PT2400973T - Identificação da forma extracelular de pten que pode ser usada para tratar tumores - Google Patents

Identificação da forma extracelular de pten que pode ser usada para tratar tumores

Info

Publication number
PT2400973T
PT2400973T PT107440588T PT10744058T PT2400973T PT 2400973 T PT2400973 T PT 2400973T PT 107440588 T PT107440588 T PT 107440588T PT 10744058 T PT10744058 T PT 10744058T PT 2400973 T PT2400973 T PT 2400973T
Authority
PT
Portugal
Prior art keywords
pten
identification
treat tumors
extracellular form
extracellular
Prior art date
Application number
PT107440588T
Other languages
English (en)
Inventor
Parsons Ramon
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of PT2400973T publication Critical patent/PT2400973T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT107440588T 2009-02-17 2010-02-17 Identificação da forma extracelular de pten que pode ser usada para tratar tumores PT2400973T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20797409P 2009-02-17 2009-02-17

Publications (1)

Publication Number Publication Date
PT2400973T true PT2400973T (pt) 2017-03-07

Family

ID=42634379

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107440588T PT2400973T (pt) 2009-02-17 2010-02-17 Identificação da forma extracelular de pten que pode ser usada para tratar tumores

Country Status (18)

Country Link
US (1) US9017981B2 (pt)
EP (1) EP2400973B1 (pt)
JP (2) JP5767117B2 (pt)
CN (1) CN102387810B (pt)
AU (2) AU2010216370A1 (pt)
BR (1) BRPI1005951A2 (pt)
CA (1) CA2752590C (pt)
CY (1) CY1118861T1 (pt)
DK (1) DK2400973T3 (pt)
ES (1) ES2623393T3 (pt)
HR (1) HRP20170306T1 (pt)
HU (1) HUE032028T2 (pt)
LT (1) LT2400973T (pt)
MX (1) MX2011008695A (pt)
PL (1) PL2400973T3 (pt)
PT (1) PT2400973T (pt)
SI (1) SI2400973T1 (pt)
WO (1) WO2010096173A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6009360B2 (ja) 2010-02-17 2016-10-19 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークThe Trustees Of Columbia University In The City Of New York 分子の膜通過送達のためのptenロングリーダー配列の使用
WO2015105957A1 (en) 2014-01-08 2015-07-16 Shriners Hospitals For Children Pten antagonist peptides and methods of using the same
JP2019523008A (ja) * 2016-07-29 2019-08-22 オハイオ ステート イノベーション ファウンデーション 腫瘍溶解性ウイルスによるPTEN−Longの発現
CN109022461B (zh) * 2017-06-08 2022-01-14 中山大学附属第一医院 一种PTEN基因的上游开放阅读框45aa-uORF核苷酸序列及其编码的多肽的应用
CN108504671A (zh) * 2018-03-28 2018-09-07 宁波市医疗中心李惠利医院 一种PTEN-Long蛋白纯化制备方法
CN112236131A (zh) 2018-03-29 2021-01-15 技术研究及发展基金有限公司 包含pten抑制剂的囊泡及其用途
EP3965825A4 (en) 2019-04-12 2023-09-13 Therapten Biosciences Inc. COMPOSITIONS AND METHODS OF MAKING TUMOR SUPPRESSANT FUSIONS
CN112813046A (zh) * 2021-01-08 2021-05-18 北京大学 一种pten亚型蛋白及其应用
CN112877309B (zh) * 2021-02-19 2022-05-17 北京大学 一种N端延长型PTEN亚型PTENζ蛋白及其编码基因和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482795B1 (en) * 1997-01-30 2002-11-19 Myriad Genetics, Inc. Tumor suppressor designated TS10q23.3
EP1289472A4 (en) * 2000-05-30 2004-09-08 Advanced Res & Tech Inst COMPOSITIONS AND METHODS FOR IDENTIFYING MODULATORS OF PTEN FUNCTION AND PI-3 KINASE MECHANISMS
US20040266713A1 (en) 2003-04-23 2004-12-30 Shan Lu Methods and compositions for solid tumor treatment
WO2006034455A2 (en) * 2004-09-23 2006-03-30 Vasgene Therapeutics, Inc. Polipeptide compounds for inhibiting angiogenesis and tumor growth
JP6009360B2 (ja) 2010-02-17 2016-10-19 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークThe Trustees Of Columbia University In The City Of New York 分子の膜通過送達のためのptenロングリーダー配列の使用

Also Published As

Publication number Publication date
HRP20170306T1 (hr) 2017-04-21
ES2623393T3 (es) 2017-07-11
WO2010096173A3 (en) 2010-10-21
CN102387810A (zh) 2012-03-21
US20120039861A1 (en) 2012-02-16
EP2400973A4 (en) 2013-02-27
CN102387810B (zh) 2017-08-04
JP2015231372A (ja) 2015-12-24
JP5973035B2 (ja) 2016-08-17
CY1118861T1 (el) 2018-01-10
EP2400973A2 (en) 2012-01-04
EP2400973B1 (en) 2016-11-30
AU2016231517B2 (en) 2018-01-25
CA2752590C (en) 2017-08-22
WO2010096173A2 (en) 2010-08-26
HUE032028T2 (en) 2017-08-28
SI2400973T1 (sl) 2017-05-31
BRPI1005951A2 (pt) 2016-10-11
DK2400973T3 (en) 2017-03-06
JP2012517827A (ja) 2012-08-09
JP5767117B2 (ja) 2015-08-19
US9017981B2 (en) 2015-04-28
LT2400973T (lt) 2017-04-10
AU2010216370A1 (en) 2011-09-22
MX2011008695A (es) 2011-10-14
CA2752590A1 (en) 2010-08-26
AU2016231517A1 (en) 2016-10-06
PL2400973T3 (pl) 2017-09-29

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