DK1370513T3 - Æblesyreadditionssalte af terbinafin - Google Patents

Æblesyreadditionssalte af terbinafin

Info

Publication number
DK1370513T3
DK1370513T3 DK02704689T DK02704689T DK1370513T3 DK 1370513 T3 DK1370513 T3 DK 1370513T3 DK 02704689 T DK02704689 T DK 02704689T DK 02704689 T DK02704689 T DK 02704689T DK 1370513 T3 DK1370513 T3 DK 1370513T3
Authority
DK
Denmark
Prior art keywords
malic
terbinafine
addition salts
antimycotics
compound
Prior art date
Application number
DK02704689T
Other languages
Danish (da)
English (en)
Inventor
Danielle Giron
Jean-Louis Reber
Stefan Hirsch
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1370513T3 publication Critical patent/DK1370513T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
DK02704689T 2001-02-07 2002-02-06 Æblesyreadditionssalte af terbinafin DK1370513T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0103046.9A GB0103046D0 (en) 2001-02-07 2001-02-07 Organic Compounds
PCT/EP2002/001249 WO2002070455A1 (en) 2001-02-07 2002-02-06 Malic acid addition salts of terbinafine
EP02704689A EP1370513B1 (en) 2001-02-07 2002-02-06 Malic acid addition salts of terbinafine

Publications (1)

Publication Number Publication Date
DK1370513T3 true DK1370513T3 (da) 2005-08-01

Family

ID=9908301

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02704689T DK1370513T3 (da) 2001-02-07 2002-02-06 Æblesyreadditionssalte af terbinafin

Country Status (28)

Country Link
US (2) US20040147603A1 (pt)
EP (1) EP1370513B1 (pt)
JP (1) JP4078206B2 (pt)
KR (2) KR100859609B1 (pt)
CN (1) CN1216034C (pt)
AT (1) ATE294154T1 (pt)
AU (1) AU2002238534C1 (pt)
BR (1) BR0207077A (pt)
CA (1) CA2437592A1 (pt)
CZ (1) CZ20032132A3 (pt)
DE (1) DE60203890T2 (pt)
DK (1) DK1370513T3 (pt)
EC (1) ECSP034713A (pt)
ES (1) ES2240698T3 (pt)
GB (1) GB0103046D0 (pt)
HK (1) HK1060876A1 (pt)
HU (1) HUP0303174A3 (pt)
IL (2) IL157241A0 (pt)
MX (1) MXPA03007072A (pt)
NO (1) NO20033473L (pt)
NZ (1) NZ527300A (pt)
PL (1) PL204812B1 (pt)
PT (1) PT1370513E (pt)
RU (1) RU2289570C2 (pt)
SI (1) SI1370513T1 (pt)
SK (1) SK9992003A3 (pt)
WO (1) WO2002070455A1 (pt)
ZA (1) ZA200306029B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538067A (ja) * 2002-07-02 2005-12-15 ノバルティス アクチエンゲゼルシャフト 副鼻腔炎の処置方法
GB0503942D0 (en) * 2005-02-25 2005-04-06 Novartis Ag Purification process
WO2007104474A1 (en) * 2006-03-10 2007-09-20 Novartis Ag Antifungal compositions comprising (1) a salt of terbinafine with malic acid and (2) malic acid
WO2007147052A2 (en) * 2006-06-14 2007-12-21 Dr. Reddy's Laboratories Limited Topical compositions
NZ618004A (en) 2009-01-16 2015-06-26 Exelixis Inc Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
CN106106449A (zh) * 2016-06-21 2016-11-16 广西中烟工业有限责任公司 特比萘芬制剂及其在提高烟叶角鲨烯含量中的应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507755A (en) * 1967-10-17 1970-04-21 Bayer Ag Process for the purification of acrylonitrile by distillation with side stream withdrawal and decantation
US4276125A (en) 1979-02-02 1981-06-30 Asahi Kasei Kogyo Kabushiki Kaisha Process for purification of crude olefinically unsaturated nitrile and condenser useful for same process
US4269667A (en) 1979-08-02 1981-05-26 Standard Oil Company Acrylonitrile purification by extractive distillation
EP0024587B1 (en) * 1979-08-22 1984-11-14 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
KR850001603B1 (ko) 1980-12-03 1985-10-24 아사히 가세이 고오교오 가부시기가이샤 불포화 니트릴의 제조법
GB8608335D0 (en) 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
NZ227042A (en) * 1987-11-27 1991-05-28 Banyu Pharma Co Ltd Substituted alkylamine derivatives and pharmaceutical compositions
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU219480B (hu) 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
US5461068A (en) * 1993-09-29 1995-10-24 Corwood Laboratories, Inc. Imidazole derivative tincture and method of manufacture
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
NZ280065A (en) * 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives
BR9811458A (pt) * 1997-03-31 2000-09-19 Johnson & Johnson Consumer "sistema solvente para penetração melhorada de compostos farmacêuticos"
US6231875B1 (en) 1998-03-31 2001-05-15 Johnson & Johnson Consumer Companies, Inc. Acidified composition for topical treatment of nail and skin conditions
WO1999049895A2 (en) 1998-03-31 1999-10-07 Johnson And Johnson Consumer Companies, Inc. Method for increasing the permeability of horny human tissue
EP1113785B1 (en) * 1998-07-24 2005-04-13 Seo Hong Yoo Clear aqueous solutions of bile acids
JP2000053681A (ja) 1998-08-10 2000-02-22 Sankyo Co Ltd 三環性複素環化合物を含有する抗菌剤
SK286804B6 (sk) * 1999-10-22 2009-05-07 Richter Gedeon Vegy�Szeti Gy�R Rt. Spôsob prípravy substituovaného derivátu alylamínu a jeho solí
GB0014448D0 (en) 2000-06-13 2000-08-09 Novartis Ag Organic compounds
JP4899139B2 (ja) 2000-08-10 2012-03-21 株式会社ポーラファルマ 抗真菌医薬組成物
JP4803511B2 (ja) 2000-08-25 2011-10-26 株式会社ポーラファルマ 抗真菌医薬組成物
JP2002068975A (ja) 2000-08-25 2002-03-08 Pola Chem Ind Inc 抗真菌医薬組成物

Also Published As

Publication number Publication date
MXPA03007072A (es) 2003-11-18
NO20033473D0 (no) 2003-08-05
ES2240698T3 (es) 2005-10-16
ZA200306029B (en) 2004-06-28
NO20033473L (no) 2003-09-17
PT1370513E (pt) 2005-08-31
HUP0303174A2 (hu) 2003-12-29
KR20080041756A (ko) 2008-05-13
US20070088084A1 (en) 2007-04-19
IL157241A (en) 2009-06-15
CN1491206A (zh) 2004-04-21
RU2003126176A (ru) 2005-03-10
KR20030077606A (ko) 2003-10-01
ATE294154T1 (de) 2005-05-15
IL157241A0 (en) 2004-02-19
CN1216034C (zh) 2005-08-24
RU2289570C2 (ru) 2006-12-20
CA2437592A1 (en) 2002-09-12
GB0103046D0 (en) 2001-03-21
BR0207077A (pt) 2004-01-20
AU2002238534C1 (en) 2006-04-13
ECSP034713A (es) 2003-09-24
EP1370513A1 (en) 2003-12-17
AU2002238534B2 (en) 2005-09-29
SK9992003A3 (en) 2004-01-08
HK1060876A1 (en) 2004-08-27
JP4078206B2 (ja) 2008-04-23
CZ20032132A3 (cs) 2003-10-15
KR100859609B1 (ko) 2008-09-23
DE60203890D1 (de) 2005-06-02
NZ527300A (en) 2005-02-25
PL204812B1 (pl) 2010-02-26
EP1370513B1 (en) 2005-04-27
PL362554A1 (en) 2004-11-02
US20040147603A1 (en) 2004-07-29
DE60203890T2 (de) 2006-01-19
WO2002070455A1 (en) 2002-09-12
US7488759B2 (en) 2009-02-10
HUP0303174A3 (en) 2008-03-28
JP2004523567A (ja) 2004-08-05
SI1370513T1 (en) 2005-10-31

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