PT1237856E - Novos derivados fenilicos tri-substituidos e analogos - Google Patents

Novos derivados fenilicos tri-substituidos e analogos

Info

Publication number
PT1237856E
PT1237856E PT00983619T PT00983619T PT1237856E PT 1237856 E PT1237856 E PT 1237856E PT 00983619 T PT00983619 T PT 00983619T PT 00983619 T PT00983619 T PT 00983619T PT 1237856 E PT1237856 E PT 1237856E
Authority
PT
Portugal
Prior art keywords
phenyler
analogos
substituted
new
tri
Prior art date
Application number
PT00983619T
Other languages
English (en)
Portuguese (pt)
Inventor
Maria Boije
Eva-Lotte Lindstedt Alstermark
Bengt Ohlsson
Jonas Fagerhag
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT1237856E publication Critical patent/PT1237856E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT00983619T 1999-12-03 2000-11-29 Novos derivados fenilicos tri-substituidos e analogos PT1237856E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904421A SE9904421D0 (sv) 1999-12-03 1999-12-03 New compounds

Publications (1)

Publication Number Publication Date
PT1237856E true PT1237856E (pt) 2004-08-31

Family

ID=20417986

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00983619T PT1237856E (pt) 1999-12-03 2000-11-29 Novos derivados fenilicos tri-substituidos e analogos

Country Status (23)

Country Link
US (1) US6750252B2 (enExample)
EP (1) EP1237856B1 (enExample)
JP (1) JP2003515583A (enExample)
KR (1) KR100787072B1 (enExample)
CN (1) CN1206212C (enExample)
AR (1) AR033957A1 (enExample)
AT (1) ATE266633T1 (enExample)
AU (1) AU766533B2 (enExample)
BR (1) BR0016130A (enExample)
CA (1) CA2392039A1 (enExample)
DE (1) DE60010747T2 (enExample)
DK (1) DK1237856T3 (enExample)
ES (1) ES2219425T3 (enExample)
IL (2) IL149517A0 (enExample)
MX (1) MXPA02005223A (enExample)
MY (1) MY124727A (enExample)
NO (1) NO20022590L (enExample)
PT (1) PT1237856E (enExample)
SE (1) SE9904421D0 (enExample)
TR (1) TR200401716T4 (enExample)
TW (1) TWI224590B (enExample)
WO (1) WO2001040172A1 (enExample)
ZA (1) ZA200203798B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2364304B (en) 1997-10-27 2003-04-23 Reddy Research Foundation Novel tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
HUP0101110A3 (en) 1997-10-27 2002-06-28 Reddys Lab Ltd Dr Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
EP1124807A1 (en) 1997-10-27 2001-08-22 Dr. Reddy's Research Foundation Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
BR9914438A (pt) 1998-10-29 2001-06-26 Reddy Research Foundation Processo aperfeiçoado para a preparação de novos agentes anti-diabéticos
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
US6897199B2 (en) 2001-02-05 2005-05-24 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds
SE0101386D0 (sv) 2001-04-20 2001-04-20 Astrazeneca Ab New compounds
PL369732A1 (en) * 2001-10-16 2005-05-02 Dr.Reddy's Laboratories Ltd. Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them
UA82835C2 (en) * 2001-12-03 2008-05-26 Reddys Lab Ltd Dr ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon
SE0104333D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
FR2872159B1 (fr) * 2004-06-28 2007-10-05 Merck Sante Soc Par Actions Si Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete
WO2007137260A2 (en) * 2006-05-22 2007-11-29 Elan Pharmaceuticals, Inc. Preparation of polymer conjugates of vla-4 antagonists via a mitsunobu' s reaction
KR101558005B1 (ko) 2007-03-08 2015-10-06 알비레오 에이비 2-치환-3-페닐프로피온산 유도체 및 염증성 장 질환 치료에서의 그의 용도
FR2917084B1 (fr) 2007-06-05 2009-07-17 Galderma Res & Dev Nouveaux derives d'acide 3-phenyl propanoique activateurs des recpteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques.
FR2917086B1 (fr) * 2007-06-05 2009-07-17 Galderma Res & Dev Nouveaux derives d'acide 3-phenyl acrylique activateurs des recepteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques.
DE102007038251A1 (de) * 2007-08-13 2009-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA26634A1 (fr) 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues
SE9801990D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
SE9801992D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I

Also Published As

Publication number Publication date
KR20020067537A (ko) 2002-08-22
CA2392039A1 (en) 2001-06-07
ATE266633T1 (de) 2004-05-15
NO20022590D0 (no) 2002-05-31
DE60010747T2 (de) 2005-05-19
DK1237856T3 (da) 2004-08-02
EP1237856B1 (en) 2004-05-12
US6750252B2 (en) 2004-06-15
MXPA02005223A (es) 2003-09-25
TWI224590B (en) 2004-12-01
IL149517A (en) 2007-07-04
IL149517A0 (en) 2002-11-10
CN1402703A (zh) 2003-03-12
EP1237856A1 (en) 2002-09-11
WO2001040172A1 (en) 2001-06-07
ZA200203798B (en) 2003-10-29
US20030149104A1 (en) 2003-08-07
AR033957A1 (es) 2004-01-21
AU2035101A (en) 2001-06-12
KR100787072B1 (ko) 2007-12-21
TR200401716T4 (tr) 2004-09-21
ES2219425T3 (es) 2004-12-01
SE9904421D0 (sv) 1999-12-03
JP2003515583A (ja) 2003-05-07
CN1206212C (zh) 2005-06-15
AU766533B2 (en) 2003-10-16
MY124727A (en) 2006-06-30
BR0016130A (pt) 2002-08-20
NO20022590L (no) 2002-07-29
DE60010747D1 (de) 2004-06-17

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