PT1202727E - Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina - Google Patents
Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotinaInfo
- Publication number
- PT1202727E PT1202727E PT00947901T PT00947901T PT1202727E PT 1202727 E PT1202727 E PT 1202727E PT 00947901 T PT00947901 T PT 00947901T PT 00947901 T PT00947901 T PT 00947901T PT 1202727 E PT1202727 E PT 1202727E
- Authority
- PT
- Portugal
- Prior art keywords
- nicotine
- therapy
- utilization
- receptor agonists
- abstinence
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 3
- 229960002715 nicotine Drugs 0.000 title abstract 3
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 3
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 title 1
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 239000000556 agonist Substances 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI001715A IT1313585B1 (it) | 1999-07-30 | 1999-07-30 | Uso di agonisti dei recettori gabab per la terapia di mantenimentodell'astinenza da nicotina in soggetti nicotino-dipendenti. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1202727E true PT1202727E (pt) | 2005-05-31 |
Family
ID=11383467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00947901T PT1202727E (pt) | 1999-07-30 | 2000-06-30 | Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1202727B1 (enExample) |
| CN (1) | CN1176650C (enExample) |
| AT (1) | ATE285763T1 (enExample) |
| AU (1) | AU6153400A (enExample) |
| CA (1) | CA2379752C (enExample) |
| DE (1) | DE60017147T2 (enExample) |
| DK (1) | DK1202727T3 (enExample) |
| ES (1) | ES2235913T3 (enExample) |
| HK (1) | HK1046849B (enExample) |
| IL (2) | IL147876A0 (enExample) |
| IT (1) | IT1313585B1 (enExample) |
| PL (1) | PL196334B1 (enExample) |
| PT (1) | PT1202727E (enExample) |
| RU (1) | RU2262352C2 (enExample) |
| SI (1) | SI1202727T1 (enExample) |
| WO (1) | WO2001008675A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005019163A2 (en) * | 2003-08-20 | 2005-03-03 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
| EP2354120A1 (en) | 2003-08-20 | 2011-08-10 | XenoPort, Inc. | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof |
| WO2006050471A2 (en) | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
| WO2006050472A2 (en) | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids |
| US7585996B2 (en) | 2006-09-15 | 2009-09-08 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
| JP4498407B2 (ja) | 2006-12-22 | 2010-07-07 | キヤノン株式会社 | プロセスカートリッジ、電子写真画像形成装置、及び、電子写真感光体ドラムユニット |
| JP5291123B2 (ja) | 2008-01-25 | 2013-09-18 | ゼノポート，インコーポレイティド | （３ｓ）−アミノメチル−５−ヘキサン酸プロドラッグの結晶形態及びその使用 |
| WO2009094577A2 (en) | 2008-01-25 | 2009-07-30 | Xenoport, Inc. | Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use |
| EP2250148B1 (en) | 2008-01-25 | 2016-08-17 | XenoPort, Inc. | Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use |
| US7989641B2 (en) | 2008-08-07 | 2011-08-02 | Xenoport, Inc. | Methods of synthesizing N-hydroxysuccinimidyl carbonates |
| WO2010017504A1 (en) | 2008-08-07 | 2010-02-11 | Xenoport, Inc. | Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs |
| JP2012519212A (ja) | 2009-03-03 | 2012-08-23 | ゼノポート，インコーポレイティド | Ｒ−バクロフェンプロドラッグの持効性放出経口投与形 |
| US8344028B2 (en) | 2009-04-17 | 2013-01-01 | Xenoport, Inc. | Gamma-amino-butyric acid derivatives as GABAB receptor ligands |
| WO2011081558A1 (ru) * | 2009-08-21 | 2011-07-07 | Komissarov Jury Vladimirovich | Курительное устройство для отказа от табачного курения |
| US8580850B2 (en) | 2011-08-11 | 2013-11-12 | Xenoport, Inc. | Anhydrous and hemihydrate crystalline forms of an (R)-baclofen prodrug, methods of synthesis and methods of use |
| WO2019195813A1 (en) * | 2018-04-06 | 2019-10-10 | Ovid Therapeutics Inc. | Use of gaboxadol in the treatment of substance use disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4126684A (en) * | 1976-02-11 | 1978-11-21 | Ciba-Geigy Corporation | 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse |
| US5073539A (en) * | 1990-01-22 | 1991-12-17 | Ciba-Geigy Corporation | Transdermal administration of zwitterionic drugs |
| US5760049A (en) * | 1997-02-21 | 1998-06-02 | Synapse Pharmaceuticals International, Inc. | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use |
| US6541520B1 (en) * | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
| RU2132203C1 (ru) * | 1998-09-03 | 1999-06-27 | Шакирзянов Галимзян Закирович | Способ лечения табачной зависимости и антитабачный комбинированный препарат |
-
1999
- 1999-07-30 IT IT1999MI001715A patent/IT1313585B1/it active
-
2000
- 2000-06-30 WO PCT/EP2000/006120 patent/WO2001008675A1/en not_active Ceased
- 2000-06-30 CN CNB00811031XA patent/CN1176650C/zh not_active Expired - Lifetime
- 2000-06-30 CA CA002379752A patent/CA2379752C/en not_active Expired - Fee Related
- 2000-06-30 PL PL353373A patent/PL196334B1/pl unknown
- 2000-06-30 DK DK00947901T patent/DK1202727T3/da active
- 2000-06-30 EP EP00947901A patent/EP1202727B1/en not_active Expired - Lifetime
- 2000-06-30 AT AT00947901T patent/ATE285763T1/de active
- 2000-06-30 IL IL14787600A patent/IL147876A0/xx active IP Right Grant
- 2000-06-30 ES ES00947901T patent/ES2235913T3/es not_active Expired - Lifetime
- 2000-06-30 PT PT00947901T patent/PT1202727E/pt unknown
- 2000-06-30 RU RU2002105375/15A patent/RU2262352C2/ru active
- 2000-06-30 SI SI200030632T patent/SI1202727T1/xx unknown
- 2000-06-30 HK HK02107911.9A patent/HK1046849B/en not_active IP Right Cessation
- 2000-06-30 DE DE60017147T patent/DE60017147T2/de not_active Expired - Lifetime
- 2000-06-30 AU AU61534/00A patent/AU6153400A/en not_active Abandoned
-
2002
- 2002-01-28 IL IL147876A patent/IL147876A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1202727T1 (enExample) | 2005-08-31 |
| CA2379752C (en) | 2008-05-27 |
| DE60017147T2 (de) | 2006-01-12 |
| CN1377265A (zh) | 2002-10-30 |
| DK1202727T3 (da) | 2005-05-09 |
| EP1202727A1 (en) | 2002-05-08 |
| ATE285763T1 (de) | 2005-01-15 |
| ITMI991715A0 (it) | 1999-07-30 |
| HK1046849B (en) | 2005-07-15 |
| IL147876A0 (en) | 2002-08-14 |
| RU2262352C2 (ru) | 2005-10-20 |
| DE60017147D1 (de) | 2005-02-03 |
| CN1176650C (zh) | 2004-11-24 |
| HK1046849A1 (en) | 2003-01-30 |
| IT1313585B1 (it) | 2002-09-09 |
| EP1202727B1 (en) | 2004-12-29 |
| ITMI991715A1 (it) | 2001-01-30 |
| PL353373A1 (en) | 2003-11-17 |
| AU6153400A (en) | 2001-02-19 |
| WO2001008675A1 (en) | 2001-02-08 |
| CA2379752A1 (en) | 2001-02-08 |
| IL147876A (en) | 2007-06-17 |
| PL196334B1 (pl) | 2007-12-31 |
| ES2235913T3 (es) | 2005-07-16 |
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