PT2183379E - Enriquecimento de uma sequência alvo - Google Patents
Enriquecimento de uma sequência alvo Download PDFInfo
- Publication number
- PT2183379E PT2183379E PT87949160T PT08794916T PT2183379E PT 2183379 E PT2183379 E PT 2183379E PT 87949160 T PT87949160 T PT 87949160T PT 08794916 T PT08794916 T PT 08794916T PT 2183379 E PT2183379 E PT 2183379E
- Authority
- PT
- Portugal
- Prior art keywords
- enrichment
- target sequence
- sequence
- target
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96283807P | 2007-08-01 | 2007-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2183379E true PT2183379E (pt) | 2015-09-25 |
Family
ID=40305136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87949160T PT2183379E (pt) | 2007-08-01 | 2008-07-31 | Enriquecimento de uma sequência alvo |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8455190B2 (https=) |
| EP (1) | EP2183379B1 (https=) |
| JP (1) | JP5531367B2 (https=) |
| KR (1) | KR101376359B1 (https=) |
| CN (1) | CN101815789B (https=) |
| AU (1) | AU2008282780B2 (https=) |
| CA (1) | CA2695264C (https=) |
| DK (1) | DK2183379T3 (https=) |
| ES (1) | ES2547053T3 (https=) |
| PT (1) | PT2183379E (https=) |
| WO (1) | WO2009017784A2 (https=) |
Families Citing this family (75)
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| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8980561B1 (en) | 2006-08-22 | 2015-03-17 | Los Alamos National Security, Llc. | Nucleic acid detection system and method for detecting influenza |
| US20090047673A1 (en) | 2006-08-22 | 2009-02-19 | Cary Robert B | Miniaturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids |
| ES2582602T3 (es) | 2007-03-28 | 2016-09-14 | Signal Diagnostics | Sistema y método de análisis de alta resolución de ácidos nucleicos para detectar variaciones de secuencia |
| JP5531367B2 (ja) | 2007-08-01 | 2014-06-25 | ダナ−ファーバー キャンサー インスチテュート | 標的配列の濃縮 |
| EP2279403B1 (en) | 2008-05-05 | 2016-03-16 | Los Alamos National Security, LLC | Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control |
| US10669574B2 (en) | 2008-11-18 | 2020-06-02 | XCR Diagnostics, Inc. | DNA amplification technology |
| AU2011224534B2 (en) * | 2010-03-08 | 2014-10-09 | Dana-Farber Cancer Institute, Inc. | Full COLD-PCR enrichment with reference blocking sequence |
| KR101312241B1 (ko) * | 2010-04-27 | 2013-09-27 | 사회복지법인 삼성생명공익재단 | 증폭억제시발체를 이용하는 유전자 돌연변이 검출 방법 |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| WO2011146632A1 (en) | 2010-05-18 | 2011-11-24 | Gene Security Network Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12545960B2 (en) | 2010-05-18 | 2026-02-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| CN103608466B (zh) | 2010-12-22 | 2020-09-18 | 纳特拉公司 | 非侵入性产前亲子鉴定方法 |
| RU2671980C2 (ru) | 2011-02-09 | 2018-11-08 | Натера, Инк. | Способы неинвазивного пренатального установления плоидности |
| JP2014507950A (ja) * | 2011-02-28 | 2014-04-03 | トランスゲノミック，インク． | 混合個体群における標的ｄｎａを配列決定するためのキットおよび方法 |
| ITTO20110271A1 (it) | 2011-03-28 | 2012-09-29 | Fabio Gentilini | Metodo per l'identificazione di polimorfismi genetici di base singola. |
| EP2691541B1 (en) * | 2011-03-31 | 2017-10-18 | Dana-Farber Cancer Institute, Inc. | Method for enriching in single-stranded mutant sequences from mixture of wild-type and mutant sequences |
| CN103608467B (zh) | 2011-04-20 | 2017-07-21 | 美飒生物技术公司 | 用于核酸的振荡扩增反应 |
| US9796748B2 (en) | 2011-05-02 | 2017-10-24 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
| US9617392B2 (en) | 2011-07-10 | 2017-04-11 | President And Fellows Of Harvard College | Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units |
| WO2013010074A1 (en) | 2011-07-13 | 2013-01-17 | Primeradx, Inc. | Multimodal methods for simultaneous detection and quantification of multiple nucleic acids in a sample |
| US9074247B2 (en) * | 2011-10-06 | 2015-07-07 | Drexel University | P53 assay for a urine test for HCC screening |
| CN103998921B (zh) | 2011-10-14 | 2016-04-20 | 贝克顿·迪金森公司 | 方波热循环 |
| US9133490B2 (en) | 2012-05-16 | 2015-09-15 | Transgenomic, Inc. | Step-up method for COLD-PCR enrichment |
| US20150126376A1 (en) * | 2012-06-14 | 2015-05-07 | Fred Hutchinson Cancer Research Center | Compositions and methods for sensitive mutation detection in nucleic acid molecules |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| US9732390B2 (en) | 2012-09-20 | 2017-08-15 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of fetus or tumor from plasma |
| US10706957B2 (en) | 2012-09-20 | 2020-07-07 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of tumor from plasma |
| US10913977B2 (en) * | 2013-07-24 | 2021-02-09 | Dana-Farber Cancer Institute, Inc. | Methods and compositions to enable enrichment of minor DNA alleles by limiting denaturation time in PCR or simply enable enrichment of minor DNA alleles by limiting the denaturation time in PCR |
| KR102323375B1 (ko) | 2013-10-09 | 2021-11-08 | 플루어레센트릭 인코포레이티드 | 다중 프로브 |
| CA2922261A1 (en) * | 2013-10-20 | 2015-05-21 | Trovagene, Inc. | Synthesis and enrichment of nucleic acid sequences |
| CN105283555A (zh) * | 2013-10-20 | 2016-01-27 | 特罗瓦基因公司 | 核酸序列的合成和富集 |
| CN103602748A (zh) * | 2013-11-28 | 2014-02-26 | 瑞希基因科技（北京）股份有限公司 | 一种结合荧光定量pcr技术的焦磷酸测序方法 |
| CA2945962C (en) | 2014-04-21 | 2023-08-29 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| CN106687589B (zh) * | 2014-07-10 | 2021-05-07 | 弗洛雷森特里克公司 | Dna扩增技术 |
| TWI813141B (zh) | 2014-07-18 | 2023-08-21 | 香港中文大學 | Ｄｎａ混合物中之組織甲基化模式分析 |
| EP3286546B1 (en) | 2015-04-24 | 2023-07-19 | Mesa Biotech, Inc. | Fluidic test cassette |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| PL3298162T3 (pl) | 2015-05-18 | 2020-07-27 | Saga Diagnostics Ab | Wykrywanie docelowego kwasu nukleinowego i wariantów |
| US10689710B2 (en) * | 2015-05-27 | 2020-06-23 | Quest Diagnostics Investments Incorporated | Methods for screening solid tumors for mutations |
| WO2017070339A1 (en) * | 2015-10-20 | 2017-04-27 | Richardson Katherine | Microfluidic device for enrichment of nucleic acid sequence alterations |
| RU2760913C2 (ru) | 2016-04-15 | 2021-12-01 | Натера, Инк. | Способы выявления рака легкого |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| KR20260032575A (ko) | 2016-11-30 | 2026-03-09 | 더 차이니즈 유니버시티 오브 홍콩 | 소변 및 기타 샘플에서의 무세포 dna의 분석 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| WO2018111835A1 (en) | 2016-12-12 | 2018-06-21 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection |
| US11174511B2 (en) | 2017-07-24 | 2021-11-16 | Dana-Farber Cancer Institute, Inc. | Methods and compositions for selecting and amplifying DNA targets in a single reaction mixture |
| WO2019099420A1 (en) * | 2017-11-15 | 2019-05-23 | Yan Wang | A method for detecting multiple dna mutations and copy number variations |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| DE202019005627U1 (de) | 2018-04-02 | 2021-05-31 | Grail, Inc. | Methylierungsmarker und gezielte Methylierungssondenpanels |
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| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| JP6544783B1 (ja) | 2018-07-31 | 2019-07-17 | 学校法人 岩手医科大学 | がんの診断のためのプローブ／プライマーライブラリー |
| WO2020069350A1 (en) | 2018-09-27 | 2020-04-02 | Grail, Inc. | Methylation markers and targeted methylation probe panel |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| WO2021034999A1 (en) | 2019-08-21 | 2021-02-25 | Dana-Farber Cancer Institute, Inc. | Multi-site enrichment of deletions in dna microsatellites |
| US11866793B2 (en) | 2020-03-27 | 2024-01-09 | Regents Of The University Of Minnesota | Assay for detecting palmer amaranth DNA in individual and mixed samples |
| EP4624573A1 (en) | 2022-11-22 | 2025-10-01 | Quantdetect, Inc. | Probe/primer library for cancer diagnosis |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5310652A (en) | 1986-08-22 | 1994-05-10 | Hoffman-La Roche Inc. | Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| GB2228086A (en) | 1988-11-25 | 1990-08-15 | Ici Plc | Characterisation of genomic DNA |
| KR920700360A (ko) | 1989-03-22 | 1992-02-19 | 하리크 프리드리히 | 미끄럼 베어링 |
| US5075217A (en) | 1989-04-21 | 1991-12-24 | Marshfield Clinic | Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences |
| AU5645690A (en) | 1989-05-05 | 1990-11-29 | Lifecodes Corporation | Method for genetic analysis of a nucleic acid sample |
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| US5849497A (en) | 1997-04-03 | 1998-12-15 | The Research Foundation Of State University Of New York | Specific inhibition of the polymerase chain reaction using a non-extendable oligonucleotide blocker |
| JP3785517B2 (ja) | 1997-06-05 | 2006-06-14 | 東ソー株式会社 | 核酸融解温度測定法 |
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-
2008
- 2008-07-31 JP JP2010519925A patent/JP5531367B2/ja not_active Expired - Fee Related
- 2008-07-31 AU AU2008282780A patent/AU2008282780B2/en not_active Ceased
- 2008-07-31 PT PT87949160T patent/PT2183379E/pt unknown
- 2008-07-31 CN CN2008801098230A patent/CN101815789B/zh active Active
- 2008-07-31 EP EP08794916.0A patent/EP2183379B1/en not_active Not-in-force
- 2008-07-31 ES ES08794916.0T patent/ES2547053T3/es active Active
- 2008-07-31 US US12/671,295 patent/US8455190B2/en not_active Expired - Fee Related
- 2008-07-31 WO PCT/US2008/009248 patent/WO2009017784A2/en not_active Ceased
- 2008-07-31 KR KR1020107004305A patent/KR101376359B1/ko not_active Expired - Fee Related
- 2008-07-31 DK DK08794916.0T patent/DK2183379T3/en active
- 2008-07-31 CA CA2695264A patent/CA2695264C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2695264A1 (en) | 2009-02-05 |
| WO2009017784A3 (en) | 2009-03-26 |
| US8455190B2 (en) | 2013-06-04 |
| EP2183379A4 (en) | 2011-08-10 |
| EP2183379A2 (en) | 2010-05-12 |
| AU2008282780A1 (en) | 2009-02-05 |
| KR20100044870A (ko) | 2010-04-30 |
| KR101376359B1 (ko) | 2014-03-27 |
| US20100203532A1 (en) | 2010-08-12 |
| JP2010535031A (ja) | 2010-11-18 |
| ES2547053T3 (es) | 2015-10-01 |
| EP2183379B1 (en) | 2015-04-15 |
| DK2183379T3 (en) | 2015-07-27 |
| WO2009017784A2 (en) | 2009-02-05 |
| CN101815789A (zh) | 2010-08-25 |
| CN101815789B (zh) | 2013-06-12 |
| AU2008282780B2 (en) | 2014-04-17 |
| JP5531367B2 (ja) | 2014-06-25 |
| CA2695264C (en) | 2015-01-27 |
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| PL2112455T3 (pl) | Urządzenie rozruchowe | |
| GB0609979D0 (en) | Target | |
| GB2470421B (en) | Training cartridge | |
| GB0615750D0 (en) | Aglet | |
| EP2274447A4 (en) | NEW DIVERGENT PICORNAVIRUS: COSAVIRUS | |
| GB0801764D0 (en) | A gun case | |
| ZA200900827B (en) | Miniature detonator | |
| GB0719982D0 (en) | Bombs | |
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| GB0601059D0 (en) | Target | |
| GB2448785B (en) | Improved dart |