PT2349300T - Terapia combinada para tratamento de doentes com distúrbios neurológicos e enfarte cerebral - Google Patents

Terapia combinada para tratamento de doentes com distúrbios neurológicos e enfarte cerebral

Info

Publication number
PT2349300T
PT2349300T PT98250798T PT09825079T PT2349300T PT 2349300 T PT2349300 T PT 2349300T PT 98250798 T PT98250798 T PT 98250798T PT 09825079 T PT09825079 T PT 09825079T PT 2349300 T PT2349300 T PT 2349300T
Authority
PT
Portugal
Prior art keywords
patients
treatment
combination therapy
neurological disorders
cerebral infarction
Prior art date
Application number
PT98250798T
Other languages
English (en)
Inventor
Lazdunski Michel
Picard David
Min Shi Xue
Original Assignee
Moleac Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moleac Pte Ltd filed Critical Moleac Pte Ltd
Publication of PT2349300T publication Critical patent/PT2349300T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Cell Biology (AREA)
  • Insects & Arthropods (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Husbandry (AREA)
  • Urology & Nephrology (AREA)
PT98250798T 2008-11-10 2009-11-10 Terapia combinada para tratamento de doentes com distúrbios neurológicos e enfarte cerebral PT2349300T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG2008083404 2008-11-10

Publications (1)

Publication Number Publication Date
PT2349300T true PT2349300T (pt) 2019-12-19

Family

ID=56378204

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98250798T PT2349300T (pt) 2008-11-10 2009-11-10 Terapia combinada para tratamento de doentes com distúrbios neurológicos e enfarte cerebral

Country Status (12)

Country Link
US (2) US8852578B2 (pt)
EP (2) EP3597201A3 (pt)
CY (1) CY1122137T1 (pt)
DK (1) DK2349300T3 (pt)
ES (1) ES2758830T3 (pt)
HR (1) HRP20192130T1 (pt)
HU (1) HUE046494T2 (pt)
LT (1) LT2349300T (pt)
PL (1) PL2349300T3 (pt)
PT (1) PT2349300T (pt)
SI (1) SI2349300T1 (pt)
WO (1) WO2010053456A1 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2411028T3 (da) 2009-03-27 2019-08-19 Moleac Pte Ltd Terapi til fremme af cellevækst
CN102462753B (zh) * 2010-11-18 2013-09-11 中国科学院上海药物研究所 治疗颈性眩晕的中药组合物及其制备方法
CN102406684B (zh) * 2011-11-29 2014-07-02 宋爱民 治疗外伤性血肿的中药制剂
CN102552708A (zh) * 2012-01-02 2012-07-11 李承平 一种平肝熄风的药物组合
ES2765878T3 (es) 2012-03-23 2020-06-11 Moleac Pte Ltd Composición neuroprotectora que comprende Poligalae, Astrágalos, Chuanxiong y Angelicae Sinensis
AU2014253521A1 (en) * 2012-03-23 2014-11-13 Moleac Pte Ltd Novel Uses for Traditional Chinese Medicine
CN102579610B (zh) * 2012-04-01 2013-09-11 李伟丽 一种治疗脑出血的中药组合物及其制备方法
CN102697904A (zh) * 2012-05-24 2012-10-03 上海交通大学医学院附属新华医院崇明分院 一种治疗急性脑梗塞的中药组合物及其制备方法和应用
CN102657839B (zh) * 2012-06-01 2013-08-28 孙庆才 一种治疗冠心病的中药胶囊
CN102688311A (zh) * 2012-06-26 2012-09-26 吉林大学珠海学院 一种具有降血压作用的中药复方制剂及其制备方法
CN103565745A (zh) 2012-08-10 2014-02-12 德克萨斯州大学系统董事会 用于治疗中风的神经保护性脂质体组合物和方法
BR112015018923B1 (pt) 2013-02-06 2022-03-03 Nc Medical Research Inc Métodos in vitro de produção de subpopulação heterogênea de células de medula óssea e para otimizar protocolo experimental para isolar população de células que trata neurodegeneração causada por acidente vascular cerebral isquêmico
CN110354067A (zh) 2013-03-15 2019-10-22 德克萨斯州大学系统董事会 富含稀有气体的液体及其制备和使用方法
CN103342729B (zh) * 2013-03-26 2016-09-14 中国科学院上海药物研究所 咖啡酰基取代的五环三萜类衍生物及其用途
CN103768307B (zh) * 2014-02-10 2017-02-01 高峰 一种治疗中风后肢体麻木的中药及其制备方法
CN104096018A (zh) * 2014-07-01 2014-10-15 栾淑丽 一种治疗面部神经麻痹症的中药组合物
CN104127797B (zh) * 2014-08-22 2017-06-06 刘兆艳 一种治疗颅脑外伤后失语的中药制剂及其制备方法
CN104398981A (zh) * 2014-11-18 2015-03-11 黄永阳 偏瘫复原汤
CN104587237A (zh) * 2014-12-19 2015-05-06 刘瑞英 一种治疗慢性脑部供血不足的中药组合物
CN105027932A (zh) * 2015-08-07 2015-11-11 融安县飞煌原生草药材专业合作社 钩藤种植方法
SG10201507607RA (en) 2015-09-14 2017-04-27 Moleac Pte Ltd Process For Producing Traditional Chinese Medicine Compositions, And Compositions Obtainable By The Process
CN108295059B (zh) * 2018-02-09 2020-07-07 广东药科大学 一种新天然产物制备促凝血或止血药物中的用途
KR102103423B1 (ko) 2018-07-09 2020-04-23 숙명여자대학교산학협력단 프루누스 세라소이데스 추출물 또는 분획물을 유효성분으로 함유하는, 뇌신경 보호용 조성물
CN108671050A (zh) * 2018-07-09 2018-10-19 刘熙安 治疗中风症的药物及其制备方法
CN110627877A (zh) * 2019-09-25 2019-12-31 成都奥达生物科技有限公司 一种psd-95抑制剂
CN113648403A (zh) * 2021-09-13 2021-11-16 四川省科学城医院 一种恢复神经正常传导机能药物及其制备方法
WO2024058722A1 (en) 2022-09-15 2024-03-21 Moleac Pte Ltd. Treating inflammation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW452494B (en) * 1996-03-12 2001-09-01 Jang De Shan Herbal composition for stimulating blood circulation
EP1335739A4 (en) * 2000-11-22 2007-07-18 Yong Chao Xia HERBAL COMPOSITION FOR THE TREATMENT OF NEURONAL INJURIES AND NEURONAL DEGENERATION, AND METHODS OF PREPARATION AND USES THEREOF
CN1259085C (zh) * 2002-09-25 2006-06-14 李雅春 加味补阳还五胶囊及其制备方法
CN1180832C (zh) * 2003-03-06 2004-12-22 张以芳 一种降压通脉的中药制剂
CN1726966B (zh) * 2005-07-27 2011-12-14 陕西步长制药有限公司 用于治疗中风和胸痹疾病的口腔崩解片制剂及其制备方法
US20070059386A1 (en) * 2005-09-12 2007-03-15 Tsun-Nin Lee Modular system for novel Chinese herbal formulas
CA2646240A1 (en) * 2006-03-16 2007-09-20 Xuemin Shi Combination therapy for treatment of patients with neurological disorders and cerebral infarction
CN101088532B (zh) * 2006-06-14 2011-06-01 山东步长制药有限公司 治疗中风和胸痹的中药制剂及其制法和质量控制方法
CN1973865A (zh) * 2006-12-25 2007-06-06 河南辅仁药业集团有限公司 一种用于治疗中风的药物组合物及其制备方法
CN101244206B (zh) * 2007-02-16 2011-07-20 刘振宏 一种治疗脑血栓的药物组合物及其制备方法
CN101194939A (zh) * 2007-12-07 2008-06-11 刘晓祥 治疗早期中风偏瘫的中药方剂

Also Published As

Publication number Publication date
EP2349300A4 (en) 2013-03-13
US20140369995A1 (en) 2014-12-18
EP3597201A3 (en) 2020-03-04
LT2349300T (lt) 2019-10-25
PL2349300T3 (pl) 2020-03-31
SI2349300T1 (sl) 2020-07-31
HRP20192130T1 (hr) 2020-02-21
CY1122137T1 (el) 2020-11-25
EP3597201A2 (en) 2020-01-22
EP2349300B1 (en) 2019-09-11
EP2349300A1 (en) 2011-08-03
HUE046494T2 (hu) 2020-03-30
US9393290B2 (en) 2016-07-19
ES2758830T3 (es) 2020-05-06
US8852578B2 (en) 2014-10-07
DK2349300T3 (da) 2019-12-02
US20110250183A1 (en) 2011-10-13
WO2010053456A1 (en) 2010-05-14

Similar Documents

Publication Publication Date Title
HRP20192130T1 (hr) Kombinacijska terapija za liječenje pacijenata s neurološkim poremećajima i moždanim udarom
IL194113A0 (en) Combination therapy for treatment of patients with neurological disorders and cerebral infarction
HK1253046A1 (zh) 用於治療神經和精神病症的雜環化合物
HK1225642A1 (zh) 用於治療假性延髓反應、神經性疾病、頑固性及慢性疼痛以及腦損傷的嗎啡喃化合物和抗抑鬱劑組合
EP2318035A4 (en) METHOD AND COMPOSITIONS FOR TREATING SYMPTOMS OF NEUROLOGICAL AND MENTAL DISORDERS
EP2278972A4 (en) TREATMENT FOR NEUROLOGICAL AND MENTAL DISORDERS
ZA200905962B (en) Combination therapy for treatment of immune disorders
EP2166837A4 (en) DRUG COMBINATION USEFUL FOR THE TREATMENT OF SKIN DISORDERS
HK1172023A1 (en) Pyrazine derivatives and their use in the treatment of neurological disorders
IL210856A0 (en) Combination therapy for the treatment of diabetes and related conditions
EP2268140A4 (en) NOVEL COMPOUNDS FOR TREATING DISEASES AND DISORDERS OF THE CENTRAL NERVOUS SYSTEM
ZA201100482B (en) Pyrazolopyrimidines and their use for the treatment of cns disorders
GB0904044D0 (en) The treatment of inflammatory disorders and pain
GB0817471D0 (en) Visual stimulation method using levels of eye contact for diagnosis and treatment of mental disorders
IL213703A (en) Compounds for the treatment of pain and other diseases
HK1152649A1 (zh) 患有輕度認知障礙需要治療的患者的鑒定方法以及這種患者的治療
EP2328584A4 (en) TREATMENT OF NEUROLOGICAL DISORDERS USING HUPERZINE
EP2212246B1 (en) TREATMENT OF NEUROLOGICAL DISORDERS
AP2779A (en) Treatment of CNS and pain disorders
HK1145282A1 (en) Treatment of sleep disorders
GB0814043D0 (en) The treatment of skin disorders
GB0803397D0 (en) The treatment of inflammatory disorders and pain
GB0817330D0 (en) The treatment of inflammatory disorders and pain
IL190528A0 (en) Synergistic drug combinations for the treatment of ocular surface disorders