HUP9700806A2 - Tianeptin-nátriumsó nyújtott felszabadulását biztosító, szájon át beadható mátrix tabletta és eljárás előállítására - Google Patents
Tianeptin-nátriumsó nyújtott felszabadulását biztosító, szájon át beadható mátrix tabletta és eljárás előállításáraInfo
- Publication number
- HUP9700806A2 HUP9700806A2 HU9700806A HUP9700806A HUP9700806A2 HU P9700806 A2 HUP9700806 A2 HU P9700806A2 HU 9700806 A HU9700806 A HU 9700806A HU P9700806 A HUP9700806 A HU P9700806A HU P9700806 A2 HUP9700806 A2 HU P9700806A2
- Authority
- HU
- Hungary
- Prior art keywords
- matrix tablet
- sodium salt
- tianeptine
- preparation
- prolonged release
- Prior art date
Links
- 239000013563 matrix tablet Substances 0.000 title abstract 3
- JICJBGPOMZQUBB-UHFFFAOYSA-N 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid Chemical compound O=S1(=O)N(C)C2=CC=CC=C2C(NCCCCCCC(O)=O)C2=CC=C(Cl)C=C21 JICJBGPOMZQUBB-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title 1
- 159000000000 sodium salts Chemical class 0.000 title 1
- 229960005138 tianeptine Drugs 0.000 title 1
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
- 208000024963 hair loss Diseases 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 239000004575 stone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
A találmány tárgya tianeptin-nátriűmsó nyújtőtt felszabadűlásátbiztősító mátrixtabletta, mely galenikűs főrmában őrális útőn adhatóbe, és felszívódás űtán a vérben állandó és egyenletes kőncentrációtbiztősít. A találmány tárgya tővábbá eljárás a mátrixtabletta előállítására. Atianeptin elsősőrban szőrőngás és depresszió kezelésére alkalmas. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9605174A FR2747921B1 (fr) | 1996-04-24 | 1996-04-24 | Comprime matriciel permettant la liberation prolongee du sel de sodium de tianeptine apres administration par voie orale |
Publications (4)
Publication Number | Publication Date |
---|---|
HU9700806D0 HU9700806D0 (en) | 1997-06-30 |
HUP9700806A2 true HUP9700806A2 (hu) | 1998-10-28 |
HUP9700806A3 HUP9700806A3 (en) | 2000-01-28 |
HU224192B1 HU224192B1 (hu) | 2005-06-28 |
Family
ID=9491549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9700806A HU224192B1 (hu) | 1996-04-24 | 1997-04-24 | Tianeptin-nátriumsó nyújtott felszabadulását biztosító, szájon át beadható mátrix tabletta és eljárás előállítására |
Country Status (18)
Country | Link |
---|---|
US (1) | US5888542A (hu) |
EP (1) | EP0803253B1 (hu) |
JP (1) | JPH1036268A (hu) |
CN (1) | CN1116029C (hu) |
AT (1) | ATE205715T1 (hu) |
AU (1) | AU719822B2 (hu) |
CA (1) | CA2203310C (hu) |
DE (1) | DE69706748T2 (hu) |
DK (1) | DK0803253T3 (hu) |
ES (1) | ES2164310T3 (hu) |
FR (1) | FR2747921B1 (hu) |
GR (1) | GR3037043T3 (hu) |
HU (1) | HU224192B1 (hu) |
NO (1) | NO315407B1 (hu) |
NZ (1) | NZ314662A (hu) |
PL (1) | PL188135B1 (hu) |
PT (1) | PT803253E (hu) |
ZA (1) | ZA973495B (hu) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2791891A1 (fr) * | 1999-04-07 | 2000-10-13 | Adir | Utilisation de la tianeptine pour l'obtention de medicaments destines au traitement des pathologies de la neurodegenerescence |
US6683072B1 (en) | 2003-02-04 | 2004-01-27 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia |
AP1899A (en) * | 2003-08-08 | 2008-10-10 | Biovail Lab Int Srl | Modified-release tablet of bupropion hydrochloride |
US20050227961A1 (en) * | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
US9314469B2 (en) | 2008-05-05 | 2016-04-19 | Tonix Pharma Holdings Limited | Method for treating neurocognitive dysfunction |
US8198268B2 (en) | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
US20110237537A1 (en) * | 2009-05-29 | 2011-09-29 | Lombard Jay L | Methods for assessment and treatment of mood disorders via single nucleotide polymorphisms analysis |
WO2010138796A2 (en) * | 2009-05-29 | 2010-12-02 | Genomind, Llc | Methods for assessment and treatment of depression via utilization of single nucleotide polymorphisms analysis |
US8355927B2 (en) | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
KR20120092993A (ko) * | 2011-02-14 | 2012-08-22 | 지엘팜텍 주식회사 | 티아넵틴 또는 이의 약제학적으로 허용되는 염을 포함하는 경구투여용 서방성 정제 |
PL2561864T3 (pl) * | 2011-08-25 | 2015-05-29 | Zakl Farmaceutyczne Polpharma Sa | Tabletka powlekana zawierająca tianeptynę i sposób jej otrzymywania |
KR101136976B1 (ko) * | 2011-09-06 | 2012-05-30 | 건일제약 주식회사 | 티아넵틴 또는 그의 염을 포함하는 탈모증의 예방 또는 치료용 약학 조성물 |
GB201208315D0 (en) | 2012-05-11 | 2012-06-27 | Numedicus Ltd | Pharmaceutical methods and compositions |
CN104031005B (zh) * | 2014-05-30 | 2016-04-27 | 济南诚汇双达化工有限公司 | 一种噻萘普汀钠中间体的制备方法 |
KR20180101307A (ko) | 2018-09-04 | 2018-09-12 | 지엘팜텍주식회사 | 티아넵틴 또는 이의 약제학적으로 허용되는 염을 포함하는 경구투여용 서방성 정제 |
KR20200104265A (ko) | 2020-08-21 | 2020-09-03 | 지엘팜텍주식회사 | 티아넵틴 또는 이의 약제학적으로 허용되는 염을 포함하는 경구투여용 서방성 정제 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
FR2635461B1 (fr) * | 1988-08-18 | 1992-01-17 | Adir | Utilisation de derives tricycliques pour l'obtention de medicaments destines au traitement du stress |
FR2716623B1 (fr) * | 1994-02-25 | 1996-08-23 | Adir | Utilisation d'un dérivé tricyclique pour l'obtention de médicaments destinés au traitement des troubles mnémo-cognitifs. |
-
1996
- 1996-04-24 FR FR9605174A patent/FR2747921B1/fr not_active Expired - Fee Related
-
1997
- 1997-04-14 JP JP9095589A patent/JPH1036268A/ja active Pending
- 1997-04-22 CA CA002203310A patent/CA2203310C/fr not_active Expired - Fee Related
- 1997-04-22 AU AU19041/97A patent/AU719822B2/en not_active Ceased
- 1997-04-23 PT PT97400911T patent/PT803253E/pt unknown
- 1997-04-23 NO NO19971860A patent/NO315407B1/no not_active IP Right Cessation
- 1997-04-23 EP EP97400911A patent/EP0803253B1/fr not_active Expired - Lifetime
- 1997-04-23 DK DK97400911T patent/DK0803253T3/da active
- 1997-04-23 DE DE69706748T patent/DE69706748T2/de not_active Expired - Lifetime
- 1997-04-23 AT AT97400911T patent/ATE205715T1/de active
- 1997-04-23 CN CN97110799A patent/CN1116029C/zh not_active Expired - Lifetime
- 1997-04-23 US US08/844,942 patent/US5888542A/en not_active Expired - Lifetime
- 1997-04-23 ZA ZA9703495A patent/ZA973495B/xx unknown
- 1997-04-23 ES ES97400911T patent/ES2164310T3/es not_active Expired - Lifetime
- 1997-04-23 PL PL97319627A patent/PL188135B1/pl not_active IP Right Cessation
- 1997-04-23 NZ NZ314662A patent/NZ314662A/xx not_active IP Right Cessation
- 1997-04-24 HU HU9700806A patent/HU224192B1/hu not_active IP Right Cessation
-
2001
- 2001-10-30 GR GR20010401915T patent/GR3037043T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0803253A1 (fr) | 1997-10-29 |
FR2747921B1 (fr) | 1998-10-30 |
PL319627A1 (en) | 1997-10-27 |
CN1116029C (zh) | 2003-07-30 |
HUP9700806A3 (en) | 2000-01-28 |
DE69706748D1 (de) | 2001-10-25 |
FR2747921A1 (fr) | 1997-10-31 |
NZ314662A (en) | 1998-12-23 |
CA2203310C (fr) | 2001-10-23 |
JPH1036268A (ja) | 1998-02-10 |
ES2164310T3 (es) | 2002-02-16 |
PT803253E (pt) | 2001-12-28 |
EP0803253B1 (fr) | 2001-09-19 |
ATE205715T1 (de) | 2001-10-15 |
ZA973495B (en) | 1997-11-18 |
NO315407B1 (no) | 2003-09-01 |
GR3037043T3 (en) | 2002-01-31 |
CA2203310A1 (fr) | 1997-10-24 |
HU224192B1 (hu) | 2005-06-28 |
CN1168792A (zh) | 1997-12-31 |
AU1904197A (en) | 1997-10-30 |
AU719822B2 (en) | 2000-05-18 |
NO971860D0 (no) | 1997-04-23 |
DE69706748T2 (de) | 2002-07-04 |
NO971860L (no) | 1997-10-27 |
DK0803253T3 (da) | 2001-11-19 |
US5888542A (en) | 1999-03-30 |
HU9700806D0 (en) | 1997-06-30 |
PL188135B1 (pl) | 2004-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20050420 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |