda a traves del uso de la proteina de choque termico de 72 kda como un biomarcador sensible. |
| JP5763098B2 (ja) * | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| EP2539712A4 (en) | 2010-02-26 | 2013-09-18 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| ES2721907T3 (es) * | 2011-08-26 | 2019-08-06 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
-
2012
- 2012-08-24 ES ES12832845T patent/ES2721907T3/es active Active
- 2012-08-24 WO PCT/US2012/052298 patent/WO2013043310A1/en not_active Ceased
- 2012-08-24 EA EA201490384A patent/EA201490384A1/ru unknown
- 2012-08-24 IN IN377MUN2014 patent/IN2014MN00377A/en unknown
- 2012-08-24 MX MX2014002146A patent/MX346096B/es active IP Right Grant
- 2012-08-24 PL PL12832845T patent/PL2748605T4/pl unknown
- 2012-08-24 US US14/241,005 patent/US9459261B2/en active Active
- 2012-08-24 EP EP12832845.7A patent/EP2748605B1/en active Active
- 2012-08-24 EP EP18209718.8A patent/EP3489690A1/en active Pending
- 2012-08-24 PT PT12832845T patent/PT2748605T/pt unknown
- 2012-08-24 CN CN201280049909.5A patent/CN103874923B/zh active Active
- 2012-08-24 CA CA2846602A patent/CA2846602A1/en not_active Abandoned
- 2012-08-24 JP JP2014527328A patent/JP2014529073A/ja active Pending
- 2012-08-24 AU AU2012312907A patent/AU2012312907A1/en not_active Abandoned
- 2012-08-24 TR TR2019/03235T patent/TR201903235T4/tr unknown
- 2012-08-24 BR BR112014004389A patent/BR112014004389A2/pt not_active IP Right Cessation
- 2012-08-24 KR KR1020147007890A patent/KR20140074307A/ko not_active Withdrawn
- 2012-08-24 CN CN201610804095.1A patent/CN106443011A/zh active Pending
-
2016
- 2016-10-03 US US15/284,197 patent/US9784750B2/en active Active
- 2016-10-19 JP JP2016204848A patent/JP2017032586A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012312907A1 (en) | 2014-03-13 |
| JP2014529073A (ja) | 2014-10-30 |
| US9784750B2 (en) | 2017-10-10 |
| EP3489690A1 (en) | 2019-05-29 |
| WO2013043310A1 (en) | 2013-03-28 |
| PL2748605T3 (pl) | 2019-08-30 |
| EP2748605A1 (en) | 2014-07-02 |
| EP2748605A4 (en) | 2015-12-02 |
| MX2014002146A (es) | 2014-08-21 |
| NZ706242A (en) | 2016-07-29 |
| MX346096B (es) | 2017-03-07 |
| US20170016917A1 (en) | 2017-01-19 |
| US9459261B2 (en) | 2016-10-04 |
| NZ621716A (en) | 2016-04-29 |
| ES2721907T3 (es) | 2019-08-06 |
| EP2748605B1 (en) | 2018-12-05 |
| CN103874923B (zh) | 2016-09-14 |
| EA201490384A1 (ru) | 2014-08-29 |
| IN2014MN00377A (enExample) | 2015-06-19 |
| JP2017032586A (ja) | 2017-02-09 |
| CN106443011A (zh) | 2017-02-22 |
| US20140213477A1 (en) | 2014-07-31 |
| TR201903235T4 (tr) | 2019-03-21 |
| PL2748605T4 (pl) | 2019-08-30 |
| KR20140074307A (ko) | 2014-06-17 |
| CA2846602A1 (en) | 2013-03-28 |
| BR112014004389A2 (pt) | 2017-03-28 |
| CN103874923A (zh) | 2014-06-18 |
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