DE60010747D1 - Neue trisubstituierte phenyl-derivate und analoga - Google Patents

Neue trisubstituierte phenyl-derivate und analoga

Info

Publication number
DE60010747D1
DE60010747D1 DE60010747T DE60010747T DE60010747D1 DE 60010747 D1 DE60010747 D1 DE 60010747D1 DE 60010747 T DE60010747 T DE 60010747T DE 60010747 T DE60010747 T DE 60010747T DE 60010747 D1 DE60010747 D1 DE 60010747D1
Authority
DE
Germany
Prior art keywords
analog
phenyl derivatives
trisubstituted phenyl
new trisubstituted
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60010747T
Other languages
English (en)
Other versions
DE60010747T2 (de
Inventor
Maria Boije
Jonas Faegerhag
Alstermark Eva-Lotte Lindstedt
Bengt Ohlsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60010747D1 publication Critical patent/DE60010747D1/de
Publication of DE60010747T2 publication Critical patent/DE60010747T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
DE60010747T 1999-12-03 2000-11-29 Neue trisubstituierte phenyl-derivate und analoga Expired - Fee Related DE60010747T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904421 1999-12-03
SE9904421A SE9904421D0 (sv) 1999-12-03 1999-12-03 New compounds
PCT/SE2000/002385 WO2001040172A1 (en) 1999-12-03 2000-11-29 New tri-substituted phenyl derivatives and analogues

Publications (2)

Publication Number Publication Date
DE60010747D1 true DE60010747D1 (de) 2004-06-17
DE60010747T2 DE60010747T2 (de) 2005-05-19

Family

ID=20417986

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010747T Expired - Fee Related DE60010747T2 (de) 1999-12-03 2000-11-29 Neue trisubstituierte phenyl-derivate und analoga

Country Status (23)

Country Link
US (1) US6750252B2 (de)
EP (1) EP1237856B1 (de)
JP (1) JP2003515583A (de)
KR (1) KR100787072B1 (de)
CN (1) CN1206212C (de)
AR (1) AR033957A1 (de)
AT (1) ATE266633T1 (de)
AU (1) AU766533B2 (de)
BR (1) BR0016130A (de)
CA (1) CA2392039A1 (de)
DE (1) DE60010747T2 (de)
DK (1) DK1237856T3 (de)
ES (1) ES2219425T3 (de)
IL (2) IL149517A0 (de)
MX (1) MXPA02005223A (de)
MY (1) MY124727A (de)
NO (1) NO20022590L (de)
PT (1) PT1237856E (de)
SE (1) SE9904421D0 (de)
TR (1) TR200401716T4 (de)
TW (1) TWI224590B (de)
WO (1) WO2001040172A1 (de)
ZA (1) ZA200203798B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100376560C (zh) 1997-10-27 2008-03-26 雷迪实验室有限公司 新型三环化合物和其作为药物的用途;其制备方法和包含该化合物的药物组合物
AU752059B2 (en) 1997-10-27 2002-09-05 Dr. Reddy's Laboratories Limited Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
AU1198699A (en) 1997-10-27 1999-04-23 Dr. Reddy's Research Foundation Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
CN1323300A (zh) 1998-10-29 2001-11-21 雷迪研究基金会 制备新的抗糖尿病剂的改进方法
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
US6897199B2 (en) 2001-02-05 2005-05-24 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds
SE0101386D0 (sv) 2001-04-20 2001-04-20 Astrazeneca Ab New compounds
PL369732A1 (en) * 2001-10-16 2005-05-02 Dr.Reddy's Laboratories Ltd. Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them
UA82835C2 (en) 2001-12-03 2008-05-26 Reddys Lab Ltd Dr ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon
SE0104333D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
FR2872159B1 (fr) * 2004-06-28 2007-10-05 Merck Sante Soc Par Actions Si Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete
JP2009538338A (ja) * 2006-05-22 2009-11-05 イーラン ファーマスーティカルズ、インコーポレイテッド 治療用、農業用及び食品添加用化合物のポリマー複合体の調製
ES2445049T3 (es) 2007-03-08 2014-02-27 Albireo Ab Derivados del ácido 3-fenilpropiónico y su uso en el tratamiento de la enfermedad inflamatoria intestinal
FR2917084B1 (fr) * 2007-06-05 2009-07-17 Galderma Res & Dev Nouveaux derives d'acide 3-phenyl propanoique activateurs des recpteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques.
FR2917086B1 (fr) * 2007-06-05 2009-07-17 Galderma Res & Dev Nouveaux derives d'acide 3-phenyl acrylique activateurs des recepteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques.
DE102007038251A1 (de) * 2007-08-13 2009-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
SE9801992D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (fr) 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues

Also Published As

Publication number Publication date
NO20022590L (no) 2002-07-29
NO20022590D0 (no) 2002-05-31
ATE266633T1 (de) 2004-05-15
EP1237856A1 (de) 2002-09-11
AR033957A1 (es) 2004-01-21
CA2392039A1 (en) 2001-06-07
TR200401716T4 (tr) 2004-09-21
ES2219425T3 (es) 2004-12-01
US6750252B2 (en) 2004-06-15
WO2001040172A1 (en) 2001-06-07
US20030149104A1 (en) 2003-08-07
AU2035101A (en) 2001-06-12
CN1402703A (zh) 2003-03-12
KR20020067537A (ko) 2002-08-22
KR100787072B1 (ko) 2007-12-21
IL149517A (en) 2007-07-04
MY124727A (en) 2006-06-30
AU766533B2 (en) 2003-10-16
PT1237856E (pt) 2004-08-31
IL149517A0 (en) 2002-11-10
DK1237856T3 (da) 2004-08-02
CN1206212C (zh) 2005-06-15
TWI224590B (en) 2004-12-01
MXPA02005223A (es) 2003-09-25
ZA200203798B (en) 2003-10-29
SE9904421D0 (sv) 1999-12-03
JP2003515583A (ja) 2003-05-07
BR0016130A (pt) 2002-08-20
DE60010747T2 (de) 2005-05-19
EP1237856B1 (de) 2004-05-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee