PT1474417E - Processos para preparacao de losartan e losartan potassico - Google Patents

Processos para preparacao de losartan e losartan potassico

Info

Publication number
PT1474417E
PT1474417E PT03726536T PT03726536T PT1474417E PT 1474417 E PT1474417 E PT 1474417E PT 03726536 T PT03726536 T PT 03726536T PT 03726536 T PT03726536 T PT 03726536T PT 1474417 E PT1474417 E PT 1474417E
Authority
PT
Portugal
Prior art keywords
losartan
alcohol
triarylmethyl
potassium
potassico
Prior art date
Application number
PT03726536T
Other languages
English (en)
Inventor
Dolitzky Ben-Zion
Nisnevich Gennady
Rukhman Igor
Kaftanov Julia
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of PT1474417E publication Critical patent/PT1474417E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
PT03726536T 2002-04-29 2003-04-29 Processos para preparacao de losartan e losartan potassico PT1474417E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37632202P 2002-04-29 2002-04-29

Publications (1)

Publication Number Publication Date
PT1474417E true PT1474417E (pt) 2006-06-30

Family

ID=29401331

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03726536T PT1474417E (pt) 2002-04-29 2003-04-29 Processos para preparacao de losartan e losartan potassico

Country Status (10)

Country Link
US (1) US7041832B2 (pt)
EP (1) EP1474417B1 (pt)
AT (1) ATE321039T1 (pt)
AU (1) AU2003228767A1 (pt)
CA (1) CA2482857A1 (pt)
DE (1) DE60304175T2 (pt)
ES (1) ES2259412T3 (pt)
IL (1) IL164902A0 (pt)
PT (1) PT1474417E (pt)
WO (1) WO2003093262A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7345071B2 (en) 2003-05-07 2008-03-18 Ipca Laboratories Limited Process for the synthesis of Losartan potassium
EP1709034A2 (en) * 2004-01-06 2006-10-11 IPCA Laboratories Limited An improved process for the synthesis of losartan potassium
DE502006004733D1 (de) 2005-02-03 2009-10-15 Ratiopharm Gmbh Verfahren zur herstellung von losartan
WO2006097121A1 (en) * 2005-03-16 2006-09-21 Ulkar Kimya Sanayii Ve Ticaret A.S. Method for producing biphenyl-tetrazole compounds
US20090076281A1 (en) * 2005-05-05 2009-03-19 Medichem, S.A. Process for the preparation of losartan and its salts
EP1741711A1 (en) * 2005-07-04 2007-01-10 KRKA, D.D., Novo Mesto A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1H-imidazole-5-carbaldehydes
ATE487711T1 (de) * 2005-12-01 2010-11-15 Ulkar Kimya Sanayii Ve Ticaret Verfahren zur herstellung von metallsalzen von losartan
KR20100021454A (ko) * 2007-06-15 2010-02-24 도꾜 다이가꾸 주쇄 골격이 ―Ｓｉ―Ｏ―로 본질적으로 이루어지는 폴리로탁산 및 그의 제조 방법, 및 상기 폴리로탁산을 가교시켜 이루어지는 가교 폴리로탁산 및 그의 제조 방법
CN108047208B (zh) * 2018-01-12 2022-03-22 浙江华海药业股份有限公司 一种降低氯沙坦二聚物杂质的方法
US11327065B1 (en) * 2021-08-27 2022-05-10 Jubilant Generics Limited Preparation of angiotensin receptor blockers or pharmaceutically acceptable salts thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
JPS5671073A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd Imidazole derivative
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
SG59988A1 (en) * 1987-09-04 1999-02-22 Beecham Group Plc Substituted thiazolidinedione derivatives
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
US5155188A (en) * 1988-12-29 1992-10-13 The B. F. Goodrich Company Oxide cocatalysts in ring opening polymerization of polycycloolefins
US5332744A (en) * 1989-05-30 1994-07-26 Merck & Co., Inc. Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
US5187069A (en) 1990-08-06 1993-02-16 Henry Ford Health System Active site labelling of plasminogen
GB9017482D0 (en) 1990-08-09 1990-09-26 Ici Plc Manufacturing process
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
US5130439A (en) * 1991-11-18 1992-07-14 Lo Young S Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists
US5484955A (en) * 1992-07-06 1996-01-16 Takeda Chemical Industries, Ltd. Tri-higher alkyl tin azide and its use
AU685898B2 (en) * 1993-12-23 1998-01-29 Du Pont Merck Pharmaceutical Company, The Polymorphs of losartan and the process for the preparation of form II of losartan
WO1995026188A1 (en) * 1994-03-29 1995-10-05 Merck & Co., Inc. Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
GB9406573D0 (en) * 1994-03-31 1994-05-25 Merck Sharp & Dohme Medicaments
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
HU222773B1 (hu) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás egy ismert tetrazolszármazék előállítására
BR0102252B1 (pt) 2001-04-10 2013-10-22 Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso

Also Published As

Publication number Publication date
EP1474417A2 (en) 2004-11-10
WO2003093262A3 (en) 2004-03-18
AU2003228767A1 (en) 2003-11-17
IL164902A0 (en) 2005-12-18
DE60304175T2 (de) 2007-03-15
CA2482857A1 (en) 2003-11-13
ATE321039T1 (de) 2006-04-15
US20040034077A1 (en) 2004-02-19
EP1474417B1 (en) 2006-03-22
US7041832B2 (en) 2006-05-09
DE60304175D1 (de) 2006-05-11
ES2259412T3 (es) 2006-10-01
WO2003093262A2 (en) 2003-11-13

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