PT2343079E - Técnica e dispositivo de preparação de células em suspensão - Google Patents

Técnica e dispositivo de preparação de células em suspensão Download PDF

Info

Publication number
PT2343079E
PT2343079E PT101842359T PT10184235T PT2343079E PT 2343079 E PT2343079 E PT 2343079E PT 101842359 T PT101842359 T PT 101842359T PT 10184235 T PT10184235 T PT 10184235T PT 2343079 E PT2343079 E PT 2343079E
Authority
PT
Portugal
Prior art keywords
cell suspension
preparation device
suspension preparation
cell
suspension
Prior art date
Application number
PT101842359T
Other languages
English (en)
Inventor
Marie Stoner
Fiona Wood
Original Assignee
Avita Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avita Medical Ltd filed Critical Avita Medical Ltd
Publication of PT2343079E publication Critical patent/PT2343079E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/10Hair or skin implants
    • A61F2/105Skin implants, e.g. artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/02Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/06Means for pre-treatment of biological substances by chemical means or hydrolysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/09Means for pre-treatment of biological substances by enzymatic treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/22Means for packing or storing viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629Keratinocytes; Whole skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/09Body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters
    • A61M2205/7545General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/98Xeno-free medium and culture conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/99Serum-free medium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
PT101842359T 2001-02-07 2002-02-07 Técnica e dispositivo de preparação de células em suspensão PT2343079E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR2989A AUPR298901A0 (en) 2001-02-07 2001-02-07 Cell suspension preparation technique and device
US28152701P 2001-04-04 2001-04-04

Publications (1)

Publication Number Publication Date
PT2343079E true PT2343079E (pt) 2015-07-16

Family

ID=3827012

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101842359T PT2343079E (pt) 2001-02-07 2002-02-07 Técnica e dispositivo de preparação de células em suspensão

Country Status (5)

Country Link
US (9) US20020106353A1 (pt)
EP (2) EP2957288B1 (pt)
AU (1) AUPR298901A0 (pt)
ES (2) ES2747300T3 (pt)
PT (1) PT2343079E (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR298901A0 (en) * 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
NZ597965A (en) 2003-10-08 2013-09-27 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
WO2007047707A1 (en) * 2005-10-17 2007-04-26 Aderans Research Institute, Inc. Method of delivering hair follicle progenitor cells to the skin
DE102007040252A1 (de) * 2006-09-11 2008-06-12 Gerlach, Jörg, Prof. Dr. Sprühapparat für Zellen und Methode zur Anwendung gesprühter Zellen
EP2089076A2 (en) * 2006-10-13 2009-08-19 Reliance Life Sciences Pvt., Ltd. Cultured melanocytes on biopolymers
WO2009100219A1 (en) * 2008-02-05 2009-08-13 University Of Virginia Patent Foundation Spraying device and related method for cell aggregates and cell aggregate suspension thereof
EP3443991A1 (en) 2010-05-25 2019-02-20 Cook Biotech Incorporated Methods, substrates, and systems useful for cell seeding of medical grafts
US9149952B2 (en) * 2010-10-21 2015-10-06 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
DE102011100450B8 (de) 2011-04-27 2013-10-17 Jörg Gerlach Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat
US20150079153A1 (en) * 2012-03-22 2015-03-19 Avita Medical Ltd. Cell Suspension and Use Thereof
FR2991690B1 (fr) * 2012-06-07 2020-02-28 Laboratoires Genevrier Utilisation d'une chaufferette pour favoriser une reaction biologique
JP6195617B2 (ja) 2012-07-05 2017-09-13 ピー.シー.オー.エー. デバイシズ エルティーディー.P.C.O.A. Devices Ltd. 薬剤ディスペンサ
JP6392223B2 (ja) 2012-07-30 2018-09-19 ピー.シー.オー.エー. デバイシズ エルティーディー.P.C.O.A. Devices Ltd. ピルを収容し投薬するためのレセプタクル
AU2013205148B2 (en) 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
CN103810779A (zh) * 2014-02-13 2014-05-21 郭任 蓝牙低功耗锁芯
WO2015145269A2 (en) * 2014-03-20 2015-10-01 Casey Patrick J Method for the treatment of damaged tissue
IL233295B (en) 2014-06-22 2019-11-28 Ilan Paz A control pill dispensing system
US20160177250A1 (en) * 2014-06-25 2016-06-23 Cytori Therapeutics, Inc. Tissue transfer system
CN104232475B (zh) * 2014-09-17 2017-01-11 中国人民解放军第二军医大学 一种快速即时分离人皮肤表皮细胞、黑色素细胞和成纤维细胞的装置及方法
IL238387B (en) 2015-04-20 2019-01-31 Paz Ilan Drug dispenser release mechanism
EP3362030B1 (en) 2015-10-15 2023-09-06 Dosentrx Ltd. Image recognition-based dosage form dispensers
US11458072B2 (en) 2015-11-02 2022-10-04 Dosentrx Ltd. Lockable advanceable oral dosage form dispenser containers
US20200261618A1 (en) * 2016-01-06 2020-08-20 The Research Foundation For The State University Of New York Liquid tissue graft
EP3257464B1 (en) * 2016-06-14 2020-09-30 RenovaCare Sciences Corp. Disposable apparatus and device with unsterile reusable apparatus for sterile application of a liquid
EP4008440A1 (en) 2016-06-14 2022-06-08 RenovaCare Sciences Corp. Modular device for cell spraying
EP3541923A4 (en) * 2016-11-15 2020-06-17 Regrow Biosciences Pvt. Ltd. METHOD FOR PRODUCING A BUCCAL EPITHELIC CELL SUSPENSION AND THE USE THEREOF
CN108795759B (zh) * 2018-07-03 2021-08-06 大连理工大学 用于剪应力与趋化因子定量调控细胞划痕修复实验的微流控系统及方法
US20220323644A1 (en) * 2019-09-09 2022-10-13 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method of treating or repairing an abdominal wall opening
US11987787B2 (en) * 2020-07-22 2024-05-21 AVITA Medical Americas, LLC Devices, methods, and kits for preparing a cell suspension
CN112961820A (zh) * 2021-02-04 2021-06-15 王忠坤 一种皮肤组织采集、提取并制备细胞悬液的方法和装置
US20240209296A1 (en) 2022-12-27 2024-06-27 AVITA Medical Americas, LLC Tissue healing

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1356794A (en) * 1919-12-27 1920-10-26 Smith John Thomas Skid-oiler
US3647632A (en) * 1968-04-11 1972-03-07 Little Inc A Apparatus for cell culture
US3608553A (en) * 1969-09-04 1971-09-28 Ultrasonic Systems Ultrasonic method and apparatus for tissue grafting
JPS497414A (pt) * 1972-05-24 1974-01-23
US4059486A (en) * 1976-11-03 1977-11-22 Monsanto Company Cell culture process
US4377010A (en) * 1978-11-08 1983-03-22 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Biocompatible material comprising a base polymer bulk graft polymerized with an ethylenically unsaturated carboxylic acid
FR2461002A1 (fr) * 1979-07-13 1981-01-30 Inst Nat Sante Rech Med Procede pour stimuler la croissance des cellules d'epiderme humain et produits faisant application dudit procede
US4254226A (en) * 1979-09-13 1981-03-03 Sloan Kettering Institute For Cancer Research Process for growing human epidermal cells in tissue culture
US4304866A (en) * 1979-11-14 1981-12-08 Massachusetts Institute Of Technology Transplantable sheets of living keratinous tissue
US4350768A (en) * 1980-09-19 1982-09-21 Bristol Myers Company Method for preparing single cell suspension
US4510144A (en) * 1981-08-26 1985-04-09 Newport Pharmaceuticals International Methods of imparting immunomodulating activity with dihydrothiazolo purine derivatives
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
US4458678A (en) 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US5328695A (en) * 1983-03-22 1994-07-12 Massachusetts Institute Of Technology Muscle morphogenic protein and use thereof
US4649115A (en) * 1983-03-31 1987-03-10 Sloan-Kettering Institute Monoclonal antibodies to skin cells
US4769317A (en) * 1983-06-14 1988-09-06 Hefton John M Process for growing human epidermis, product thereof
US5000963A (en) * 1983-06-14 1991-03-19 Hefton John M Method of treating the skin using human epidermal sheets
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US5441539A (en) * 1985-06-06 1995-08-15 Thomas Jefferson University Endothelial cell deposition device
US5460939A (en) * 1986-04-18 1995-10-24 Advanced Tissue Sciences, Inc. Temporary living skin replacement
US5079160A (en) * 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
US5015584A (en) * 1987-10-14 1991-05-14 Board Of Regents, The University Of Texas System Epidermal graft system
GB8816516D0 (en) * 1988-07-12 1988-08-17 Welsh Water Authority Portable incubator and incubating kit
JPH0372872A (ja) 1988-07-12 1991-03-28 Bio Kagaku Kenkyusho:Kk 無血清培地及びそれを用いた哺乳類細胞の培養法
US5139031A (en) * 1989-09-18 1992-08-18 La Mina Ltd. Method and device for cytology and microbiological testing
US5292655A (en) * 1990-01-29 1994-03-08 Wille Jr John J Method for the formation of a histologically-complete skin substitute
EP0444270A1 (en) * 1990-02-26 1991-09-04 Thomas Jefferson University Endothelial cell deposition device
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets
JPH07504398A (ja) * 1991-03-26 1995-05-18 オレゴン州 真皮に対する表皮ケラチン細胞の接着を改善する生成物および方法
US5556783A (en) * 1991-03-27 1996-09-17 Trustees Of Univ. Of Penna Methods of culturing and modulating the growth of hair follicular stem cells
ATE307599T1 (de) * 1991-11-20 2005-11-15 Innogenetics Nv Keratinozyt-abstammende granulate zur verwendung als wundheilendes mittel
AU672006B2 (en) * 1992-04-17 1996-09-19 Abbott Laboratories Taxol derivatives
US5955343A (en) * 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
CA2158159A1 (en) * 1993-05-05 1994-11-10 David F. Negrotti Modular laboratory equipment and coupling system
US5571083A (en) * 1994-02-18 1996-11-05 Lemelson; Jerome H. Method and system for cell transplantation
US5507385A (en) * 1994-08-12 1996-04-16 Rubbermaid Incorporated Multipurpose storage bin
US5518612A (en) * 1994-08-30 1996-05-21 Becton, Dickinson And Company Cell strainer assembly and method of use
US5650317A (en) * 1994-09-16 1997-07-22 Michigan State University Human breast epithelial cell type with stem cell and luminal epithelial cell characteristics
US5851522A (en) 1995-06-07 1998-12-22 Trustees Of Tufts College Enhancing keratinocyte migration
US6238908B1 (en) * 1995-06-07 2001-05-29 Aastrom Biosciences, Inc. Apparatus and method for maintaining and growth biological cells
DK0780469T3 (da) * 1995-12-21 2001-03-26 Nestle Sa Udødeliggjorte cellelinier stammende fra normalt menneskeligt hudvæv og serumfrit vækstmedium til dyrkning af sådanne
WO1997045449A1 (en) * 1996-05-29 1997-12-04 Derek Nigel John Hart Dendritic cell receptor
DE29609565U1 (de) * 1996-05-29 1996-08-22 Udo Heisig GmbH, 85609 Aschheim Folienschlauchabdeckung für medizinische Geräte
AU3990197A (en) * 1996-10-04 1998-04-09 Metropolitan Health Service Board Method of engraftment of cultured cells
AUPO275296A0 (en) 1996-10-04 1996-10-31 Institute for Research into Tissue Repair, Regeneration and Reconstruction Method for engraftment of cultured cells
IL120909A0 (en) 1997-05-26 1997-09-30 Lrr & D Ltd Compositions and means for the treatment of burns and other cutaneous traumas
US5786207A (en) * 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
IT1293484B1 (it) 1997-06-11 1999-03-01 Fidia Advanced Biopolymers Srl Materiale biologico comprendente una efficiente coltura di cellule e una matrice tridimensionale biocompatibile e biodegradabile
DK1011699T3 (da) 1997-09-11 2002-03-11 Purdue Research Foundation Galactosidase-modificeret submucosavæv
AU1664299A (en) 1997-10-25 1999-05-17 Roche Diagnostics Gmbh Autodegradable microcarriers and their use
US20010048917A1 (en) 1998-03-09 2001-12-06 Warren Hoeffler Skin equivalent and methods of forming and using same
US6080581A (en) * 1998-07-02 2000-06-27 Charles Daniel Anderson Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same
US6207451B1 (en) * 1998-09-15 2001-03-27 The Regents Of The University Of Michigan Mammalian muscle construct and method for producing same
DE69906668D1 (de) * 1998-11-30 2003-05-15 Isotis Bv Kunsthaut
NZ528340A (en) * 1998-12-02 2005-07-29 Bristol Myers Squibb Co Spray delivery of cells
JP2002537851A (ja) 1999-03-09 2002-11-12 アコルディス インダストリアル ファイバース ゲゼルシャフト ミット ベシュレンクテル ハフツング 作用物質のインビトロテスト法、その装置および使用
US6391541B1 (en) 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
DE19958693C2 (de) * 1999-12-06 2002-07-18 Biotissue Technologies Gmbh Verfahren und Zusammensetzungen zur Herstellung von Zelltransplantaten
US7081240B1 (en) 2000-06-28 2006-07-25 Zimmer Orthobiologics, Inc. Protein mixtures for wound healing
AU2002224519A1 (en) * 2000-07-21 2002-02-05 Atropos Limited A surgical instrument
US6673603B2 (en) 2000-09-01 2004-01-06 Modex Therapeutiques, S.A. Cell paste comprising keratinocytes and fibroblasts
US7628780B2 (en) * 2001-01-13 2009-12-08 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
ATE510548T1 (de) 2001-02-07 2011-06-15 Mccomb Foundation Inc Zellsuspensionsherstellungstechnik und verwendung
WO2002066598A1 (de) 2001-02-20 2002-08-29 Max-Delbrück-Centrum für Molekulare Medizin System zur automatischen isolierung von lebenden zellen aus tierischen geweben
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
FI20020197A0 (fi) 2002-02-01 2002-02-01 Orion Corp Yhdistelmä akuutin myokardiilisen infarktin hoitoon
US9144583B2 (en) 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
US20050026275A1 (en) 2003-06-23 2005-02-03 Andrej Bahoric Device, system and method for receiving, processing and dispersing cells
BRPI0414455A (pt) 2003-09-17 2006-11-14 Macropore Biosurgery Inc métodos para usar células regenerativas no tratamento de doença vascular periférica e distúrbios afins
JP2007530543A (ja) 2004-03-22 2007-11-01 オシリス セラピューティクス,インコーポレイテッド 間葉幹細胞及びその使用法
US7655465B2 (en) 2004-06-07 2010-02-02 Massachusetts Institute Of Technology Methods for ex vivo propagation of somatic hair follicle stem cells
EP2980206A1 (en) 2004-07-01 2016-02-03 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
JP4731556B2 (ja) 2004-07-02 2011-07-27 サイトリ セラピューティクス インコーポレイテッド 臨床的に安全な脂肪組織由来再生細胞を単離し、使用するためのシステムおよび方法
US8568761B2 (en) 2005-07-15 2013-10-29 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent myocardium
US8216528B2 (en) 2005-09-29 2012-07-10 Sysmex Corporation Sample preparation kit, sample preparation container, and sample processing device
CA2641170C (en) 2006-02-07 2016-04-12 Spinalcyte, Llc Methods and compositions for repair of cartilage using an in vivo bioreactor
US9259445B2 (en) 2006-06-07 2016-02-16 Universidad Tecnica Federico Santa Maria Integrated implant system (IIS) biocompatible, biodegradable and bioactive, comprising a biocompatible sterile porous polymeric matrix and a gel, integrating in situ the tridimensional matrix structure
US20070286880A1 (en) 2006-06-08 2007-12-13 Andrey Vasiliev Inoculated spongiform scaffold for transplantation and tissue regeneration
WO2008086358A1 (en) 2007-01-08 2008-07-17 University Of Southern California Usc Stevens Skin wound healing compositions and methods of use thereof
WO2009073724A1 (en) 2007-12-04 2009-06-11 Ingeneron, Inc. Apparatus and methods for cell isolation
CA2723760A1 (en) 2008-05-07 2009-11-12 Ucl Business Plc Biomimetic cell scaffolds
WO2010033740A2 (en) 2008-09-17 2010-03-25 Pressure Biosciences Inc. Shredder for mechanical disruption by gentle controlled compressive rotation
US9057064B1 (en) 2009-02-25 2015-06-16 Ag-Defense Systems, Inc. Method and apparatus for extracting DNA from a biological sample
KR101738324B1 (ko) 2009-05-01 2017-05-19 비미니 테크놀로지스 엘엘씨 조직 및 세포 부유화 이식편의 최적화 시스템, 방법 및 조성물
US8207118B2 (en) 2009-07-17 2012-06-26 University Of Southern California Skin wound healing compositions and methods of use thereof
US8921103B2 (en) 2009-08-28 2014-12-30 Board Of Regents, The University Of Texas System Laminar construct for tissue-engineered dermal equivalent
FR2950074B1 (fr) 2009-09-16 2017-10-06 Oreal Equivalent de peau in vitro et procede de preparation
CN102781463A (zh) 2009-10-07 2012-11-14 戈诺珍公司 用于皮肤再生的方法和组合物
CN101914495A (zh) 2010-07-22 2010-12-15 吉林大学 用于体外大量扩增毛囊干细胞的培养方法
US8162247B2 (en) 2010-08-17 2012-04-24 Biomedical Polymers, Inc. Grinding system
US9150826B2 (en) 2011-03-14 2015-10-06 Zymo Research Corporation Portable sample disruptor apparatus, kits, and methods
SI2502986T1 (sl) 2011-03-22 2019-11-29 Cartiregen B V Sistem za obdelavo hrustančnih celic
US10934519B2 (en) 2011-07-29 2021-03-02 Global Life Sciences Solutions Usa Llc Systems, methods and control laws for cell harvesting
US20150004702A1 (en) 2011-08-29 2015-01-01 Stempeutics Research Private Limited System for isolating stromal vascular fraction (svf) cells from the adipose tissue and a method thereof
SG11201402149TA (en) 2011-11-08 2014-06-27 Auxocell Lab Inc Systems and methods for processing cells
DE102012002795A1 (de) 2012-02-15 2013-08-22 Claas Selbstfahrende Erntemaschinen Gmbh Schutzvorrichtung für ein Schneidwerk eines selbstfahrenden Mähdreschers
US20150079153A1 (en) 2012-03-22 2015-03-19 Avita Medical Ltd. Cell Suspension and Use Thereof
FR2991690B1 (fr) 2012-06-07 2020-02-28 Laboratoires Genevrier Utilisation d'une chaufferette pour favoriser une reaction biologique
AU2013205148B2 (en) 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
US10436680B2 (en) 2013-10-15 2019-10-08 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method

Also Published As

Publication number Publication date
EP2957288A1 (en) 2015-12-23
ES2534353T3 (es) 2015-04-21
US10729536B2 (en) 2020-08-04
US20110150848A1 (en) 2011-06-23
US20180098840A1 (en) 2018-04-12
US20150182739A1 (en) 2015-07-02
EP2957288B1 (en) 2019-08-07
US20020106353A1 (en) 2002-08-08
US9078741B2 (en) 2015-07-14
US20070042488A1 (en) 2007-02-22
EP3632452A1 (en) 2020-04-08
ES2747300T3 (es) 2020-03-10
US9029140B2 (en) 2015-05-12
US10631974B2 (en) 2020-04-28
US20210169636A1 (en) 2021-06-10
US20110311497A1 (en) 2011-12-22
US20100196334A1 (en) 2010-08-05
US9867692B2 (en) 2018-01-16
US20190307550A1 (en) 2019-10-10
AUPR298901A0 (en) 2001-03-08

Similar Documents

Publication Publication Date Title
PT2343079E (pt) Técnica e dispositivo de preparação de células em suspensão
GB2377079B (en) Battery
EP1416550A4 (en) BATTERY
HK1073689A1 (en) Micro-sensor
HK1064934A1 (en) Beta-amyloid-analogue-t-cell epitop vaccine
HUP0102502A3 (en) Suspension device
AU2002366160A8 (en) Zinc-alkaline battery containing lambda-mn02
TW580228U (en) Carrying structure
EP1420469A4 (en) CELL
GB0116057D0 (en) Nano-electrochemical cells
EP1406322A4 (en) BATTERY
AU2001279774A1 (en) Suspension device
GB2375570B (en) Suspension device
TW595555U (en) Suspension
GB2381945B (en) Cell
GB0118691D0 (en) Easy weigh
GB9920764D0 (en) Suspension device
HK1052434A1 (zh) 懸掛裝置
AU2001290476A1 (en) Suspension device
TW493677U (en) Doorstopper structure
AU147945S (en) Cell suspension preparation kit
TW574995U (en) Structure for mini-bicycle
TW530864U (en) Improved axle structure
GB0021228D0 (en) Suspension device
IL143807A0 (en) Cell interface