PT1370513E - Sais de adicao do acido malico de terbinafina - Google Patents

Sais de adicao do acido malico de terbinafina

Info

Publication number
PT1370513E
PT1370513E PT02704689T PT02704689T PT1370513E PT 1370513 E PT1370513 E PT 1370513E PT 02704689 T PT02704689 T PT 02704689T PT 02704689 T PT02704689 T PT 02704689T PT 1370513 E PT1370513 E PT 1370513E
Authority
PT
Portugal
Prior art keywords
malic acid
salts
terbinafin
antimycotics
compound
Prior art date
Application number
PT02704689T
Other languages
English (en)
Inventor
Danielle Giron
Stefan Hirsch
Reber Jean-Louis
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1370513E publication Critical patent/PT1370513E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
PT02704689T 2001-02-07 2002-02-06 Sais de adicao do acido malico de terbinafina PT1370513E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0103046.9A GB0103046D0 (en) 2001-02-07 2001-02-07 Organic Compounds

Publications (1)

Publication Number Publication Date
PT1370513E true PT1370513E (pt) 2005-08-31

Family

ID=9908301

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02704689T PT1370513E (pt) 2001-02-07 2002-02-06 Sais de adicao do acido malico de terbinafina

Country Status (28)

Country Link
US (2) US20040147603A1 (pt)
EP (1) EP1370513B1 (pt)
JP (1) JP4078206B2 (pt)
KR (2) KR100859609B1 (pt)
CN (1) CN1216034C (pt)
AT (1) ATE294154T1 (pt)
AU (1) AU2002238534C1 (pt)
BR (1) BR0207077A (pt)
CA (1) CA2437592A1 (pt)
CZ (1) CZ20032132A3 (pt)
DE (1) DE60203890T2 (pt)
DK (1) DK1370513T3 (pt)
EC (1) ECSP034713A (pt)
ES (1) ES2240698T3 (pt)
GB (1) GB0103046D0 (pt)
HK (1) HK1060876A1 (pt)
HU (1) HUP0303174A3 (pt)
IL (2) IL157241A0 (pt)
MX (1) MXPA03007072A (pt)
NO (1) NO20033473L (pt)
NZ (1) NZ527300A (pt)
PL (1) PL204812B1 (pt)
PT (1) PT1370513E (pt)
RU (1) RU2289570C2 (pt)
SI (1) SI1370513T1 (pt)
SK (1) SK9992003A3 (pt)
WO (1) WO2002070455A1 (pt)
ZA (1) ZA200306029B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538067A (ja) * 2002-07-02 2005-12-15 ノバルティス アクチエンゲゼルシャフト 副鼻腔炎の処置方法
GB0503942D0 (en) * 2005-02-25 2005-04-06 Novartis Ag Purification process
WO2007104474A1 (en) * 2006-03-10 2007-09-20 Novartis Ag Antifungal compositions comprising (1) a salt of terbinafine with malic acid and (2) malic acid
WO2007147052A2 (en) * 2006-06-14 2007-12-21 Dr. Reddy's Laboratories Limited Topical compositions
NZ618004A (en) 2009-01-16 2015-06-26 Exelixis Inc Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
CN106106449A (zh) * 2016-06-21 2016-11-16 广西中烟工业有限责任公司 特比萘芬制剂及其在提高烟叶角鲨烯含量中的应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507755A (en) * 1967-10-17 1970-04-21 Bayer Ag Process for the purification of acrylonitrile by distillation with side stream withdrawal and decantation
US4276125A (en) 1979-02-02 1981-06-30 Asahi Kasei Kogyo Kabushiki Kaisha Process for purification of crude olefinically unsaturated nitrile and condenser useful for same process
US4269667A (en) 1979-08-02 1981-05-26 Standard Oil Company Acrylonitrile purification by extractive distillation
EP0024587B1 (en) * 1979-08-22 1984-11-14 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
KR850001603B1 (ko) 1980-12-03 1985-10-24 아사히 가세이 고오교오 가부시기가이샤 불포화 니트릴의 제조법
GB8608335D0 (en) 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
NZ227042A (en) * 1987-11-27 1991-05-28 Banyu Pharma Co Ltd Substituted alkylamine derivatives and pharmaceutical compositions
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU219480B (hu) 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
US5461068A (en) * 1993-09-29 1995-10-24 Corwood Laboratories, Inc. Imidazole derivative tincture and method of manufacture
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
NZ280065A (en) * 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives
BR9811458A (pt) * 1997-03-31 2000-09-19 Johnson & Johnson Consumer "sistema solvente para penetração melhorada de compostos farmacêuticos"
US6231875B1 (en) 1998-03-31 2001-05-15 Johnson & Johnson Consumer Companies, Inc. Acidified composition for topical treatment of nail and skin conditions
WO1999049895A2 (en) 1998-03-31 1999-10-07 Johnson And Johnson Consumer Companies, Inc. Method for increasing the permeability of horny human tissue
EP1113785B1 (en) * 1998-07-24 2005-04-13 Seo Hong Yoo Clear aqueous solutions of bile acids
JP2000053681A (ja) 1998-08-10 2000-02-22 Sankyo Co Ltd 三環性複素環化合物を含有する抗菌剤
SK286804B6 (sk) * 1999-10-22 2009-05-07 Richter Gedeon Vegy�Szeti Gy�R Rt. Spôsob prípravy substituovaného derivátu alylamínu a jeho solí
GB0014448D0 (en) 2000-06-13 2000-08-09 Novartis Ag Organic compounds
JP4899139B2 (ja) 2000-08-10 2012-03-21 株式会社ポーラファルマ 抗真菌医薬組成物
JP4803511B2 (ja) 2000-08-25 2011-10-26 株式会社ポーラファルマ 抗真菌医薬組成物
JP2002068975A (ja) 2000-08-25 2002-03-08 Pola Chem Ind Inc 抗真菌医薬組成物

Also Published As

Publication number Publication date
MXPA03007072A (es) 2003-11-18
NO20033473D0 (no) 2003-08-05
ES2240698T3 (es) 2005-10-16
ZA200306029B (en) 2004-06-28
NO20033473L (no) 2003-09-17
HUP0303174A2 (hu) 2003-12-29
KR20080041756A (ko) 2008-05-13
US20070088084A1 (en) 2007-04-19
IL157241A (en) 2009-06-15
CN1491206A (zh) 2004-04-21
RU2003126176A (ru) 2005-03-10
KR20030077606A (ko) 2003-10-01
ATE294154T1 (de) 2005-05-15
IL157241A0 (en) 2004-02-19
CN1216034C (zh) 2005-08-24
RU2289570C2 (ru) 2006-12-20
CA2437592A1 (en) 2002-09-12
GB0103046D0 (en) 2001-03-21
BR0207077A (pt) 2004-01-20
DK1370513T3 (da) 2005-08-01
AU2002238534C1 (en) 2006-04-13
ECSP034713A (es) 2003-09-24
EP1370513A1 (en) 2003-12-17
AU2002238534B2 (en) 2005-09-29
SK9992003A3 (en) 2004-01-08
HK1060876A1 (en) 2004-08-27
JP4078206B2 (ja) 2008-04-23
CZ20032132A3 (cs) 2003-10-15
KR100859609B1 (ko) 2008-09-23
DE60203890D1 (de) 2005-06-02
NZ527300A (en) 2005-02-25
PL204812B1 (pl) 2010-02-26
EP1370513B1 (en) 2005-04-27
PL362554A1 (en) 2004-11-02
US20040147603A1 (en) 2004-07-29
DE60203890T2 (de) 2006-01-19
WO2002070455A1 (en) 2002-09-12
US7488759B2 (en) 2009-02-10
HUP0303174A3 (en) 2008-03-28
JP2004523567A (ja) 2004-08-05
SI1370513T1 (en) 2005-10-31

Similar Documents

Publication Publication Date Title
AP1614A (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents.
SE0302811D0 (sv) Novel compounds
CY1106247T1 (el) Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
ATE433447T1 (de) Pyrimiidinverbindungen
DE60230890D1 (de) Indolizine als kinaseproteinhemmer
NO20062644L (no) DPP-IV inhibitorer
ECSP034850A (es) Sal citrato de 5, 8, 14-triazatetraciclo [10.3.1.02,11.04,9] hexadeca-2 (11),3,5,7,9-pentaeno y composiciones farmaceuticas de la misma
DE60314623D1 (de) Substituierte pyrazolopyrimidine
UA91002C2 (ru) 7-фенилалкилзамещенные 2-хинолиноны и 2-хиноксалиноны как ингибиторы поле(адф-рибоза)полимеразы
WO2007067559A3 (en) Antibacterial agents
TW200716529A (en) New compounds II
MY153763A (en) Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof
ES2421948T3 (es) Compuestos y composiciones para suministrar agentes activos
UA96759C2 (en) 2-ARYLINDOLE DERIVATIVES AS mPGES-I INHIBITORS
ECSP044999A (es) Agentes antidiabeticos
DK1531672T3 (da) Antimikrobielle sammensætninger
DK1670778T3 (da) Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende
TW200744612A (en) New combination
PT1370513E (pt) Sais de adicao do acido malico de terbinafina
WO2006023586A3 (en) Guanylhydrazone compounds, compositions, methods of making and using
ATE274515T1 (de) Pyrazolopyridinderivate
TW200745053A (en) 9-Aminocarbonylsubstituted derivatives of glycylcyclines
DOP2002000386A (es) Agentes antibacterianos
SE0001631D0 (sv) New use
SV2003001058A (es) Agentes antibacterianos pca494-01