PT1347743E - Composicao para o tratamento de doencas inflamatorias - Google Patents
Composicao para o tratamento de doencas inflamatoriasInfo
- Publication number
- PT1347743E PT1347743E PT01991836T PT01991836T PT1347743E PT 1347743 E PT1347743 E PT 1347743E PT 01991836 T PT01991836 T PT 01991836T PT 01991836 T PT01991836 T PT 01991836T PT 1347743 E PT1347743 E PT 1347743E
- Authority
- PT
- Portugal
- Prior art keywords
- vesicle
- treatment
- composition
- inflammatory diseases
- mole percent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/797—Lipid particle
- Y10S977/798—Lipid particle having internalized material
- Y10S977/799—Containing biological material
- Y10S977/801—Drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00204372 | 2000-12-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1347743E true PT1347743E (pt) | 2006-06-30 |
Family
ID=8172392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01991836T PT1347743E (pt) | 2000-12-07 | 2001-12-07 | Composicao para o tratamento de doencas inflamatorias |
Country Status (11)
Country | Link |
---|---|
US (1) | US7955618B2 (pt) |
EP (1) | EP1347743B1 (pt) |
JP (1) | JP4623931B2 (pt) |
AT (1) | ATE319428T1 (pt) |
AU (2) | AU2002231697B2 (pt) |
CA (1) | CA2430897C (pt) |
DE (1) | DE60117858T2 (pt) |
DK (1) | DK1347743T3 (pt) |
ES (1) | ES2260321T3 (pt) |
PT (1) | PT1347743E (pt) |
WO (1) | WO2002045688A2 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002231697B2 (en) | 2000-12-07 | 2006-09-07 | Enceladus Pharmaceuticals B.V. | Composition for treatment of inflammatory disorders |
US7635463B2 (en) * | 2002-02-27 | 2009-12-22 | Pharmain Corporation | Compositions for delivery of therapeutics and other materials |
EP1371362A1 (en) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition for treatment of inflammatory disorders |
EP1393720A1 (en) * | 2002-08-27 | 2004-03-03 | Universiteit Utrecht | Vesicle-encapsulated corticosteroids for treatment of cancer |
JPWO2005011633A1 (ja) * | 2003-08-01 | 2006-09-14 | 独立行政法人産業技術総合研究所 | 標的指向性リポソームを含む炎症性疾患治療薬または診断薬 |
US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
US8932627B2 (en) | 2004-09-09 | 2015-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal compositions of glucocorticoid and glucocorticoid derivatives |
CN106075449A (zh) * | 2005-07-14 | 2016-11-09 | 尼奥塞蒂克斯公司 | 用于局部脂肪组织治疗的持续释放的增强性脂肪分解性制剂 |
JP2010506941A (ja) * | 2006-10-17 | 2010-03-04 | リセラ,インク. | 甲状腺眼症の治療のための方法、組成物及び製剤 |
WO2009073146A2 (en) * | 2007-11-29 | 2009-06-11 | Celgene Corporation | Use of immunomodulatory compounds for the treatment of transverse myelitis, multiple sclerosis, and other disorders |
EP2127639A1 (en) * | 2008-05-26 | 2009-12-02 | Universiteit Utrecht Holding B.V. | Corticosteroid containing liposomes for treatment of cardiovascular diseases |
US20100016265A1 (en) * | 2008-07-16 | 2010-01-21 | Qaiser Yusuf | Anti-inflammatory composition and method for preparation |
US9132084B2 (en) * | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
KR101638301B1 (ko) * | 2010-01-15 | 2016-07-08 | 네오쎄틱스 인코포레이티드 | 동결건조 케이크 제제 |
CN105832681A (zh) | 2010-11-24 | 2016-08-10 | 纽赛蒂克斯公司 | 选择性、亲脂性及长效型β激动剂单一治疗调配物和用于肥胖及外形凸起的美容治疗的方法 |
PT2773325T (pt) * | 2011-11-04 | 2018-12-19 | Enceladus Pharmaceuticals B V | Corticosteróides lipossômicos para o tratamento de transtornos inflamatórios em humanos |
US9186326B2 (en) * | 2014-07-21 | 2015-11-17 | Kimia Zist Parsian (Kzp) | Method and system for synthesizing nanocarrier based long acting drug delivery system for dexamethasone |
CN108289845A (zh) * | 2015-09-14 | 2018-07-17 | 维吉思康科技公司 | 皮下、舌下和口服治疗用空间稳定载体、用于治疗哺乳动物的组合物和方法 |
CN109906075A (zh) | 2016-04-29 | 2019-06-18 | 恩瑟拉德斯医药有限公司 | 用于在发炎病灶或区域中局部注射的脂质体皮质类固醇 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
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US2002185A (en) * | 1930-06-26 | 1935-05-21 | Prosperity Co Inc | Garment or ironing press |
GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4994443A (en) * | 1982-12-20 | 1991-02-19 | The Children's Medical Center Corporation | Inhibition of angiogenesis |
US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
IL79114A (en) | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
DE3542773A1 (de) * | 1985-12-04 | 1987-06-11 | Roehm Pharma Gmbh | Hautwirksame pharmaka mit liposomen als wirkstofftraeger |
US4818537A (en) * | 1986-10-21 | 1989-04-04 | Liposome Technology, Inc. | Liposome composition for treating dry eye |
IL91664A (en) * | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
US5139803A (en) * | 1989-02-09 | 1992-08-18 | Nabisco, Inc. | Method and liposome composition for the stabilization of oxidizable substances |
FR2648462B1 (fr) * | 1989-06-15 | 1994-01-28 | Oreal | Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede |
US5356633A (en) * | 1989-10-20 | 1994-10-18 | Liposome Technology, Inc. | Method of treatment of inflamed tissues |
US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
US5474765A (en) * | 1992-03-23 | 1995-12-12 | Ut Sw Medical Ctr At Dallas | Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells |
US5989586A (en) | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
CA2120197A1 (en) * | 1993-04-02 | 1994-10-03 | Kenji Endo | Stable aqueous dispersions containing liposomes |
JPH07316040A (ja) * | 1994-03-29 | 1995-12-05 | Res Dev Corp Of Japan | 再構成リポソームと物質導入方法 |
US5786344A (en) * | 1994-07-05 | 1998-07-28 | Arch Development Corporation | Camptothecin drug combinations and methods with reduced side effects |
JPH08198777A (ja) * | 1995-01-25 | 1996-08-06 | Taisho Pharmaceut Co Ltd | 注射用脂肪乳剤 |
KR100506958B1 (ko) * | 1995-12-15 | 2005-10-27 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | 액정디스플레이 장치 |
JPH09278672A (ja) * | 1996-04-12 | 1997-10-28 | Green Cross Corp:The | 薬物含有脂肪乳剤 |
DK0850646T3 (da) * | 1996-06-18 | 2008-05-13 | Kyowa Hakko Kogyo Kk | Liposompræparater af indolocarbazol-derivater |
EP0929293B1 (en) * | 1996-08-23 | 2003-10-22 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
US6120751A (en) * | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
US5758659A (en) | 1997-03-26 | 1998-06-02 | Thompson; Robert B. | Wound tab condom and method of application |
WO1998050041A1 (en) | 1997-05-06 | 1998-11-12 | Imarx Pharmaceutical Corp. | Novel prodrugs comprising fluorinated amphiphiles |
US20020159951A1 (en) | 1997-05-06 | 2002-10-31 | Unger Evan C. | Novel targeted compositions for diagnostic and therapeutic use |
US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
US6316260B1 (en) * | 1997-08-22 | 2001-11-13 | Bernina Biosystems Gmbh | Tetraether lipid derivatives and liposomes and lipid agglomerates containing tetraether lipid derivatives, and use thereof |
WO2000025748A1 (fr) * | 1998-11-02 | 2000-05-11 | Terumo Kabushiki Kaisha | Liposomes |
CN1320880C (zh) | 1998-12-23 | 2007-06-13 | 伊迪亚股份公司 | 改进的体内局部无创伤用制剂 |
US6270806B1 (en) * | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
ES2327025T3 (es) | 1999-06-25 | 2009-10-23 | Terumo Kabushiki Kaisha | Liposomas. |
WO2001005873A1 (en) * | 1999-07-14 | 2001-01-25 | Alza Corporation | Neutral lipopolymer and liposomal compositions containing same |
EP1072617A1 (en) | 1999-07-30 | 2001-01-31 | Universiteit van Utrecht | Temperature sensitive polymers |
US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
US20030050236A1 (en) * | 2000-08-15 | 2003-03-13 | The University Of Chicago | Compounds that enhance tumor death |
TWI230616B (en) * | 2000-09-25 | 2005-04-11 | Ind Tech Res Inst | Liposome for incorporating large amounts of hydrophobic substances |
AU2002231697B2 (en) | 2000-12-07 | 2006-09-07 | Enceladus Pharmaceuticals B.V. | Composition for treatment of inflammatory disorders |
EP1371362A1 (en) | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition for treatment of inflammatory disorders |
US20050152962A1 (en) * | 2002-06-12 | 2005-07-14 | Metselaar Josbert M. | Composition for treatment of inflammatory disorders |
EP1393720A1 (en) | 2002-08-27 | 2004-03-03 | Universiteit Utrecht | Vesicle-encapsulated corticosteroids for treatment of cancer |
-
2001
- 2001-12-07 AU AU2002231697A patent/AU2002231697B2/en not_active Ceased
- 2001-12-07 CA CA2430897A patent/CA2430897C/en not_active Expired - Lifetime
- 2001-12-07 PT PT01991836T patent/PT1347743E/pt unknown
- 2001-12-07 WO PCT/EP2001/014633 patent/WO2002045688A2/en active IP Right Grant
- 2001-12-07 DK DK01991836T patent/DK1347743T3/da active
- 2001-12-07 ES ES01991836T patent/ES2260321T3/es not_active Expired - Lifetime
- 2001-12-07 EP EP01991836A patent/EP1347743B1/en not_active Expired - Lifetime
- 2001-12-07 JP JP2002547474A patent/JP4623931B2/ja not_active Expired - Fee Related
- 2001-12-07 DE DE60117858T patent/DE60117858T2/de not_active Expired - Lifetime
- 2001-12-07 AU AU3169702A patent/AU3169702A/xx active Pending
- 2001-12-07 AT AT01991836T patent/ATE319428T1/de active
-
2003
- 2003-06-05 US US10/455,257 patent/US7955618B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040037875A1 (en) | 2004-02-26 |
EP1347743B1 (en) | 2006-03-08 |
AU3169702A (en) | 2002-06-18 |
US7955618B2 (en) | 2011-06-07 |
DK1347743T3 (da) | 2006-07-03 |
DE60117858D1 (de) | 2006-05-04 |
CA2430897C (en) | 2010-11-16 |
EP1347743A2 (en) | 2003-10-01 |
WO2002045688A2 (en) | 2002-06-13 |
JP2004517835A (ja) | 2004-06-17 |
ES2260321T3 (es) | 2006-11-01 |
DE60117858T2 (de) | 2006-11-30 |
ATE319428T1 (de) | 2006-03-15 |
WO2002045688A3 (en) | 2002-11-14 |
JP4623931B2 (ja) | 2011-02-02 |
AU2002231697B2 (en) | 2006-09-07 |
CA2430897A1 (en) | 2002-06-13 |
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