PT1202727E - Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina - Google Patents

Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina

Info

Publication number
PT1202727E
PT1202727E PT00947901T PT00947901T PT1202727E PT 1202727 E PT1202727 E PT 1202727E PT 00947901 T PT00947901 T PT 00947901T PT 00947901 T PT00947901 T PT 00947901T PT 1202727 E PT1202727 E PT 1202727E
Authority
PT
Portugal
Prior art keywords
nicotine
therapy
utilization
receptor agonists
abstinence
Prior art date
Application number
PT00947901T
Other languages
English (en)
Inventor
Gessa Gian Luigi
Colombo Giancarlo
Pani Luca
Fratta Walter
Original Assignee
Molteni & C
O S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molteni & C, O S P A filed Critical Molteni & C
Publication of PT1202727E publication Critical patent/PT1202727E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT00947901T 1999-07-30 2000-06-30 Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina PT1202727E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001715A IT1313585B1 (it) 1999-07-30 1999-07-30 Uso di agonisti dei recettori gabab per la terapia di mantenimentodell'astinenza da nicotina in soggetti nicotino-dipendenti.

Publications (1)

Publication Number Publication Date
PT1202727E true PT1202727E (pt) 2005-05-31

Family

ID=11383467

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00947901T PT1202727E (pt) 1999-07-30 2000-06-30 Utilizacao de agonistas de receptores gabab e seus derivados farmaceuticamente aceitaveis, na terapia para manter a abstinencia de nicotina em pacientes dependentes de nicotina

Country Status (16)

Country Link
EP (1) EP1202727B1 (pt)
CN (1) CN1176650C (pt)
AT (1) ATE285763T1 (pt)
AU (1) AU6153400A (pt)
CA (1) CA2379752C (pt)
DE (1) DE60017147T2 (pt)
DK (1) DK1202727T3 (pt)
ES (1) ES2235913T3 (pt)
HK (1) HK1046849B (pt)
IL (2) IL147876A0 (pt)
IT (1) IT1313585B1 (pt)
PL (1) PL196334B1 (pt)
PT (1) PT1202727E (pt)
RU (1) RU2262352C2 (pt)
SI (1) SI1202727T1 (pt)
WO (1) WO2001008675A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1660440E (pt) 2003-08-20 2012-05-15 Xenoport Inc Pró-fármacos de aciloxialquilcarbamato, métodos de síntese e utilização
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US7494985B2 (en) 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2006050471A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7585996B2 (en) 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
JP4498407B2 (ja) 2006-12-22 2010-07-07 キヤノン株式会社 プロセスカートリッジ、電子写真画像形成装置、及び、電子写真感光体ドラムユニット
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
TWI369202B (en) 2008-01-25 2012-08-01 Xenoport Inc Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
EP2250148B1 (en) 2008-01-25 2016-08-17 XenoPort, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
US7989641B2 (en) 2008-08-07 2011-08-02 Xenoport, Inc. Methods of synthesizing N-hydroxysuccinimidyl carbonates
US8299291B2 (en) 2008-08-07 2012-10-30 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
NZ594648A (en) 2009-03-03 2013-12-20 Xenoport Inc Sustained release oral dosage forms of an r-baclofen prodrug
CA2758245A1 (en) 2009-04-17 2010-10-21 Xenoport, Inc. Gamma-amino-butyric acid derivatives as gabab receptor ligands
WO2011081558A1 (ru) * 2009-08-21 2011-07-07 Komissarov Jury Vladimirovich Курительное устройство для отказа от табачного курения
WO2013023155A1 (en) 2011-08-11 2013-02-14 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use
AU2019249277A1 (en) * 2018-04-06 2020-10-22 Ovid Therapeutics Inc. Use of gaboxadol in the treatment of substance use disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126684A (en) * 1976-02-11 1978-11-21 Ciba-Geigy Corporation 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
US5073539A (en) * 1990-01-22 1991-12-17 Ciba-Geigy Corporation Transdermal administration of zwitterionic drugs
US5760049A (en) * 1997-02-21 1998-06-02 Synapse Pharmaceuticals International, Inc. Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
US6541520B1 (en) * 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior

Also Published As

Publication number Publication date
SI1202727T1 (pt) 2005-08-31
WO2001008675A1 (en) 2001-02-08
ITMI991715A0 (it) 1999-07-30
ITMI991715A1 (it) 2001-01-30
CN1377265A (zh) 2002-10-30
DK1202727T3 (da) 2005-05-09
EP1202727B1 (en) 2004-12-29
PL196334B1 (pl) 2007-12-31
RU2262352C2 (ru) 2005-10-20
DE60017147D1 (de) 2005-02-03
ES2235913T3 (es) 2005-07-16
CA2379752C (en) 2008-05-27
HK1046849A1 (en) 2003-01-30
IT1313585B1 (it) 2002-09-09
ATE285763T1 (de) 2005-01-15
PL353373A1 (en) 2003-11-17
CA2379752A1 (en) 2001-02-08
IL147876A (en) 2007-06-17
AU6153400A (en) 2001-02-19
EP1202727A1 (en) 2002-05-08
IL147876A0 (en) 2002-08-14
HK1046849B (zh) 2005-07-15
CN1176650C (zh) 2004-11-24
DE60017147T2 (de) 2006-01-12

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