PT2133330E - Atropisómero de derivado de pirrole - Google Patents
Atropisómero de derivado de pirrole Download PDFInfo
- Publication number
- PT2133330E PT2133330E PT87400107T PT08740010T PT2133330E PT 2133330 E PT2133330 E PT 2133330E PT 87400107 T PT87400107 T PT 87400107T PT 08740010 T PT08740010 T PT 08740010T PT 2133330 E PT2133330 E PT 2133330E
- Authority
- PT
- Portugal
- Prior art keywords
- atropisomer
- pyrrole derivative
- pyrrole
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007101938 | 2007-04-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2133330E true PT2133330E (pt) | 2014-03-31 |
Family
ID=39863928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT87400107T PT2133330E (pt) | 2007-04-09 | 2008-04-08 | Atropisómero de derivado de pirrole |
Country Status (15)
Country | Link |
---|---|
US (2) | US8524918B2 (pt) |
EP (1) | EP2133330B1 (pt) |
JP (1) | JP5363312B2 (pt) |
KR (2) | KR101477579B1 (pt) |
CN (1) | CN101679243B (pt) |
BR (1) | BRPI0809656B8 (pt) |
CA (1) | CA2683059C (pt) |
DK (1) | DK2133330T3 (pt) |
ES (1) | ES2448498T3 (pt) |
HK (1) | HK1139942A1 (pt) |
IL (1) | IL201261A0 (pt) |
PL (1) | PL2133330T3 (pt) |
PT (1) | PT2133330E (pt) |
TW (1) | TWI444185B (pt) |
WO (1) | WO2008126831A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010042622A1 (en) * | 2008-10-08 | 2010-04-15 | Exelixis, Inc. | Atropisomers of (hydroxyalkyl) pyrrole derivatives |
AU2009302375B2 (en) | 2008-10-08 | 2015-03-26 | Exelixis, Inc. | 1-phenylpyrrole compounds |
WO2010098286A1 (ja) * | 2009-02-25 | 2010-09-02 | 第一三共株式会社 | ミネラルコルチコイド受容体拮抗薬を含有する医薬 |
EP2411375B1 (en) * | 2009-03-26 | 2013-08-28 | Poxel | Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization |
CA2908879C (en) | 2013-04-10 | 2018-05-15 | Daiichi Sankyo Company, Limited | Crystal of pyrrole derivative and method for producing the same |
ES2847904T3 (es) * | 2013-07-23 | 2021-08-04 | Daiichi Sankyo Co Ltd | Medicamento para la prevención o el tratamiento de la hipertensión |
EP3040330B1 (en) * | 2013-08-27 | 2018-01-10 | Daiichi Sankyo Company, Limited | Method for producing pyrrole derivative, and intermediate thereof |
RS58274B1 (sr) | 2014-06-30 | 2019-03-29 | Astrazeneca Ab | Benzoksazinon amidi kao modulatori mineralokortikoidnog receptora |
KR102488167B1 (ko) * | 2015-01-26 | 2023-01-12 | 다이이찌 산쿄 가부시키가이샤 | 피롤카르복사미드의 고형 조성물 |
CN109053608A (zh) * | 2015-02-17 | 2018-12-21 | 华润赛科药业有限责任公司 | 一种旋光纯的硫代乙酸类化合物、其药物组合物和用途 |
CN105622531A (zh) | 2015-04-03 | 2016-06-01 | 南京明德新药研发股份有限公司 | 轴手性异构体及其制备方法和制药用途 |
JP6835836B2 (ja) | 2015-10-13 | 2021-02-24 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 脈絡膜血管新生の処置のための方法及び医薬組成物 |
EP3434284A4 (en) * | 2016-03-24 | 2019-11-13 | Daiichi Sankyo Company, Limited | MEDICINE FOR THE TREATMENT OF KIDNEY DISEASE |
US20190262363A1 (en) | 2016-07-26 | 2019-08-29 | INSERM (Institut National de la Santé et de la Recherche Médicale | Antagonist of mineralocorticoid receptor for the treatment of osteoarthritis |
AU2020371836A1 (en) | 2019-10-25 | 2021-11-11 | Sunshine Lake Pharma Co., Ltd. | Pyrrole amide compound and use thereof |
EP4118235A1 (en) | 2020-03-11 | 2023-01-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of determining whether a subject has or is at risk of having a central serous chorioretinopathy |
AU2022248168A1 (en) * | 2021-03-30 | 2023-10-05 | Sunshine Lake Pharma Co., Ltd. | Crystalline form of pyrrole amide compound, preparation method therefor and use thereof |
AU2022264993A1 (en) * | 2021-04-26 | 2023-11-09 | Sunshine Lake Pharma Co., Ltd. | Preparation method for pyrrole amide compound |
WO2023031277A1 (en) | 2021-08-31 | 2023-03-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment of ocular rosacea |
CN115784961A (zh) * | 2021-09-10 | 2023-03-14 | 上海鼎雅药物化学科技有限公司 | 埃沙西林酮及其中间体的合成方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6323208B1 (en) | 1997-09-05 | 2001-11-27 | Pfizer Inc | Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones |
US20040267028A1 (en) * | 2001-09-24 | 2004-12-30 | Smith Roger A | Preparation and use of pyrrole derivatives for treating obesity |
US6939968B2 (en) | 2002-12-23 | 2005-09-06 | Bristol-Myers Squibb Company | Atropisomers of 3-substituted-4-arylquinolin-2-one derivatives |
DE10354060A1 (de) * | 2003-11-19 | 2005-06-02 | Merck Patent Gmbh | Pyrrolderivate |
HUE041596T2 (hu) * | 2004-07-30 | 2019-05-28 | Exelixis Inc | Pirrol származékok mint gyógyászati szerek |
CA2593156C (en) * | 2005-01-10 | 2015-05-05 | Exelixis, Inc. | Heterocyclic carboxamide compounds as steroid nuclear receptors ligands |
-
2008
- 2008-04-08 EP EP08740010.7A patent/EP2133330B1/en active Active
- 2008-04-08 ES ES08740010.7T patent/ES2448498T3/es active Active
- 2008-04-08 DK DK08740010.7T patent/DK2133330T3/da active
- 2008-04-08 KR KR1020097021007A patent/KR101477579B1/ko active IP Right Grant
- 2008-04-08 KR KR1020147007688A patent/KR20140048337A/ko not_active Application Discontinuation
- 2008-04-08 TW TW097112578A patent/TWI444185B/zh active
- 2008-04-08 CA CA2683059A patent/CA2683059C/en active Active
- 2008-04-08 PL PL08740010T patent/PL2133330T3/pl unknown
- 2008-04-08 BR BRPI0809656A patent/BRPI0809656B8/pt active IP Right Grant
- 2008-04-08 CN CN200880011200XA patent/CN101679243B/zh active Active
- 2008-04-08 PT PT87400107T patent/PT2133330E/pt unknown
- 2008-04-08 WO PCT/JP2008/056907 patent/WO2008126831A1/ja active Application Filing
- 2008-04-08 JP JP2009509342A patent/JP5363312B2/ja active Active
-
2009
- 2009-09-30 IL IL201261A patent/IL201261A0/en active IP Right Grant
- 2009-10-08 US US12/576,091 patent/US8524918B2/en active Active
-
2010
- 2010-07-07 HK HK10106582.9A patent/HK1139942A1/xx unknown
-
2013
- 2013-07-30 US US13/954,753 patent/US8754118B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20140048337A (ko) | 2014-04-23 |
CN101679243B (zh) | 2012-09-26 |
JPWO2008126831A1 (ja) | 2010-07-22 |
US20100093826A1 (en) | 2010-04-15 |
KR101477579B1 (ko) | 2014-12-30 |
US8524918B2 (en) | 2013-09-03 |
TW200901968A (en) | 2009-01-16 |
EP2133330A4 (en) | 2010-08-11 |
JP5363312B2 (ja) | 2013-12-11 |
ES2448498T3 (es) | 2014-03-14 |
TWI444185B (zh) | 2014-07-11 |
BRPI0809656B8 (pt) | 2021-05-25 |
IL201261A0 (en) | 2010-05-31 |
BRPI0809656A2 (pt) | 2014-10-07 |
KR20090127421A (ko) | 2009-12-11 |
EP2133330B1 (en) | 2014-01-01 |
PL2133330T3 (pl) | 2014-06-30 |
CN101679243A (zh) | 2010-03-24 |
HK1139942A1 (en) | 2010-09-30 |
US20140024696A1 (en) | 2014-01-23 |
BRPI0809656B1 (pt) | 2019-07-09 |
WO2008126831A1 (ja) | 2008-10-23 |
US8754118B2 (en) | 2014-06-17 |
DK2133330T3 (da) | 2014-03-31 |
CA2683059A1 (en) | 2008-10-23 |
EP2133330A1 (en) | 2009-12-16 |
CA2683059C (en) | 2012-09-25 |
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