ES2721907T3 - Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal - Google Patents
Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal Download PDFInfo
- Publication number
- ES2721907T3 ES2721907T3 ES12832845T ES12832845T ES2721907T3 ES 2721907 T3 ES2721907 T3 ES 2721907T3 ES 12832845 T ES12832845 T ES 12832845T ES 12832845 T ES12832845 T ES 12832845T ES 2721907 T3 ES2721907 T3 ES 2721907T3
- Authority
- ES
- Spain
- Prior art keywords
- renal
- prognosis
- diagnosis
- compositions
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 206010061481 Renal injury Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
- 101000573945 Coccidioides posadasii (strain C735) Neutral protease 2 homolog MEP2 Proteins 0.000 abstract 2
- 102000000422 Matrix Metalloproteinase 3 Human genes 0.000 abstract 2
- 108010016160 Matrix Metalloproteinase 3 Proteins 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Pregnancy & Childbirth (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161528003P | 2011-08-26 | 2011-08-26 | |
| US201161528000P | 2011-08-26 | 2011-08-26 | |
| PCT/US2012/052298 WO2013043310A1 (en) | 2011-08-26 | 2012-08-24 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2721907T3 true ES2721907T3 (es) | 2019-08-06 |
Family
ID=47914751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12832845T Active ES2721907T3 (es) | 2011-08-26 | 2012-08-24 | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9459261B2 (enExample) |
| EP (2) | EP2748605B1 (enExample) |
| JP (2) | JP2014529073A (enExample) |
| KR (1) | KR20140074307A (enExample) |
| CN (2) | CN106443011A (enExample) |
| AU (1) | AU2012312907A1 (enExample) |
| BR (1) | BR112014004389A2 (enExample) |
| CA (1) | CA2846602A1 (enExample) |
| EA (1) | EA201490384A1 (enExample) |
| ES (1) | ES2721907T3 (enExample) |
| IN (1) | IN2014MN00377A (enExample) |
| MX (1) | MX346096B (enExample) |
| PL (1) | PL2748605T4 (enExample) |
| PT (1) | PT2748605T (enExample) |
| TR (1) | TR201903235T4 (enExample) |
| WO (1) | WO2013043310A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3783363A1 (en) | 2008-10-21 | 2021-02-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EA201290387A1 (ru) | 2009-12-20 | 2013-02-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| EP2585827A4 (en) | 2010-06-23 | 2013-12-04 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency |
| WO2013043310A1 (en) * | 2011-08-26 | 2013-03-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2788759B1 (en) | 2011-12-08 | 2019-02-20 | Astute Medical, Inc. | Methods and uses for diagnosis of renal injury and renal failure |
| EP3734280B8 (en) | 2013-01-17 | 2022-08-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US10983136B2 (en) * | 2013-01-28 | 2021-04-20 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker |
| WO2016113720A1 (en) * | 2015-01-18 | 2016-07-21 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker |
| US11261257B2 (en) | 2013-01-28 | 2022-03-01 | Diasorin S.P.A. | Methods for detecting 1,25-dihydroxyvitamin D and related antibodies |
| ES2696075T3 (es) | 2013-01-28 | 2019-01-14 | Diasorin S P A | Procedimiento y kit para detectar 1,25-dihidroxivitamina D y anticuerpos relacionados |
| WO2015084939A1 (en) | 2013-12-03 | 2015-06-11 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| PT3210018T (pt) | 2014-10-20 | 2021-10-04 | Astute Medical Inc | Métodos e composições para o diagnóstico e prognóstico de lesão renal e insuficiência renal |
| WO2016164854A1 (en) * | 2015-04-09 | 2016-10-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN105466984B (zh) * | 2016-01-14 | 2018-12-28 | 郑以山 | 用于肾脏非显性损伤的预警装置及其使用方法 |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| MX2019008260A (es) | 2017-01-12 | 2020-01-27 | Astute Medical Inc | Metodos y composiciones para la evaluacion y tratamiento de lesion renal e insuficiencia renal con base en la medicion del ligando 14 de quimiocina de la porcion c-c. |
| WO2018145117A1 (en) | 2017-02-06 | 2018-08-09 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP7315466B2 (ja) | 2017-04-05 | 2023-07-26 | アスチュート メディカル，インコーポレイテッド | 生体試料中において改善した性能を有する、ｔｉｍｐ２に関するアッセイ |
| AU2019272960B2 (en) | 2018-05-24 | 2024-12-12 | Renibus Therapeutics, Inc. | Methods of treating patients at risk for renal injury and renal failure |
| CN109251956A (zh) * | 2018-09-18 | 2019-01-22 | 青岛大学 | 糖尿病大鼠胰岛内MyD88 mRNA表达及黄芪的调节作用 |
| WO2020092909A1 (en) * | 2018-11-02 | 2020-05-07 | Prevencio, Inc. | Prognostic and diagnostic methods for risk of acute kidney injury |
| CN114113575B (zh) * | 2020-08-28 | 2023-06-02 | 菲鹏生物股份有限公司 | 标记复合物及其制备方法与应用 |
| CN116434960B (zh) * | 2023-06-13 | 2023-10-13 | 中国人民解放军总医院 | 一种心源性休克临床决策支持系统、设备及可存储介质 |
| WO2025033619A1 (ko) * | 2023-08-07 | 2025-02-13 | 경상국립대학교병원 | 신 대체요법 개시 결정을 위한 정보 제공 방법 및 이의 결정을 위한 말기 신질환 진단용 조성물 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| JPH05504841A (ja) | 1990-09-14 | 1993-07-22 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途 |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| FI934437L (fi) | 1991-04-10 | 1993-11-22 | Biosite Diagnostics Inc | Crosstalk-inhibitorer och deras anvaendning |
| EP0579767B1 (en) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Novel conjugates and assays for simultaneous detection of multiple ligands |
| US5324634A (en) * | 1992-03-31 | 1994-06-28 | The Research Foundation Of State University Of New York | Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| EP2083270B1 (en) | 2003-03-27 | 2019-06-12 | Children's Hospital Medical Center | A method and kit for detecting the early onset of renal tubular cell injury |
| WO2005002416A2 (en) * | 2003-06-04 | 2005-01-13 | Joslin Diabetes Center, Inc. | Predictors of renal disease |
| US20050272101A1 (en) | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| US20060003345A1 (en) * | 2004-06-30 | 2006-01-05 | Pfizer Inc | RNA bioassay |
| CN101557825A (zh) * | 2005-08-19 | 2009-10-14 | 森托科尔公司 | 抗蛋白酶解的抗体制剂 |
| WO2007144781A2 (en) * | 2006-04-21 | 2007-12-21 | Diagnotech Pty. Ltd. | Diagnostic methods and kits utilizing antibodies for metalloproteases |
| US8609812B2 (en) * | 2007-03-26 | 2013-12-17 | Novartis Ag | Use of β-2-microglobulin to assess glomerular alterations and damage in the kidney |
| US20100304413A1 (en) | 2007-11-15 | 2010-12-02 | Lars Otto Uttenthal | Diagnostic use of individual molecular forms of a biomarker |
| CA2716854A1 (en) | 2008-02-29 | 2009-09-03 | National University Corporation Nagoya University | Biomarker for the estimation of acute renal disorder and prognosis of the disorder, and use of the biomarker |
| BRPI0917711A2 (pt) * | 2008-08-28 | 2017-06-20 | Astute Medical Inc | método para avaliar o estado renal em um paciente, e, uso de um ou mais marcadores de lesão renal |
| EP2324354B1 (en) * | 2008-08-29 | 2014-07-16 | Astute Medical, Inc. | Methods for prognosis of acute renal failure |
| EP3783363A1 (en) * | 2008-10-21 | 2021-02-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| MX2011004767A (es) * | 2008-11-10 | 2011-09-06 | Astute Medical Inc | Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal. |
| US9229010B2 (en) * | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| RU2559569C2 (ru) * | 2009-06-02 | 2015-08-10 | Байокрейтс Лайф Сайенсиз Аг | Новые биомаркеры для оценки болезней почек |
| CA2770393A1 (en) * | 2009-08-07 | 2011-02-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN105004864B (zh) * | 2009-09-18 | 2017-11-03 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后方法和组合物 |
| MX2009012633A (es) * | 2009-11-23 | 2011-05-24 | Univ Mexico Nacional Autonoma | Metodo de diagnostico para detectar la lesion renal aguda a traves del uso de la proteina de choque termico de 72 kda como un biomarcador sensible. |
| EA201290387A1 (ru) * | 2009-12-20 | 2013-02-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| KR20140051754A (ko) | 2010-02-26 | 2014-05-02 | 아스튜트 메디컬 인코포레이티드 | 신장 손상 및 신부전의 진단 및 예후를 위한 방법 및 조성물 |
| WO2013043310A1 (en) * | 2011-08-26 | 2013-03-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
-
2012
- 2012-08-24 WO PCT/US2012/052298 patent/WO2013043310A1/en not_active Ceased
- 2012-08-24 AU AU2012312907A patent/AU2012312907A1/en not_active Abandoned
- 2012-08-24 TR TR2019/03235T patent/TR201903235T4/tr unknown
- 2012-08-24 CN CN201610804095.1A patent/CN106443011A/zh active Pending
- 2012-08-24 BR BR112014004389A patent/BR112014004389A2/pt not_active IP Right Cessation
- 2012-08-24 JP JP2014527328A patent/JP2014529073A/ja active Pending
- 2012-08-24 PL PL12832845T patent/PL2748605T4/pl unknown
- 2012-08-24 US US14/241,005 patent/US9459261B2/en active Active
- 2012-08-24 EP EP12832845.7A patent/EP2748605B1/en active Active
- 2012-08-24 MX MX2014002146A patent/MX346096B/es active IP Right Grant
- 2012-08-24 EA EA201490384A patent/EA201490384A1/ru unknown
- 2012-08-24 ES ES12832845T patent/ES2721907T3/es active Active
- 2012-08-24 KR KR1020147007890A patent/KR20140074307A/ko not_active Withdrawn
- 2012-08-24 PT PT12832845T patent/PT2748605T/pt unknown
- 2012-08-24 CA CA2846602A patent/CA2846602A1/en not_active Abandoned
- 2012-08-24 EP EP18209718.8A patent/EP3489690A1/en active Pending
- 2012-08-24 CN CN201280049909.5A patent/CN103874923B/zh active Active
- 2012-08-24 IN IN377MUN2014 patent/IN2014MN00377A/en unknown
-
2016
- 2016-10-03 US US15/284,197 patent/US9784750B2/en active Active
- 2016-10-19 JP JP2016204848A patent/JP2017032586A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014004389A2 (pt) | 2017-03-28 |
| EP2748605B1 (en) | 2018-12-05 |
| MX346096B (es) | 2017-03-07 |
| PT2748605T (pt) | 2019-05-03 |
| CA2846602A1 (en) | 2013-03-28 |
| IN2014MN00377A (enExample) | 2015-06-19 |
| EP3489690A1 (en) | 2019-05-29 |
| PL2748605T3 (pl) | 2019-08-30 |
| AU2012312907A1 (en) | 2014-03-13 |
| NZ706242A (en) | 2016-07-29 |
| EP2748605A1 (en) | 2014-07-02 |
| WO2013043310A1 (en) | 2013-03-28 |
| US9459261B2 (en) | 2016-10-04 |
| US9784750B2 (en) | 2017-10-10 |
| TR201903235T4 (tr) | 2019-03-21 |
| JP2014529073A (ja) | 2014-10-30 |
| US20140213477A1 (en) | 2014-07-31 |
| CN103874923A (zh) | 2014-06-18 |
| JP2017032586A (ja) | 2017-02-09 |
| EA201490384A1 (ru) | 2014-08-29 |
| NZ621716A (en) | 2016-04-29 |
| PL2748605T4 (pl) | 2019-08-30 |
| CN103874923B (zh) | 2016-09-14 |
| CN106443011A (zh) | 2017-02-22 |
| MX2014002146A (es) | 2014-08-21 |
| US20170016917A1 (en) | 2017-01-19 |
| EP2748605A4 (en) | 2015-12-02 |
| KR20140074307A (ko) | 2014-06-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2721907T3 (es) | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal | |
| NZ705411A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CL2013003605A1 (es) | Metodo para la evaluacion del riesgo de un evento tromboembólico en un sujeto que comprende determinar la presencia de serpin a 10 (inhibidor de la proteina z); kit que comprende reactivos para detectar serpin a 10. | |
| EP3734280A3 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| ES2570380T3 (es) | Método para determinar la aptitud de inhibidores de EZH2 humano en tratamiento | |
| MX2013010035A (es) | Prediccion de neoplasmas neuroendocrinos gastroenteropancreaticos (gep-nens). | |
| MX2014003153A (es) | Prediccion de riesgo de evento cardiovascular y usos del mismo. | |
| NZ598712A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| MX2017008421A (es) | Métodos terapéuticos, diagnósticos y pronósticos para el cáncer de vejiga. | |
| MX360236B (es) | Uso de marcadores en el diagnostico y tratamiento de cancer de prostata. | |
| NZ605698A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AR097542A1 (es) | Métodos y sistemas para la evaluación de la permeabilidad y la porosidad de la roca y la composición de los fluidos | |
| MX2013014153A (es) | Biomarcadores paa terapia de inhibidor de hedgehog. | |
| AR060320A1 (es) | Metodo para identificar y localizar problemas en losetas de drenaje | |
| TR201903974T4 (tr) | Tasnif makinesi için otomatik kusur tanı metodu ve cihazı. | |
| EA201500080A1 (ru) | Способ in vitro диагностирования и мониторинга рака | |
| NZ716643A (en) | Methods for predicting the risk of having a cardiovascular event and for monitoring the treatment of a cardiovascular event | |
| NZ608316A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CY1122360T1 (el) | Μεθοδος για τη διαγνωση της νοσου niemann-pick | |
| MX2021012347A (es) | Composiciones, metodos y kits para el diagnostico de una neoplasia neuroendocrina gastroenteropancreatica. | |
| NZ606124A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| MX2015009914A (es) | Dispositivos de recogida de sangre que contienen aditivos de inhibicion de la via de contacto. | |
| MX383423B (es) | Método in vitro para el diagnóstico del síndrqme del intestino irritable y la enfermedad inflamatoria intestinal. | |
| BR112018067292A2 (pt) | métodos e composições para a detecção e o diagnóstico de doença renal e doença periodontal | |
| HK1222888A1 (zh) | 预测在淋巴结阳性早期乳癌复发风险的方法 |