HK1225642A1 - 用於治療假性延髓反應、神經性疾病、頑固性及慢性疼痛以及腦損傷的嗎啡喃化合物和抗抑鬱劑組合 - Google Patents

用於治療假性延髓反應、神經性疾病、頑固性及慢性疼痛以及腦損傷的嗎啡喃化合物和抗抑鬱劑組合

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Publication number
HK1225642A1
HK1225642A1 HK16114072A HK16114072A HK1225642A1 HK 1225642 A1 HK1225642 A1 HK 1225642A1 HK 16114072 A HK16114072 A HK 16114072A HK 16114072 A HK16114072 A HK 16114072A HK 1225642 A1 HK1225642 A1 HK 1225642A1
Authority
HK
Hong Kong
Prior art keywords
intractable
antidepressant
treatment
combination
brain injury
Prior art date
Application number
HK16114072A
Other languages
English (en)
Inventor
Amanda Thomas
Original Assignee
Concert Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Concert Pharmaceuticals Inc filed Critical Concert Pharmaceuticals Inc
Publication of HK1225642A1 publication Critical patent/HK1225642A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16114072A 2008-10-30 2016-12-09 用於治療假性延髓反應、神經性疾病、頑固性及慢性疼痛以及腦損傷的嗎啡喃化合物和抗抑鬱劑組合 HK1225642A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10983208P 2008-10-30 2008-10-30

Publications (1)

Publication Number Publication Date
HK1225642A1 true HK1225642A1 (zh) 2017-09-15

Family

ID=41346111

Family Applications (2)

Application Number Title Priority Date Filing Date
HK12106050.0A HK1165294A1 (zh) 2008-10-30 2012-06-20 用於治療假性延髓情緒及含嗎啡喃類化合物及抗抑鬱劑的組合
HK16114072A HK1225642A1 (zh) 2008-10-30 2016-12-09 用於治療假性延髓反應、神經性疾病、頑固性及慢性疼痛以及腦損傷的嗎啡喃化合物和抗抑鬱劑組合

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK12106050.0A HK1165294A1 (zh) 2008-10-30 2012-06-20 用於治療假性延髓情緒及含嗎啡喃類化合物及抗抑鬱劑的組合

Country Status (11)

Country Link
US (5) US20120083487A1 (zh)
EP (4) EP3090760A1 (zh)
CY (1) CY1117760T1 (zh)
DK (1) DK2397158T3 (zh)
HK (2) HK1165294A1 (zh)
HR (1) HRP20160454T1 (zh)
HU (1) HUE028956T2 (zh)
PL (1) PL2397158T3 (zh)
PT (1) PT2397158T (zh)
SI (1) SI2397158T1 (zh)
WO (1) WO2010062692A1 (zh)

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CY1117760T1 (el) 2017-05-17
WO2010062692A1 (en) 2010-06-03
US20160143902A1 (en) 2016-05-26
EP2397158A2 (en) 2011-12-21
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EP2397158B1 (en) 2016-04-13
US20120083487A1 (en) 2012-04-05
SI2397158T1 (sl) 2016-07-29
HUE028956T2 (en) 2017-01-30
EP2365808B1 (en) 2018-01-10
DK2397158T3 (en) 2016-07-25
EP2365808A1 (en) 2011-09-21
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EP2397158A3 (en) 2012-02-22
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