PT2152735E - Método para produzir um vwf maturo a partir de um pró- péptido do vwf - Google Patents

Método para produzir um vwf maturo a partir de um pró- péptido do vwf Download PDF

Info

Publication number
PT2152735E
PT2152735E PT87545042T PT08754504T PT2152735E PT 2152735 E PT2152735 E PT 2152735E PT 87545042 T PT87545042 T PT 87545042T PT 08754504 T PT08754504 T PT 08754504T PT 2152735 E PT2152735 E PT 2152735E
Authority
PT
Portugal
Prior art keywords
vwf
peptide
pro
producing mature
producing
Prior art date
Application number
PT87545042T
Other languages
English (en)
Portuguese (pt)
Inventor
Wolfgang Mundt
Artur Mitterer
Meinhard Hasslacher
Christa Mayer
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of PT2152735E publication Critical patent/PT2152735E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT87545042T 2007-05-18 2008-05-16 Método para produzir um vwf maturo a partir de um pró- péptido do vwf PT2152735E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93089107P 2007-05-18 2007-05-18

Publications (1)

Publication Number Publication Date
PT2152735E true PT2152735E (pt) 2015-07-21

Family

ID=39666205

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87545042T PT2152735E (pt) 2007-05-18 2008-05-16 Método para produzir um vwf maturo a partir de um pró- péptido do vwf

Country Status (16)

Country Link
US (1) US8058411B2 (enExample)
EP (1) EP2152735B1 (enExample)
JP (2) JP5053435B2 (enExample)
KR (1) KR101156263B1 (enExample)
CN (1) CN101679496B (enExample)
AU (1) AU2008254522B2 (enExample)
BR (1) BRPI0811649B8 (enExample)
CA (1) CA2684151A1 (enExample)
DK (1) DK2152735T3 (enExample)
ES (1) ES2539284T3 (enExample)
HU (1) HUE025257T2 (enExample)
MX (1) MX2009012387A (enExample)
NZ (1) NZ581582A (enExample)
PL (1) PL2152735T3 (enExample)
PT (1) PT2152735E (enExample)
WO (1) WO2008143977A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG191186A1 (en) * 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
US20140276101A1 (en) * 2013-03-14 2014-09-18 Boston Scientific Scimed, Inc. Medical device for detecting a target and related methods of use
TWI666319B (zh) * 2014-08-12 2019-07-21 美商巴克斯歐塔公司 在分泌ｆｕｒｉｎ之哺乳動物表現系統中生產經完全加工且具功能性之因子Ｘ
CN111183151B (zh) 2017-06-23 2024-06-07 武田药品工业株式会社 因子viii亚种的纯化
MX2020009788A (es) * 2018-03-21 2020-12-09 Takeda Pharmaceuticals Co Separación de factor de von willebrand (vwf) y propéptido de factor de von willebrand (vwf) por métodos cromatográficos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
AT407750B (de) 1999-02-19 2001-05-25 Immuno Ag Verfahren zur herstellung einer vwf-präparation
KR20070092754A (ko) * 2004-12-27 2007-09-13 백스터 인터내셔널 인코포레이티드 중합체 - 폰 빌레브란트 인자 - 접합체

Also Published As

Publication number Publication date
HK1144577A1 (en) 2011-02-25
AU2008254522A2 (en) 2010-02-18
EP2152735B1 (en) 2015-03-18
JP5053435B2 (ja) 2012-10-17
BRPI0811649A2 (pt) 2014-11-11
DK2152735T3 (en) 2015-04-20
CA2684151A1 (en) 2008-11-27
PL2152735T3 (pl) 2015-08-31
JP2010527588A (ja) 2010-08-19
US8058411B2 (en) 2011-11-15
EP2152735A1 (en) 2010-02-17
NZ581582A (en) 2012-02-24
HUE025257T2 (en) 2016-03-29
US20090029918A1 (en) 2009-01-29
JP2012210226A (ja) 2012-11-01
BRPI0811649B1 (pt) 2020-11-17
KR101156263B1 (ko) 2012-06-13
BRPI0811649B8 (pt) 2021-05-25
KR20100028042A (ko) 2010-03-11
MX2009012387A (es) 2010-02-10
AU2008254522A1 (en) 2008-11-27
WO2008143977A1 (en) 2008-11-27
ES2539284T3 (es) 2015-06-29
AU2008254522B2 (en) 2012-07-12
CN101679496B (zh) 2013-03-13
CN101679496A (zh) 2010-03-24

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