PT2057125E - Inibidores n?o nucle?sidos de transcriptase inversa - Google Patents

Inibidores n?o nucle?sidos de transcriptase inversa Download PDF

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Publication number
PT2057125E
PT2057125E PT07802503T PT07802503T PT2057125E PT 2057125 E PT2057125 E PT 2057125E PT 07802503 T PT07802503 T PT 07802503T PT 07802503 T PT07802503 T PT 07802503T PT 2057125 E PT2057125 E PT 2057125E
Authority
PT
Portugal
Prior art keywords
reverse transcriptase
transcriptase inhibitors
nucleoside reverse
nucleoside
inhibitors
Prior art date
Application number
PT07802503T
Other languages
English (en)
Inventor
Wylie Solang Palmer
Joshua Kennedy-Smith
Zachary Kevin Sweeney
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT2057125E publication Critical patent/PT2057125E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT07802503T 2006-08-16 2007-08-06 Inibidores n?o nucle?sidos de transcriptase inversa PT2057125E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83827206P 2006-08-16 2006-08-16

Publications (1)

Publication Number Publication Date
PT2057125E true PT2057125E (pt) 2011-05-31

Family

ID=38663155

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07802503T PT2057125E (pt) 2006-08-16 2007-08-06 Inibidores n?o nucle?sidos de transcriptase inversa

Country Status (23)

Country Link
US (2) US7713974B2 (pt)
EP (1) EP2057125B1 (pt)
JP (1) JP5216768B2 (pt)
KR (1) KR101401811B1 (pt)
CN (1) CN101501002B (pt)
AR (1) AR062366A1 (pt)
AT (1) ATE503744T1 (pt)
AU (1) AU2007286345B2 (pt)
BR (1) BRPI0715193A2 (pt)
CA (1) CA2658984C (pt)
CL (1) CL2007002346A1 (pt)
DE (1) DE602007013573D1 (pt)
DK (1) DK2057125T3 (pt)
ES (1) ES2360893T3 (pt)
IL (1) IL196655A (pt)
MX (1) MX2009001198A (pt)
NO (1) NO20090405L (pt)
PE (1) PE20080734A1 (pt)
PL (1) PL2057125T3 (pt)
PT (1) PT2057125E (pt)
RU (1) RU2451676C2 (pt)
TW (1) TWI417293B (pt)
WO (1) WO2008019968A1 (pt)

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CN106614663A (zh) * 2016-12-29 2017-05-10 新沂市中诺新材料科技有限公司 一种新型纳米级吲唑类农药合成方法
CN113511960A (zh) * 2021-08-20 2021-10-19 郑州华赞医药科技有限公司 一种1-氯-3-甲氧基-5-甲基苯的合成方法

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Also Published As

Publication number Publication date
JP2010500392A (ja) 2010-01-07
IL196655A0 (en) 2009-11-18
EP2057125A1 (en) 2009-05-13
IL196655A (en) 2012-09-24
CL2007002346A1 (es) 2008-03-14
CN101501002A (zh) 2009-08-05
BRPI0715193A2 (pt) 2013-10-01
CN101501002B (zh) 2012-06-27
US8063064B2 (en) 2011-11-22
EP2057125B1 (en) 2011-03-30
DE602007013573D1 (de) 2011-05-12
JP5216768B2 (ja) 2013-06-19
US20110059975A1 (en) 2011-03-10
TWI417293B (zh) 2013-12-01
ES2360893T3 (es) 2011-06-10
RU2451676C2 (ru) 2012-05-27
PL2057125T3 (pl) 2011-09-30
AU2007286345A1 (en) 2008-02-21
ATE503744T1 (de) 2011-04-15
RU2009109354A (ru) 2010-09-27
CA2658984C (en) 2014-12-02
TW200817397A (en) 2008-04-16
KR20090040438A (ko) 2009-04-24
CA2658984A1 (en) 2008-02-21
KR101401811B1 (ko) 2014-05-29
WO2008019968A1 (en) 2008-02-21
NO20090405L (no) 2009-01-30
US20080045511A1 (en) 2008-02-21
US7713974B2 (en) 2010-05-11
AR062366A1 (es) 2008-11-05
PE20080734A1 (es) 2008-06-14
MX2009001198A (es) 2009-02-11
DK2057125T3 (da) 2011-05-16
AU2007286345B2 (en) 2012-03-08

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